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Mendel & His Plants!
 Gregor Mendel bred
 pea plants and
 recorded inheritance
 patterns in the
 offspring.
Mendel’s Experiment
 Mendel   bred true-breeding plants

 When   self-fertilized, a true-breeding plant
 produces offspring identical in appearance
 to itself generation after generation.
Mendel’s Experiment
 Mendel crossed 2
 plants- 1 true-breeding
 for purple and 1 true-
 breeding for white (P
 generation)

 Hegot the following
 results: (F1
 generation)
How did he cross the plants?
Step 2: Crossing the F1 generation
 Onetrait is
 dominant

 Onetrait is
 recessive

 Ratio of Dominant :
  recessive
 12 purple: 4 white =
  3 purple: 1 white
Interest Grabber continued

           Section 11-1   Mendel’s Results




       Parents (P)                   First Generation (F1) Second Generation (F2)
       Long stems × short stems      All long            787 long: 277 short
       Red flowers × white flowers   All red             705 red: 224 white
       Green pods × yellow pods      All green           428 green: 152 yellow
       Round seeds × wrinkled seeds All round            5474 round: 1850 wrinkled
       Yellow seeds × green seeds    All yellow          6022 yellow: 2001 green


Go to
Section:
 1. In the first generation of each
  experiment, how do the characteristics of
  the offspring compare to the parents’
  characteristics?
 2. How do the characteristics of the
  second generation compare to the
  characteristics of the first generation?
Using Diagrams to show
      inheritance: Punnett Squares
 Alleles=
               P P               p p
 alternativ
 e forms of
 genes

P  =            Pp        P p

  purple
 p= white
                     P p   P p
A   B   C   D   F




1


2

3


4


5
Rules for Punnett Squares
 1. Draw a square
 Place the traits for each parent across the top
  and side (alleles)
 Bring down the alleles from the top and across
  from the side
 Write the final ratio for the genotype &
  phenotype
 Add proper vocab terms
  (homozygous/heterozygous AND Dom &
  Recessive)
Perform the following cross from the F1
  generation using a Punnett Square
Try Another!
Inheritance & Probability
 We  have been examining inheritance using
  probablilty

 Probabilities   predict AVERAGES! Not
  individuals.

 The offspring may not exactly match the
  predicted outcome (the larger the sample, the
  closer the expected values)
   25% WW (homozygous dominant)
   25% ww (homozygous recessive)
   50% Ww (heterozygous)

   75% White
   25% Black



 Will   it always turn out this way???
Two Factor/ Two Trait Crosses


 Law   of Segregation
   Alleles
          separate from one another during
   meiosis
 Law   of Independent Assortment
   Alleles
         segregate independently of one
   another (one does not depend on the other)
Two Trait Crosses
 Separatethe alleles using the FOIL
 method (kind of like a )

R     rYy

  RY    Ry    rY      ry

RrYy    x RrYy
RY    Ry   rY        ry

                       RY        Ry   rY   ry
 RrYy   x
RrYy
Two Trait Crosses
Genotypic Ratio:

1/16 RRYY          1/8 Rryy
1/8 RRYy           1/8 rrYy
1/16 RRyy          1/16 rrYY
1/8 RrYY           1/16 rryy
¼ RrYy
Phenotypic Ratio
9  Yellow Round
 3 Yellow wrinkled
 3 green round
 1 green wrinkled


 ALLHeterozygote two-trait crosses will
 result in a 9:3:3:1 ratio
Phenotypic Ratio for 2 trait crosses
9  dominant dominant
 3 dominant recessive
 3 recessive dominant
 1 recessive recessive
A Few Different Types of
             Inheritance
 http://www2.edc.org/weblabs/incompletedom/incomp
A New Kind of Inheritance
 Heterozygous
  phenotype is a
  blending of the
  recessive and
  dominant traits.
 What kind of
  inheritance?
 Incomplete Dom.
Codominance
 The  dominant AND
  the recessive are both
  expressed
 RR x rr
Multiple Alleles
 Genes with more than two alleles.
 Ex: Rabbits
  C   = full color; dominant to all other alleles
   Cch = chinchilla, partial defect in
    pigmentation, dominant to ch and c alleles
   ch Himilayan, color on certain parts of the
    body
   c= albino, no color
cchch?
                  Cc?

cc?

               chc?
Codominant Cross
 Predictthe genotypic and phenotypic ratio
 of a cross between a Full Color Rabbit
 (Cch) and a himilayan (chc).

 Genotype:25% Cch, 25%Cc, 25% chch, chc
 Phenotype: 50% Full color, 50% himilayan
Sex-Linked Genes
   Even the X and Y chromosomes code for traits
   Since males only have one X chromosome, all traits are
    expressed… even the recessive!
   This explains why males are much more likely to develop
       Colorblindness
       Hemophilia
       Duchenne Muscular Dystrophy
   These are all genes on the X
    chromosome!
Sex Linked Cross
          XH        Y


XH      X X
         H     H   XH Y



Xh     XH Xh       XhY
X-Inactivation
 How many X chromosomes do females
  have?
 How many X chromosomes do males
  have?

