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摄入维生素D和1型糖尿病的风险:对观察性研究的荟萃分析。
摘要
维生素D据称对1型糖尿病有保护作用。然而,观察性研究的结果并不一致。我们通过对观察性研究进行荟萃分析来检查这两者
之间的关联。通过于2013年6月搜索多个数据库查找包括病例对照和队列研究在内的相关研究。使用固定或随机效应模型来计算
汇总风险估计。我们明确了早年摄入维生素D的八项研究(两项队列研究和六项病例对照研究),以及妊娠期母体摄入维生素D
的三项研究(两项队列研究和一项病例对照研究)。早年补充维生素D补充与不补充维生素D的1型糖尿病合并比值比为0.71(95
%置信区间[CI],0.51-0.98)。病例对照亚组分析中也呈现类似结果,但队列亚组分析并未显示此结果。妊娠期母体摄入维生素
D的合并比值比为0.95(95%CI,0.66-1.36)。综上所述,早年摄入维生素D可能与降低1型糖尿病风险相关。然而,并没有足够
的证据表明母体摄入维生素D与胎儿1型糖尿病风险之间的联系。
------------------------
我们是医学图书馆馆员,我们正在进行一项探索非英语医学研究文章全球知名度的实验。
本摘要的翻译由经认证的翻译人员完成。完整开放获取文章的PubMed引用和链接可在这里
找到https://www.ncbi.nlm.nih.gov/pubmed/24036529。 请在下面输入您对本项
目及译文质量的意见(如果您是母语人士)。
- 科罗拉多大学健康科学图书馆,Lilian Hoffecker 和 Dana Abbey。
Vitamin D intake and risk of type 1 diabetes: a meta-analysis of observational studies.
Abstract
Vitamin D is suggested to have protective effects against type 1 diabetes. However, the results from observational studies have been inconsistent.
We aimed to examine their association by conducting a meta-analysis of observational studies. Multiple databases were searched in June 2013 to
identify relevant studies including both case-control and cohort studies. Either a fixed- or random-effects model was used to calculate the pooled
risk estimate. We identified eight studies (two cohort studies and six case-control studies) on vitamin D intake during early life and three studies
(two cohort studies and one case-control study) on maternal vitamin D intake during pregnancy. The pooled odds ratio for type 1 diabetes
comparing vitamin D supplementation with non-supplementation during early life was 0.71 (95% confidence interval [CI], 0.51-0.98). Similar
results were observed in the case-control subgroup analysis but not in the cohort subgroup analysis. The pooled odds ratio with maternal intake
of vitamin D during pregnancy was 0.95 (95% CI, 0.66-1.36). In conclusion, vitamin D intake during early life may be associated with a reduced risk
of type 1 diabetes. However, there was not enough evidence for an association between maternal intake of vitamin D and risk of type 1 diabetes
in the offspring.
_____________
We are medical librarians conducting an experiment to understand the global visibility of non-English medical research articles. The translation
for this abstract was performed by a certified translator. The PubMed citation and link to the whole open access article can be found here
https://www.ncbi.nlm.nih.gov/pubmed/24036529. Please feel free to add your comments below on the project and, if you are a native-speaker,
on the quality of the translation.
--Lilian Hoffecker and Dana Abbey, Health Sciences Library, University of Colorado.

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ﻲﻓ نﯾﺳﻧﺗوﯾﺟﻧأ-نﯾﻧﯾر مﺎظﻧ رﺎﺻﺣﻟ ﻰﻠﻛﻟاو ﺔﯾوﻣدﻟا ﺔﯾﻋوﻷاو بﻠﻘﻟا لﺋﺎﺻﺣ   ﺔﻛﺑﺷﺑ ﻲﺟﮭ...ﻲﻓ نﯾﺳﻧﺗوﯾﺟﻧأ-نﯾﻧﯾر مﺎظﻧ رﺎﺻﺣﻟ ﻰﻠﻛﻟاو ﺔﯾوﻣدﻟا ﺔﯾﻋوﻷاو بﻠﻘﻟا لﺋﺎﺻﺣ   ﺔﻛﺑﺷﺑ ﻲﺟﮭ...
ﻲﻓ نﯾﺳﻧﺗوﯾﺟﻧأ-نﯾﻧﯾر مﺎظﻧ رﺎﺻﺣﻟ ﻰﻠﻛﻟاو ﺔﯾوﻣدﻟا ﺔﯾﻋوﻷاو بﻠﻘﻟا لﺋﺎﺻﺣ ﺔﻛﺑﺷﺑ ﻲﺟﮭ...
 
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:ﺎﺑوروأ ﻲﻓ ﺔﯾﺿﯾﻷا ﺔﯾﺣﺎﻧﻟا نﻣ ﺔﯾﺣﺻﻟا ﺔﻧﻣﺳﻟاو ﻲﺋاذﻐﻟا لﯾﺛﻣﺗﻟا ﺔﻣز...
 
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ﺔﻣوﺎﻘﻣﺑ ﮫﺗﻠﺻو (NAFLD) لوﺣﻛﻟا ﻲﻓ طارﻓﻹا نﻋ مﺟﺎﻧﻟا رﯾﻏ ﻲﻧھدﻟا دﺑﻛﻟا ضرﻣ بﻠﻘﻟا ض...ﺔﻣوﺎﻘﻣﺑ ﮫﺗﻠﺻو (NAFLD) لوﺣﻛﻟا ﻲﻓ طارﻓﻹا نﻋ مﺟﺎﻧﻟا رﯾﻏ ﻲﻧھدﻟا دﺑﻛﻟا ضرﻣ بﻠﻘﻟا ض...
ﺔﻣوﺎﻘﻣﺑ ﮫﺗﻠﺻو (NAFLD) لوﺣﻛﻟا ﻲﻓ طارﻓﻹا نﻋ مﺟﺎﻧﻟا رﯾﻏ ﻲﻧھدﻟا دﺑﻛﻟا ضرﻣ بﻠﻘﻟا ض...
 
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