1. Transcriptomics is the study of the
transcriptome—the complete set of RNA
transcripts that are produced by the genome,
under specific circumstances or in a specific
cell—using high-throughput methods, such as
microarray analysis.
Transcriptomics
2. Transcriptome
The transcriptome is the set of all
RNA molecules,
including mRNA, rRNA, tRNA, and
other non-coding
RNA transcribed in one cell or a
population of cells.
4.
Cancer Transcriptomics
Oncogenomics is a relatively new
sub-field of genomics that applies
high throughput technologies to
characterize genes associated with
cancer.
5.
Transcriptome Analysis &
Gene Expression
• Transcriptome as Key Players in Gene
Expression.
• Gene expression analysis experiments
can focus on a subset of relevant target
genes. The location of gene and relative
distances between genes on a
chromosome can be determined through
Sequence mapping.
6.
Exploring Transcriptome
While exploring the complexity of the Transcriptome, the
basic protocol of the identification of long stress-induced
non-coding transcripts is followed. Non-coding RNAs
(ncRNAs) are functional RNA molecules that are
transcribed from DNA but are not translated into
proteins. Functional Impact of Non-Coding RNA
(ncRNA) involves regulation of gene expression at the
transcriptional and post-transcriptional level.
7.
Human Transcriptomics
Human Transcriptome study is a part of Human
Genome Project which is an international
scientific research project with the goal of
determining the sequence of chemical base pairs
which make up human Transcriptome and of
identifying and mapping all of the genes of the
human genome from both a physical and
functional standpoint. It includes all the aspects
of Transcription in Human Prokaryotes and
Transcription in Human Eukaryotes.
8.
RNA editing is a molecular process through which
some cells can make discrete changes to specific
nucleotide sequences within a RNA molecule after
it has been generated by RNA polymerase. RNA
editing has been observed in the RNA sequences of
viruses, archaea and prokaryotes.
9.
Transcriptomics & Proteomics in
Plants
In the research, either microarray or
RNAseq based datasets is used
forTranscriptome Analysis of
Agricultural Plants To clarify the
phylogeny of green plants,
sequences from the plastid genome
are used which is termed as Plant
Phylogenomics
11.
Expression Profiling
Gene expression profiling simultaneously compares
the expression levels of many genes between two or
more sample types. Gene expression profiling
provides valuable insight into the role of differential
gene expression in normal biological and disease
processes
12.
Transcriptomics and Proteomics of
Microorganisms describe the roles of
transcriptome and proteome in all the
microorganisms like bacteria, fungi and
viruses. To understand the phenomenon
behind a viral infection
Transcriptomics & Proteomics in
Microorganisms