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VIROSES
DE INTERESSE
EM ODONTOLOGIA
1. INTRODUÇÃO
 DERMATRÓPICOS
→ CICLO EVOLUTIVO
- MÁCULA
- PÁPULA
- VESÍCULA
- PÚSTULA
- ÁREA DE NECROSE
- CROSTA
- ÁREA INTACTA
→ DIVISÃO
- MÁCULO – PAPULARES
DEFINIÇÃO
EXANTEMA
ENANTEMA
Ex: SARAMPO, RUBÉOLA
- VESÍCULO – PUSTULARES
DEFINIÇÃO
Ex: HERPES SIMPLES, VARÍOLA, CATAPORA
→ TROPISMO E OUTROS ÓRGÃOS
→ OUTROS VÍRUS DE INTERESSE: HEPATITE, AIDS, RESPIRATÓRIOS
2. SARAMPO
 AGENTE CAUSAL
- FAMÍLIA: Paramyxoviridae
- GÊNERO: Morbilivirus
 TRANSMISSÃO
- PESSOA – A – PESSOA; AR
- 8 A 12 DIAS (CRIANÇAS); 21 DIAS (ADULTOS)
Obs.: SECREÇÕES DE NASOFARINGE, OLHOS, URINA
 DISSEMINAÇÃO
- TRATO RESPIRATÓRIO → SRE → MUCOSA BUCAL (MANCHAS
DE KOPLIK) → MÁCULAS e ENANTEMAS
 COMPLICAÇÕES
- INFECÇÕES BACTERIANAS SECUNDÁRIAS
- PANENCEFALITE ESCLEROSANTE SUBAGUDA
3. RUBÉOLA
 AGENTE CAUSAL
- FAMÍLIA Togaviridae
- GÊNERO Rubivirus
 TRANSMISSÃO
- PESSOA – A – PESSOA; AR
- 12 a 36 DIAS
 DISSEMINAÇÃO
- TRATO RESPIRATÓRIO → SANGUE → LESÕES CUTÂNEAS (4 a
7 DIAS)
Obs.: RUBÉOLA CONGÊNITA
- ABORTO
- CATARATA, MICROCEFALIA, DEFEITOS ÓSSEOS,
RETARDO MENTAL, DEFEITOS CARDÍACOS
- HIPOPLASIA DE ESMALTE, PALATO FENDIDO, IRRUPÇÃO
DENTAL RETARDADA
4. HERPESVÍRUS
 AGENTE CAUSAL
- SUBFAMÍLIA Alphaherperviridae
- SUBFAMÍLIA Beta e Gamaherpesviridae
 TIPOS DE INFECÇÃO
- CICLO LÍTICO
- CICLO LISOGÊNICO
LATENTE
ONCOGÊNICA
4.1 HERPES SIMPLES
 TRANSMISSÃO
- PELE e MUCOSAS
- HSV-1: 6 MESES a 3 ANOS
- HSV- 2: ADOLESCÊNCIA
 DISSEMINAÇÃO
- CÉLUAS EPITELIAIS → SANGUE → ÓRGÃOS ALVO → ESTÁGIOS
DAS LESÕES
- Obs.: MIGRAÇÃO GANGLIONAR E LATÊNCIA
 MANIFESTAÇÕES CLÍNICAS
→ HSV-1: GENGIVOESTOMATITE HERPÉTICA
- ERUPÇÃO VARICELIFORME DE KAPOSI
- CERATOCONJUNTIVITE
→ HSV-2: VULVOVAGINITE HERPÉTICA; MENINGOENCEFALITE
Obs.: SARCOMA DE KAPOSI (HSV-8)
PERIODONTITE E HERPESVÍRUS
- HSV-1, CMV, EBV
- QUEDA NA RESISTÊNCIA
4.2 CITOMEGALIA
 AGENTE CAUSAL
- CITOMEGALOVÍRUS (HHV-5; Betaherpesviridae)
 MANIFESTAÇÕES CLÍNICAS
→ INFECÇÕES PRIMÁRIAS: PROGNÓSTICO FAVORÁVEL
- MANIFESTAÇÕES BUCAIS
GENGIVITE
ULCERAÇÕES ERITEMATOSAS NAS MUCOSAS
XEROSTOMIA
→ INFECÇÕES CONGÊNITAS
- NEUROLÓGICAS
4.3 MONONUCLEOSE INFECCIOSA
 AGENTE CAUSAL
→ VÍRUS EPSTEIN-BARR (HHV-4; Betaherpesviridae)
 DISSEMINAÇÃO
→ SALIVA (DOENÇA DO BEIJO)
→ LINFÓCITOS B e T
 SINTOMATOLOGIA
- MAL-ESTAR, DOR DE CABEÇA, FEBRE, DOR DE GARGANTA
LINFADENOPATIA
Obs.: LEUCOPLASIA PILOSA (AIDS)
5. CAXUMBA
 AGENTE CAUSAL
- FAMÍLIA Paramyxoviridae
 TRANSMISSÃO
- GOTÍCULAS DE SALIVA; FÔMITES
- 12 a 36 DIAS
 SINTOMATOLOGIA
- FEBRE, OTALGIA, CEFALÉIA
- INTUMESCIMENTO DAS PARÓTIDAS
- VIREMIAS: OOFORITE, ORQUITE, HEPATITE, PANCREATITE
SNS, TIREÓIDE

