Meconium aspiration syndrome

1. MECONIUM ASPIRATION
SYNDROME (MAS)

2. MECONIUM ASPIRATION SYNDROME (MAS)
 AMNIOTIC FLUID- The amniotic fluid is the
protective liquid contained by the amniotic sac of a
gravid amniote.
 This fluid serves as a cushion for the growing fetus,
but also serves to facilitate the exchange of
nutrients, water, and biochemical products between
mother and fetus.

3. Contd…….
 MECONIUM - Meconium is the earliest stool of a infant.
 Unlike later feces, meconium is composed of materials ingested during the time the
infant spends in the uterus: intestinal epithelial cells, lanugo, mucus, amniotic fluid,
bile and water.

4. INTRODUCTION
 Neonates born to mothers with thick and thin meconium stained
liquor can aspirate meconium into lungs and develop respiratory
distress. This is known as meconium aspiration syndrome.
 Aspiration can be occur in utero, during birth or immediately after
birth.

5. Contd………
Thin meconium can cause chemical pneumonitis.
Thick meconium aspiration can block large and small
airways. That can cause atelectasis and emphysema.
Presence of atelectasis and emphysema can lead to
respiratory failure.

6. WHAT IS ATELECTASIS AND EMPHYSEMA?
Find out what is ATELECTASIS AND EMPHYSEMA?

7. Definition
 Meconium aspiration syndrome occurs when a newborn breathes a mixture of
meconium and amniotic fluid into the lungs around the time of delivery.
 Meconium aspiration syndrome, a leading cause of severe illness and death in
the newborn,

8. Pathophysiology

9. CLINICAL FEATURES
Usually occurs in post mature and small-for –dates babies.
These babies usually develop respiratory distress in first 24 hrs
of life, if untreated it can lead to respiratory distress.
Pneumothorax,
Air leak syndrome ( pneumopericardium, pneumomediastinum)
Persistent pulmonary hypertension.
Chest X ray shows bilateral pneumonia and air leak syndrome.

10. MANAGEMENT
 OROPHARYNGEAL SUCTION before the delivery of shoulder and
 immediately after endotracheal intubation and suctions needs to
be done.
 Oxygen therapy.
 Antibiotic management .