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Mendel's Law and Inheritance
1.
© Boardworks Ltd
20041 of 36 KS4 Biology Inheritance
2.
© Boardworks Ltd
20042 of 36 Inheritance Contents All about alleles Homozygous cross Using a test cross Co-dominance Heterozygous cross
3.
© Boardworks Ltd
20043 of 36 the definition of certain genetic terms, Inheritance introduction To understand how inheritance works you need to know: and how to use genetic crosses to determine the characteristics of offspring. In this unit, petal colour is used to show how characteristics are inherited in offspring.
4.
© Boardworks Ltd
20044 of 36 © Boardworks Ltd 2004 Homologous chromosomes In all living things, characteristics are passed on in the chromosomes that offspring inherit from their parents. Chromosomes are matched in pairs that contain one chromosome inherited from each parent. So are the genes in a matching pair of chromosomes exactly the same? chromosome from female parent chromosome from male parent
5.
© Boardworks Ltd
20045 of 36 Each chromosome may have a different version of a gene. Different versions of a gene, that code for different versions of a characteristic, are called alleles. The chromosomes in a matching pair contain the same type of genes that code for the same characteristics. Different versions of genes version for yellow petals version for red petals gene for petal colour gene for petal colour
6.
© Boardworks Ltd
20046 of 36 Pairs of alleles – homozygous If the alleles in a matching pair are the same, they are called homozygous alleles. allele for yellow petals allele for yellow petals allele for red petals allele for red petals What colour are the flowers with these homozygous pairs of alleles? (Click twice on each bud to reveal the flower; click again to close them.)
7.
© Boardworks Ltd
20047 of 36 Pairs of alleles – heterozygous If the alleles in a matching pair are different, they are called heterozygous alleles. Which characteristic is expressed if alleles are different? allele for yellow petals allele for red petals Some alleles are dominant to other forms of a gene and will always be expressed. Which is the dominant allele in this heterozygous pair? Which is the recessive allele in this heterozygous pair? (Click twice on the bud to reveal the flower; click again to close it.)
8.
© Boardworks Ltd
20048 of 36 Representing alleles Letters are used to represent different alleles. The allele pair for each characteristic is called the genotype. What colour are flowers with the genotype Rr? A dominant allele is always a capital letter. A recessive allele is always the corresponding small letter. allele for red petals R allele for yellow petals r = =
9.
© Boardworks Ltd
20049 of 36 Genotypes and phenotypes The allele pair for each characteristic is called the genotype. The physical expression of an allele pair is the phenotype. What are the phenotypes of these genotypes? genotype: phenotype: RR Rrrr (Click twice on each bud to reveal the flowers; click again to close them.)
10.
© Boardworks Ltd
200410 of 36 Genetic jargon gene allele phenotype genotype Section of DNA that codes for a particular trait or characteristic. A different form of a gene that codes for a different version of a characteristic. A description of the pair of alleles present for a characteristic. The physical expression of the alleles. What do these genetic terms mean?
11.
© Boardworks Ltd
200411 of 36 homozygous heterozygous recessive dominant Pair of alleles that produce a characteristic that are the same, e.g. HH. Pair of alleles that produce a characteristic that are different, e.g. Hh. An allele that will only be expressed when both alleles are of this type, represented by a lower case letter. An allele that will always be expressed even when there is only one of these alleles present, represented by a capital letter. Genetic jargon What do these genetic terms mean?
12.
© Boardworks Ltd
200412 of 36 © Boardworks Ltd 2004 Matching pairs – genes
13.
© Boardworks Ltd
200413 of 36 Matching pairs – characteristics
14.
© Boardworks Ltd
200414 of 36 Contents All about alleles Homozygous cross Using a test cross Co-dominance Heterozygous cross Inheritance
15.
© Boardworks Ltd
200415 of 36 x phenotype: genotype: RR rr Homozygous means that both alleles of a gene are the same. Red is the dominant allele for these flowers, so the alleles for petal colour are: red = R , yellow = r. RR x rr – crossing homozygous parents What are the possible offspring of a cross between a homozygous red flower and a homozygous yellow flower?
16.
© Boardworks Ltd
200416 of 36 RR x rr R R r r parental genotype: gametes: rr R R Rr Rr RrRrF1 offspring genotype: RR x rr – F1 offspring What are the phenotypes of the F1 offspring? ?
17.
© Boardworks Ltd
200417 of 36 F1 genotypes: RR x rr – F1 phenotypes Rr Rr Rr Rr F1 phenotypes: (Click twice on the buds to reveal the flowers; click again to close them.) The possible offspring of a cross between two homozygous parents are always heterozygous and so the dominant characteristic is always expressed in this generation. RR x rrparental genotype:
18.
