Content and Visual Design by Tiffany Simms This is a collection of research on big data meets autoimmune disease. Look through to read about causes, what's available, and what the future may look like.

1. Our Genes Are Not Our Destiny
The Role of Genetics, Epigenetics, and Nutrigenomics
in Autoimmunity Lifestyle Modifications

2. The Genes You Can’t Take Off: What is the Relationship between
Autoimmunity and Genetics?
• Ritchie, M., Holzinger, E., Li, R., Pendergrass, S. & Kim, D. Methods of integrating
data to uncover genotype-phenotype interactions. Nature Reviews Genetics
(2015). http://www.nature.com/nrg/journal/v16/n2/abs/nrg3868.html
• Seldin, MF. The genetics of human autoimmune disease: A perspective on
progress in the field and future directions. Journal of autoimmunity (2015).
http://www.sciencedirect.com/science/article/pii/S0896841115300330
• Smilek, D. & Clair, W. Solving the puzzle of autoimmunity: critical questions.
F1000Prime Reports 7, (2015). http://www.ncbi.nlm.nih.gov/pubmed/25750735

3. Change your Fate: What can Epigenetics do for Autoimmunity?
• Farh, K. et al. Genetic and epigenetic fine mapping of causal autoimmune disease
variants. Nature 518, 337–43 (2015).
http://www.nature.com/nature/journal/v518/n7539/full/nature13835.html
• Gupta, B. & Hawkins, D. Epigenomics of autoimmune diseases. Immunol Cell Biol
93, 271–276 (2015).
http://www.nature.com/icb/journal/v93/n3/full/icb201518a.html
• Jeffries, MA & Sawalha, AH. Autoimmune disease in the epigenetic era: how has
epigenetics changed our understanding of disease and how can we expect the
field to evolve? Expert review of clinical … (2014).
http://www.pubfacts.com/detail/25534978/Autoimmune-disease-in-the-
epigenetic-era:-how-has-epigenetics-changed-our-understanding-of-disease-a

4. Are We What We Eat Or Is What We Eat Who We Are?:
Nutrigenomics and Autoimmunity
• Ferguson, LR. Nutrigenetics, nutrigenomics and inflammatory bowel diseases. Expert review
of clinical immunology (2013). http://www.ncbi.nlm.nih.gov/pubmed/23971750
• Gibson, PR, Varney, J, Malakar, S & Muir, JG. Food Components and Irritable Bowel
Syndrome. Gastroenterology (2015). at
http://www.sciencedirect.com/science/article/pii/S0016508515001961
• Minich, D. M. & Bland, J. S. Personalized lifestyle medicine: relevance for nutrition and
lifestyle recommendations. The Scientific World Journal 2013, (2013).
http://www.ncbi.nlm.nih.gov/pubmed/23878520
• Xie, G, Li, X, Li, H & Jia, W. Toward personalized nutrition: comprehensive phytoprofiling
and metabotyping. Journal of proteome research (2013).
http://pubs.acs.org/doi/abs/10.1021/pr301222b

5. Our Genes Are Not Our
Destiny
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