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10536089(1).ppt

  • 2. 1. INTRODUÇÃO  DERMATRÓPICOS → CICLO EVOLUTIVO - MÁCULA - PÁPULA - VESÍCULA - PÚSTULA - ÁREA DE NECROSE - CROSTA - ÁREA INTACTA
  • 3. → DIVISÃO - MÁCULO – PAPULARES DEFINIÇÃO EXANTEMA ENANTEMA Ex: SARAMPO, RUBÉOLA - VESÍCULO – PUSTULARES DEFINIÇÃO Ex: HERPES SIMPLES, VARÍOLA, CATAPORA → TROPISMO E OUTROS ÓRGÃOS → OUTROS VÍRUS DE INTERESSE: HEPATITE, AIDS, RESPIRATÓRIOS
  • 4. 2. SARAMPO  AGENTE CAUSAL - FAMÍLIA: Paramyxoviridae - GÊNERO: Morbilivirus  TRANSMISSÃO - PESSOA – A – PESSOA; AR - 8 A 12 DIAS (CRIANÇAS); 21 DIAS (ADULTOS) Obs.: SECREÇÕES DE NASOFARINGE, OLHOS, URINA  DISSEMINAÇÃO - TRATO RESPIRATÓRIO → SRE → MUCOSA BUCAL (MANCHAS DE KOPLIK) → MÁCULAS e ENANTEMAS
  • 5.  COMPLICAÇÕES - INFECÇÕES BACTERIANAS SECUNDÁRIAS - PANENCEFALITE ESCLEROSANTE SUBAGUDA 3. RUBÉOLA  AGENTE CAUSAL - FAMÍLIA Togaviridae - GÊNERO Rubivirus  TRANSMISSÃO - PESSOA – A – PESSOA; AR - 12 a 36 DIAS
  • 6.  DISSEMINAÇÃO - TRATO RESPIRATÓRIO → SANGUE → LESÕES CUTÂNEAS (4 a 7 DIAS) Obs.: RUBÉOLA CONGÊNITA - ABORTO - CATARATA, MICROCEFALIA, DEFEITOS ÓSSEOS, RETARDO MENTAL, DEFEITOS CARDÍACOS - HIPOPLASIA DE ESMALTE, PALATO FENDIDO, IRRUPÇÃO DENTAL RETARDADA
  • 7. 4. HERPESVÍRUS  AGENTE CAUSAL - SUBFAMÍLIA Alphaherperviridae - SUBFAMÍLIA Beta e Gamaherpesviridae  TIPOS DE INFECÇÃO - CICLO LÍTICO - CICLO LISOGÊNICO LATENTE ONCOGÊNICA
  • 8. 4.1 HERPES SIMPLES  TRANSMISSÃO - PELE e MUCOSAS - HSV-1: 6 MESES a 3 ANOS - HSV- 2: ADOLESCÊNCIA  DISSEMINAÇÃO - CÉLUAS EPITELIAIS → SANGUE → ÓRGÃOS ALVO → ESTÁGIOS DAS LESÕES - Obs.: MIGRAÇÃO GANGLIONAR E LATÊNCIA  MANIFESTAÇÕES CLÍNICAS → HSV-1: GENGIVOESTOMATITE HERPÉTICA
  • 9. - ERUPÇÃO VARICELIFORME DE KAPOSI - CERATOCONJUNTIVITE → HSV-2: VULVOVAGINITE HERPÉTICA; MENINGOENCEFALITE Obs.: SARCOMA DE KAPOSI (HSV-8) PERIODONTITE E HERPESVÍRUS - HSV-1, CMV, EBV - QUEDA NA RESISTÊNCIA
  • 10. 4.2 CITOMEGALIA  AGENTE CAUSAL - CITOMEGALOVÍRUS (HHV-5; Betaherpesviridae)  MANIFESTAÇÕES CLÍNICAS → INFECÇÕES PRIMÁRIAS: PROGNÓSTICO FAVORÁVEL - MANIFESTAÇÕES BUCAIS GENGIVITE ULCERAÇÕES ERITEMATOSAS NAS MUCOSAS XEROSTOMIA → INFECÇÕES CONGÊNITAS - NEUROLÓGICAS
  • 11. 4.3 MONONUCLEOSE INFECCIOSA  AGENTE CAUSAL → VÍRUS EPSTEIN-BARR (HHV-4; Betaherpesviridae)  DISSEMINAÇÃO → SALIVA (DOENÇA DO BEIJO) → LINFÓCITOS B e T  SINTOMATOLOGIA - MAL-ESTAR, DOR DE CABEÇA, FEBRE, DOR DE GARGANTA LINFADENOPATIA Obs.: LEUCOPLASIA PILOSA (AIDS)
  • 12. 5. CAXUMBA  AGENTE CAUSAL - FAMÍLIA Paramyxoviridae  TRANSMISSÃO - GOTÍCULAS DE SALIVA; FÔMITES - 12 a 36 DIAS  SINTOMATOLOGIA - FEBRE, OTALGIA, CEFALÉIA - INTUMESCIMENTO DAS PARÓTIDAS - VIREMIAS: OOFORITE, ORQUITE, HEPATITE, PANCREATITE SNS, TIREÓIDE