 Why   do females need 2?

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Mendel punett squares2traitcrosses

  • 1. Mendel & His Plants!  Gregor Mendel bred pea plants and recorded inheritance patterns in the offspring.
  • 2. Mendel’s Experiment  Mendel bred true-breeding plants  When self-fertilized, a true-breeding plant produces offspring identical in appearance to itself generation after generation.
  • 3. Mendel’s Experiment  Mendel crossed 2 plants- 1 true-breeding for purple and 1 true- breeding for white (P generation)  Hegot the following results: (F1 generation)
  • 4. How did he cross the plants?
  • 5. Step 2: Crossing the F1 generation  Onetrait is dominant  Onetrait is recessive  Ratio of Dominant : recessive  12 purple: 4 white = 3 purple: 1 white
  • 6. Interest Grabber continued Section 11-1 Mendel’s Results Parents (P) First Generation (F1) Second Generation (F2) Long stems × short stems All long 787 long: 277 short Red flowers × white flowers All red 705 red: 224 white Green pods × yellow pods All green 428 green: 152 yellow Round seeds × wrinkled seeds All round 5474 round: 1850 wrinkled Yellow seeds × green seeds All yellow 6022 yellow: 2001 green Go to Section:
  • 7.  1. In the first generation of each experiment, how do the characteristics of the offspring compare to the parents’ characteristics?  2. How do the characteristics of the second generation compare to the characteristics of the first generation?
  • 8. Using Diagrams to show inheritance: Punnett Squares  Alleles= P P p p alternativ e forms of genes P = Pp P p purple  p= white P p P p
  • 9.
  • 10. A B C D F 1 2 3 4 5
  • 11. Rules for Punnett Squares  1. Draw a square  Place the traits for each parent across the top and side (alleles)  Bring down the alleles from the top and across from the side  Write the final ratio for the genotype & phenotype  Add proper vocab terms (homozygous/heterozygous AND Dom & Recessive)
  • 12. Perform the following cross from the F1 generation using a Punnett Square
  • 14. Inheritance & Probability  We have been examining inheritance using probablilty  Probabilities predict AVERAGES! Not individuals.  The offspring may not exactly match the predicted outcome (the larger the sample, the closer the expected values)
  • 15. 25% WW (homozygous dominant)  25% ww (homozygous recessive)  50% Ww (heterozygous)  75% White  25% Black  Will it always turn out this way???
  • 16. Two Factor/ Two Trait Crosses  Law of Segregation  Alleles separate from one another during meiosis  Law of Independent Assortment  Alleles segregate independently of one another (one does not depend on the other)
  • 17. Two Trait Crosses  Separatethe alleles using the FOIL method (kind of like a ) R rYy RY Ry rY ry RrYy x RrYy
  • 18. RY Ry rY ry RY Ry rY ry  RrYy x RrYy
  • 19. Two Trait Crosses Genotypic Ratio: 1/16 RRYY 1/8 Rryy 1/8 RRYy 1/8 rrYy 1/16 RRyy 1/16 rrYY 1/8 RrYY 1/16 rryy ¼ RrYy
  • 20. Phenotypic Ratio 9 Yellow Round  3 Yellow wrinkled  3 green round  1 green wrinkled  ALLHeterozygote two-trait crosses will result in a 9:3:3:1 ratio
  • 21. Phenotypic Ratio for 2 trait crosses 9 dominant dominant  3 dominant recessive  3 recessive dominant  1 recessive recessive
  • 22. A Few Different Types of Inheritance  http://www2.edc.org/weblabs/incompletedom/incomp
  • 23. A New Kind of Inheritance  Heterozygous phenotype is a blending of the recessive and dominant traits.  What kind of inheritance?  Incomplete Dom.
  • 24. Codominance  The dominant AND the recessive are both expressed  RR x rr
  • 25. Multiple Alleles  Genes with more than two alleles.  Ex: Rabbits C = full color; dominant to all other alleles  Cch = chinchilla, partial defect in pigmentation, dominant to ch and c alleles  ch Himilayan, color on certain parts of the body  c= albino, no color
  • 26. cchch? Cc? cc? chc?
  • 27. Codominant Cross  Predictthe genotypic and phenotypic ratio of a cross between a Full Color Rabbit (Cch) and a himilayan (chc).  Genotype:25% Cch, 25%Cc, 25% chch, chc  Phenotype: 50% Full color, 50% himilayan
  • 28. Sex-Linked Genes  Even the X and Y chromosomes code for traits  Since males only have one X chromosome, all traits are expressed… even the recessive!  This explains why males are much more likely to develop  Colorblindness  Hemophilia  Duchenne Muscular Dystrophy  These are all genes on the X chromosome!
  • 29. Sex Linked Cross XH Y XH X X H H XH Y Xh XH Xh XhY
  • 30. X-Inactivation  How many X chromosomes do females have?  How many X chromosomes do males have?  Why do females need 2?