One of the most common illnesses to man Leading cause of doctor visits and lost hours both at school and the workplace Over 200 different viruses found to cause symptoms of the common cold

1. RHINOVIRUS
DR FARIA ASHRAF

2. aka common cold virus
• One of the most common illnesses to man
• Leading cause of doctor visits and lost hours
both at school and the workplace
• Over 200 different viruses found to cause
symptoms of the common cold
• 35 to 50% of the total number of common
colds
• Hand to hand contact transmission

3. MORPHOLOGY
• Each facet is divided into 60 triangles ►Each
contains one of the following: VP1, VP2, VP3
(VP4 is found on the inside) -VP1 proteins
form a protrusion at the 5 fold axis -around
this protrusion is a depression known as the
‘canyon’ -the canyon is where cell receptors
bond to the virus

5. • Picornaviridae family
• Incubation period of 1 to 3 days
• Optimum growth occurs between 33 and 34
deg Celsius (93 deg F)
• Not stable below the pH of 5-6

6. MODE OF TRANSMISSION
• There are two modes of transmission: via
aerosols of respiratory droplets and from
contaminated surfaces, including direct
person-to-person contact(hand to hand).

7. PATHOGENESIS
• Entry through Respiratory tract.
• Nasal Mucosa, can infect Lower Respiratory
tract.
• Chilling, wearing wet cloths do not produce
infection (But common cold starts with chills).
• Local inflammation and cytokines may be
responsible for the symptoms of common
cold.

8. C/F
• Incubation period is 2-4 days
• Last for 7 days.
• Sneezing, nasal obstruction, sore throat
• May lead to secondary infections with
bacteria.

9. L.D.
• Isolation of virus may be obtained from nasal
or throat swabs collected early in infection.

10. TREATMENT AND PREVENTION
• Treatment is mainly supportive
• No specific treatment because treatments are still experimental .
• Vaccines are unsuccessful.
• Intranasal spray of Gamma Interferon for 5 Days
• DRACO, a broad-spectrum antiretroviral therapy being developed at
the Massachusetts Institute of Technology, has shown preliminary
effectiveness in treating rhinovirus, as well as a number of other
infectious viruses
• PREVENTION • There is no vaccine to protect you against the
common cold. However, you may be able to reduce your risk of
getting a cold by • WASHING YOUR HANDS REGULARLY WITH SOAP
• USE FACIAL TISSUE TO SNEEZE • COVER NOSE WHEN U SNEEZE •
COVER MOUTH WHEN U COUGH • AVOID SICK PEOPLE • AVOID
NOSE AND MOUTH TOUCHING WITH DIRTY HANDS

11. Thank you!!