2. • Pityriasis rosea is a mild inflammatory exanthem
characterized by salmon-colored thin papules
and plaques that are at first discrete but may
become confluent
• The individual patches are oval and covered
with dry epidermis, which often desquamates,
leaving scaling in the center.
3. • Starts as single herald or mother patch
• larger than succeeding lesions
• persist 1 week or longer disappears new
lesions appear for 3-8 weeks (total course of
the disease) resolves spontaneously
• Moderate pruritus may be present(during
outbreak) and mild constitutional symptoms may
occur before the onset.
• Relapses and recurrences is rare
• The incidence is highest
• between ages 15 and 40,
• in spring and autumn.
• Women than men
4. When stretched across the long axis, the scales
tend to fold across the lines of stretch hanging
curtain sign
5. Christmas tree sign.
• These are arranged so that the
long axis of the macules runs
parallel to the lines of cleavage.
• The eruption is usually
generalized, affecting chiefly
the trunk and sparing sun-
exposed surfaces.
6. • Purpuric pityriasis rosea may manifest with petechiae and
ecchymoses along Langer lines of the neck, trunk, and proximal
extremities, and may rarely be a sign of an underlying leukemia.
•
• Pityriasis rosea occurring during pregnancy
• associated with premature delivery, neonatal hypotonia, and fetal loss,
especially if the eruption occurs within the first 15 weeks of gestation.
7. Etiology
• A response to a virus.
• most commonly human herpesvirus (HHV)–6 and HHV-7.
• A pityriasis rosea–like eruption may occur as a reaction to medications
8. Treatment
• Resolves spontaneously
• Most patients asymptomatic no therapy required
• Inadequate evidence for efficacy for most published treatments
• Trials
• acyclovir decrease the eruption and itching.
• In pregnant patients, given the small risk of harm to the fetus early in pregnancy,
acyclovir could be considered along with input from an obstetrician to help weigh the
risks and benefits.
• Corticosteroid lotions or creams relief itching.
• simple emollients Dryness and irritation
This is often confused for tinea corporis because it is an isolated patch with central colarette of scale mistaken for being annular.
HHV-2 and hepatitis C virus (HCV) have also been implicated in individual cases.
DDx : Pityriasis rosea may closely mimic seborrheic dermatitis, tinea corporis, secondary syphilis (macular syphilid), drug eruption, other viral exanthems, and psoriasis. In seborrheic dermatitis, the scalp and eyebrows are usually scaly; there is a predilection for the sternal and interscapular regions, as well as the flexor surfaces of the articulations, where the patches are covered with greasy scales. Tinea corporis is rarely so widespread. Tinea versicolor may also closely simulate pityriasis rosea but the individual lesions tend to be flatter and smaller. A positive potassium hydroxide (KOH) examination serves well to differentiate these last two. In macular syphilid, the lesions are of a uniform size and assume a brownish tint. Scaling and itching are absent or slight, and there is typically generalized adenopathy with mucous membrane lesions, palmoplantar lesions, positive nontreponemal and treponemal tests, and often the remains of a chancre. Because syphilis can so closely mimic pityriasis rosea and syphilis incidence is rising again, strong consideration for syphilis testing should be considered in patients with pityriasis rosea. Scabies and lichen planus may be confused with the papular type.
A pityriasis rosea–like eruption may occur as a reaction to medications such as
Ex: captopril, imatinib mesylate, interferon, ketotifen, arsenicals, gold, bismuth, clonidine, methoxypromazine, tripelennamine hydrochloride, ergotamine, lisinopril, acyclovir, lithium, adalimumab, nortriptyline, lamotrigine, rituximab, imatinib, asenapine, barbiturates, or bacille Calmette-Guérin (BCG) vaccine