Neisseria molecular mechanisms of pathogenesis pdf

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Neisseria molecular mechanisms of pathogenesis pdf

Neisseria: Molecular Mechanisms of Pathogenesis

Publisher : Caister Academic Press
Release Date :

ISBN : 1904455514
Author :
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This important book provides research scientists, advanced students, clinicians, and other
professionals with a comprehensive update on the current understanding of the molecular
mechanisms of pathogenesis in Neisseria. Neisseria gonorrhoeae and Nesseria meningitidis are
Gram-negative diplococci. N. gonorrhoeae is the causative agent of gonorrhoeae and is transmitted
via sexual contact. N. meningitidis is transmitted via respiratory droplets leading to colonization of the
nasopharynx and can cause meningitis and septicemia. The book describes the latest, up-to-date
research, theory, and clinical significance of molecular mechanisms in meningococcal disease.
Leading authorities have contributed chapters on topics such as gene expression, genomics,
biofilms, denitrification, adhesion strategies, and mechanisms of cellular invasion. A section on the
host response to neisserial infection covers inate immunity, complement, apoptosis, and acquired
immunity, while a section devoted to clinical correlation deals with vaccine development,
epidemiology, and antibiotic resistance. The book is highly recommended for microbiologists,
epidemiologists, and clinicians involved with Neisseria research or meningococcal disease, and it is a
recommended text for all microbiology libraries.
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The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed. In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine. Bio Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.

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PESTS OF SUGARCANE - BORERS BORERS 1. Early shoot borer, Chilo infuscatellus, Crambidae, Lepidoptera Symptom of damage: Deadheart in 1-3 month old crop, which can be easily pulled out, rotten portion of the straw coloured dead-heart emits an offensive odour. A number of bore holes at the base of the shoot just above the ground level. Nature of damage: Caterpillar bores into the central shoot and feeds on the internal tissue. This cause interference in the translocation of plant sap and damage the sugar storing tissues. Egg: Flat-scale like eggs are laid in 3-5 rows on the lower surface of leaves in masses of 4-100. The masses are slightly overlapping like tiles. Larva: Larva is dirty white with five dark violet longitudinal stripes and dark brown head. Pupa: Pupation takes place within the tunnel. Caterpillar before pupating makes a large exit hole in the stem and blocks the opening with silken discs. Adult: Pale greyish brown moth with black dots near the costal margin of the forewings and with white hindwings. 2. Internode borer, Chilo sacchariphagus indicus, Crambidae, Lepidoptera Symptom of damage: Internodes constricted and shortened, with a number of boreholes and fresh excreta in the nodal region. Affected tissues reddened. Nature of damage: Caterpillars attack sugarcane plants after 3 months of planting. They bore into the canes near the nodes; entry holes are plugged with excreta. Entry is generally confined to the first five internodes. Egg: Scale-like white eggs are laid by female moths in batches of 9-11, near the midribs, on leaf sheaths or on stem. Larva: White larva with four violet longitudinal stripes and light brown head. Pupa: Pupation takes place in semi-dried leaf sheath. Adult: Pale brown with white hind wings. 3. Top borer, Scirpophaga excerptalis, Pyralidae, Lepidoptera Symptom of damage: Deadheart in grownup canes, which cannot be easily pulled; deadheart reddish brown in colour; parallel row of shot holes in the emerging leaves and red tunnels in the midribs of leaves; bunchy tip due to the growth of side shoots. Nature of damage: Caterpillars are mainly found in the apical portion of the canes, boring through the growing point and down the upper joints until it reaches the sappy portion of the stem, there it feeds on the tissues and destroys the cane. They also bore into the unfolded leaves preferably into the midrib, mining its way to the base. Egg: Eggs are laid on the lower surface of top leaves in clusters particularly near midribs. The clusters are covered with buff coloured hairs. Larva :Smooth, white or cream coloured with a red coloured mid-dorsal line and yellow head. Pupa: Pupation takes place within the larval tunnel in a chamber with an exit hole constructed by the caterpillar. Adult: White coloured moth (with a buff coloured anal tuft in the abdominal tip of female).

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During this webinar, Anand Bagmar demonstrates how AI tools such as ChatGPT can be applied to various stages of the software development life cycle (SDLC) using an eCommerce application case study. Find the on-demand recording and more info at https://applitools.info/b59 Key takeaways: • Learn how to use ChatGPT to add AI power to your testing and test automation • Understand the limitations of the technology and where human expertise is crucial • Gain insight into different AI-based tools • Adopt AI-based tools to stay relevant and optimize work for developers and testers * ChatGPT and OpenAI belong to OpenAI, L.L.C.

Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...

Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...

Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...

12 Ways to Increase Your Influence at Work

12 Ways to Increase Your Influence at Work

12 Ways to Increase Your Influence at Work

ChatGPT webinar slides

ChatGPT webinar slides

ChatGPT webinar slides

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More than Just Lines on a Map: Best Practices for U.S Bike Routes

More than Just Lines on a Map: Best Practices for U.S Bike Routes

More than Just Lines on a Map: Best Practices for U.S Bike Routes

Project for Public Spaces & National Center for Biking and Walking

Has your project been caught in a storm of deadlines, clashing requirements, and the need to change course halfway through? If yes, then check out how the administration team navigated through all of this, relocating 160 people from 3 countries and opening 2 offices during the most turbulent time in the last 20 years. Belka Games’ Chief Administrative Officer, Katerina Rudko, will share universal approaches and life hacks that can help your project survive unstable periods when there seem to be too many tasks and a lack of time and people.

Ride the Storm: Navigating Through Unstable Periods / Katerina Rudko (Belka G...

Ride the Storm: Navigating Through Unstable Periods / Katerina Rudko (Belka G...

