Adenovirus belongs to the family Adenoviridae This is a double stranded DNA virus Does not possess an envelope Adenovirus is icosahedral in shape Thus not easily destroyed It’s name is given as this virus is first isolated from the add noise But this virus can affect several systems and cause several illnesses Adenovirus affects respiratory system, gastrointestinal system, genitourinary system and the eye So this virus has many serotypes

1. Adenovirus

2. Adenovirus
• Family - Adenoviridae
• ds DNA
• Non enveloped
• Icosahedral
• Not easily destroyed
• Many serotypes
• Affects respiratory, gastrointestinal and genitourinary systems and
the eye

3. ln details
• Adenovirus belongs to the family Adenoviridae
• This is a double stranded DNA virus
• Does not possess an envelope
• Adenovirus is icosahedral in shape
• Thus not easily destroyed
• It’s name is given as this virus is first isolated from the add noise
• But this virus can affect several systems and cause several illnesses
• Adenovirus affects respiratory system, gastrointestinal system,
genitourinary system and the eye
• So this virus has many serotypes

4. Commonest
cause of
pharyngitis

5. Transmission
• Close personal contact, such as touching or shaking hands
• The air by coughing and sneezing
• Touching an object or surface with adenoviruses on it, then touching
your mouth, nose, or eyes before washing your hands
• Ingestion

7. Respiratory diseases
• Pharyngitis
• Serotypes 1,2,3,5,7
• Acute respiratory disease
• Serotypes 4,7,14,21
• Pharyngoconjuctival fever
• Serotypes 3,7
• Pneumonia
• Stereotypes 1,2,3,7

8. GIT infections
• Acute gastroenteritis
• Stereotypes 40, 41

9. GU infections
• Acute haemorrhagic cystitis
• Stereotypes 11, 21

10. Eye infections
• Acute follicular conjunctivitis
• Epidemic keratoconjunctivitis

11. Acute follicular conjunctivitis
• Cause by serotypes 3, 4, 11

12. Epidemic keratoconjunctivitis
• Aggressive conjunctivitis and keratitis
• Pain
• Photophobia
• Highly contagious
• Caused by serotypes 8, 9, 37

13. Acute gastroenteritis
• Year round prevalence
• Outbreaks reported in crowded places like hospitals, orphanages
• Age less than 4 years, more affected
• Caused by enteric adenoviruses, serotypes 40 & 41

14. Pharyngo-conjunctival fever
• Conjunctivitis
• In 1/3 to ½ cases
• Commonly unilateral, but bilateral in ¼ cases
• Fever
• Pharyngitis
• Pharyngeal erythema & educate may mimic Streptococcal pharyngitis
• Adenoid enlargement
• This is a swimming pool associated illness due to inadequate
chlorination of water
• Caused by serotypes 3 & 7

15. Samples collected
• Eye swabs
• Nasopharyngeal aspirate
• Throat swabs

16. Laboratory diagnosis
• Virus isolation
• Antigen detection by immunofluorescence
• PCR

17. Management
• No antiviral treatment
• Supportive care

18. No
vaccination
for
adenovirus

19. Infection control measures
• Wash your hands often with soap and water
• Avoid touching your eyes, nose, and mouth with unwashed hands
• Avoid close contact with people who are sick
• Stay home when you are sick
• Cover your mouth and nose when coughing or sneezing
• Adequate chlorination of water

20. Thank
You!