© Boardworks Ltd
200418 of 36 © Boardworks Ltd 2004 Homozygous cross activity
19.
© Boardworks Ltd
200419 of 36 Contents All about alleles Homozygous cross Using a test cross Co-dominance Heterozygous cross Inheritance
20.
© Boardworks Ltd
200420 of 36 The offspring (Rr) from the first cross (RR x rr) are called the F1 generation. What happens in a cross between these offspring? Both parent plants are now heterozygous, so the alleles in each plant are different. F1 generation genotype: phenotype: X Rr Rr Rr x Rr – crossing heterozygous parents
21.
© Boardworks Ltd
200421 of 36 Rr x Rr – F2 offspring R r R r RR Rr Rr rr What are the phenotypes of the F2 offspring? ? parental genotype: Rr x Rr R r R rgametes: F2 offspring genotype:
22.
© Boardworks Ltd
200422 of 36 Rr x Rr – F2 phenotypes F2 genotypes: RR Rr Rr rr F2 phenotypes: (Click twice on the buds to reveal the flowers; click again to close them.) In the F2 generation, 3 of the 4 possible offspring are red. Only one offspring shows the recessive phenotype. When two heterozygous parents are crossed, the possible offspring will always show a 3:1 ratio in favour of the dominant phenotype. parental genotype: Rr x Rr
23.
© Boardworks Ltd
200423 of 36 © Boardworks Ltd 2004 Heterozygous cross activity
24.
© Boardworks Ltd
200424 of 36 Contents All about alleles Homozygous cross Using a test cross Co-dominance Heterozygous cross Inheritance
25.
© Boardworks Ltd
200425 of 36 What is a test cross? A test cross allows you to find out if an organism showing a dominant characteristic is homozygous or heterozygous for the dominant allele. For example the genotype of a red flower could be: RR or Rr What could you cross a red flower with to find its genotype?
26.
© Boardworks Ltd
200426 of 36 A test cross is carried out between the flower of unknown genotype and another flower whose genotype is known. For example, a yellow flower can only have the genotype rr because it’s recessive. So the test cross is: x ? (RR or Rr) rr Carrying out a test cross
27.
© Boardworks Ltd
200427 of 36 Test cross – 2 types If the red flower is homozygous (RR) then the cross is the same as the first cross (RR x rr). All of the offspring will be heterozygous and have red petals. What about the other possible cross between a heterozygous red flower (Rr) and yellow flower (rr)? rr x ? (RR or Rr)
28.
© Boardworks Ltd
200428 of 36 Test cross offspring R r r rgametes: offspring genotype: r r R r Rr Rr rr rr What are the phenotypes of these offspring? ? Rr x rrparental genotype:
29.
© Boardworks Ltd
200429 of 36 Test cross results F2 genotypes: Rr Rr rr rr F2 phenotypes: (Click twice on the buds to reveal the flowers; click again to close them.) A cross between a heterozygous parent and a recessive parent yields different types of offspring in a 1:1 ratio. Rr x rrparental genotype:
30.
© Boardworks Ltd
200430 of 36 © Boardworks Ltd 2004 Test cross activity
31.
© Boardworks Ltd
200431 of 36 Contents All about alleles Homozygous cross Using a test cross Co-dominance Heterozygous cross Inheritance
32.
© Boardworks Ltd
200432 of 36 RR WW What is co-dominance? Sometimes two alleles are equally dominant to each other. In genetics, this is called co-dominance and means that neither allele is recessive to the other allele. How does co-dominance affect the offspring of a cross? For example, let’s assume that the red allele (R) and the white allele (W) are co-dominant: x
33.
© Boardworks Ltd
200433 of 36 RR x WW R R W W parental genotype: gametes: offspring genotype: R R W W RW RW RWRW The alleles are co-dominant so both are expressed. What will the offspring flowers look like? Co-dominance cross – offspring ?
34.
© Boardworks Ltd
200434 of 36 RW RW RW RW Co-dominance cross – phenotypes offspring genotypes: offspring phenotypes: (Click twice on the buds to reveal the flowers; click again to close them.) All the offspring flowers are pink because both the red and white alleles are expressed. RR x WWparental genotype:
35.
© Boardworks Ltd
200435 of 36 © Boardworks Ltd 2004 FLASH 5 – Blood groups Co-dominance activity
36.
© Boardworks Ltd
200436 of 36 Inheritance multiple-choice quiz
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