Ride the Storm: Navigating Through Unstable Periods / Katerina Rudko (Belka G...

DevGAMM Conference

Barbie - Brand Strategy Presentation

According to the latest State of the American Manager report from Gallup, employees who have regular meetings with their managers are almost three times as likely to be engaged as those who don’t. These regular check-ins keep managers and employees in sync and aligned. Want to see better manager/employee relationships in your organisation? Then make an all-in commitment to 1:1 meetings. Not sure how? You’ve come to the right place. In this webinar with Jamie Resker, Founder and Practice Leader for Employee Performance Solutions (EPS), and Teala Wilson, Talent Management Consultant at Saba Software, you’ll get the inside track on how to hold effective 1:1 meetings, including tips for getting managers on board. • Go beyond discussing the status of everyday work to higher level topics, including recognition, performance, development, and career aspirations • Learn how to decide meeting frequency, what to cover, as well as roles and responsibilities of the manager and employee • Understand how managers can build trust and make it comfortable for employees to provide upward feedback • Unite your organisation with a unified approach to 1:1 meetings Join us for this 1-hour webinar to get practical tips for building better manager-employee relationships with intention and purpose. About the Speakers Jamie Resker - Founder and Practice Leader for Employee Performance Solutions (EPS) Jamie Resker, Practice Leader and Founder of Employee Performance Solutions, is a recognized innovator in performance management. She is the originator of the-the Performance Continuum Feedback Method® and Conversations to Optimize Employee Performance training program; tools and training that reshape communications between managers and employees to drive and align performance. Jamie is on the faculty for the Northeast Human Resources Association, is a contributor to Halogen Software's Talent Space Blog, and is an editorial advisory board member for HR Examiner. Teala Wilson - Senior Consultant, Strategic Services, Saba Software Teala is a Talent Management Consultant at Halogen Software, now a part of Saba Software. She has worked with teams on a national and global level supporting human resources in areas such as performance management, recruitment, employee benefit programs, training and talent development, workforce planning and internal communications. Teala also has a personal passion for visual arts and design. Want to learn more? Join us for an upcoming Product Tour! http://bit.ly/2yitfqu

Good Stuff Happens in 1:1 Meetings: Why you need them and how to do them well

Good Stuff Happens in 1:1 Meetings: Why you need them and how to do them well

Good Stuff Happens in 1:1 Meetings: Why you need them and how to do them well

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Content Methodology: A Best Practices Report (Webinar)

Content Methodology: A Best Practices Report (Webinar)

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Social Media Marketing Trends 2024 // The Global Indie Insights

Social Media Marketing Trends 2024 // The Global Indie Insights

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Trends In Paid Search: Navigating The Digital Landscape In 2024

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ChatGPT and the Future of Work - Clark Boyd

ChatGPT and the Future of Work - Clark Boyd

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Beginners Guide to TikTok for Search - Rachel Pearson - We are Tilt __ Bright...

Beginners Guide to TikTok for Search - Rachel Pearson - We are Tilt __ Bright...

Beginners Guide to TikTok for Search - Rachel Pearson - We are Tilt __ Bright...

Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...

Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...

Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...

12 Ways to Increase Your Influence at Work

12 Ways to Increase Your Influence at Work

12 Ways to Increase Your Influence at Work

ChatGPT webinar slides

ChatGPT webinar slides

ChatGPT webinar slides

More than Just Lines on a Map: Best Practices for U.S Bike Routes

More than Just Lines on a Map: Best Practices for U.S Bike Routes

More than Just Lines on a Map: Best Practices for U.S Bike Routes

Ride the Storm: Navigating Through Unstable Periods / Katerina Rudko (Belka G...

Ride the Storm: Navigating Through Unstable Periods / Katerina Rudko (Belka G...

Ride the Storm: Navigating Through Unstable Periods / Katerina Rudko (Belka G...

Barbie - Brand Strategy Presentation

Good Stuff Happens in 1:1 Meetings: Why you need them and how to do them well

Good Stuff Happens in 1:1 Meetings: Why you need them and how to do them well

Good Stuff Happens in 1:1 Meetings: Why you need them and how to do them well

Neisseria molecular mechanisms of pathogenesis pdf

1. Neisseria: Molecular Mechanisms of Pathogenesis

2. Publisher : Caister Academic Press Release Date :

3. ISBN : 1904455514 Author : Download Here http://eap-books.club/readonline/?item=1904455514&lan=en

4. This important book provides research scientists, advanced students, clinicians, and other professionals with a comprehensive update on the current understanding of the molecular mechanisms of pathogenesis in Neisseria. Neisseria gonorrhoeae and Nesseria meningitidis are Gram-negative diplococci. N. gonorrhoeae is the causative agent of gonorrhoeae and is transmitted via sexual contact. N. meningitidis is transmitted via respiratory droplets leading to colonization of the nasopharynx and can cause meningitis and septicemia. The book describes the latest, up-to-date research, theory, and clinical significance of molecular mechanisms in meningococcal disease. Leading authorities have contributed chapters on topics such as gene expression, genomics, biofilms, denitrification, adhesion strategies, and mechanisms of cellular invasion. A section on the host response to neisserial infection covers inate immunity, complement, apoptosis, and acquired immunity, while a section devoted to clinical correlation deals with vaccine development, epidemiology, and antibiotic resistance. The book is highly recommended for microbiologists, epidemiologists, and clinicians involved with Neisseria research or meningococcal disease, and it is a recommended text for all microbiology libraries. Download Here http://eap-books.club/readonline/?item=1904455514&lan=en

5. Download Here http://eap- books.club/readonline/?item=1904455514&lan=en Powered by TCPDF (www.tcpdf.org)