NLM for Health Sciences Student Session 3 - PubMed Pt. 2

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More PubMed

What are these?
* MESH searching
* Clinical trials
Specialized Interfaces
* PubMed Health
* PubMed Central
* NCBI Bookshelf

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NLM for Health Sciences Student Session 3 - PubMed Pt. 2

  1. 1. Session Three – Exploring PubMed, Part 2
  2. 2. What is MeSH? MeSH (Medical Subject Headings) is the NLM’s controlled vocabulary thesaurus used for indexing articles citations in PubMed. Subject terms can be browsed from http://www.nlm.nih.gov/mesh/ meshhome.html
  3. 3. MeSH Searching You can begin a search of the MeSH database by selecting the link from PubMed’s webpage.
  4. 4. Familiar Interface You will see a familiar search screen similar to most NLM databases. Enter your term in to the search box and press the Search button.
  5. 5. Entering Search Terms When entering a term into the search box a selection of suggested terms will appear in the dropdown menu. Select the one you wish to use or press the Search button to start your search.
  6. 6. MeSH Search Results The search results displayed subject headings related to “headache.” Searched terms are displayed in the “Search details” box.
  7. 7. MeSH Term Display Once you have selected a term from the results list a definition (or scope note) of the subject displays. This provides a brief discussion on use of the world within the MeSH database. Below the note are Subheadings related to the term.
  8. 8. Indexing Tree Bottom of the page reveals an index tree revealing the hierarchical structure of the subject heading within MeSH. MeSH terms are arranged hierarchically by subject categories with more specific (narrower) terms arranged beneath broader terms. PubMed automatically explodes searches to include all Select an item narrower terms. to see the terms’ definition and indexing tree.
  9. 9. MeSH Term Display - One Level Up By selecting the subject heading higher on the tree, you have expanded the possible search parameters.
  10. 10. Select a subheading to then select “Add to search builder.” Select “Search PubMed” to see the results. Add Terms to Search Builder
  11. 11. First Results Set Results from MeSH search.
  12. 12. Add Terms from History Combine MeSH searches from History.
  13. 13. Second Results Set Combined terms reduce results, refines the search.
  14. 14. Clinical Trials Work that is the report of a pre-planned clinical study of the safety, efficacy, or optimum dosage schedule of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques in humans selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. While most clinical trials concern humans, this publication type may be used for clinical veterinary articles meeting the requisites for humans. Specific headings for specific types and phases of clinical trials are also available. (MeSH Database)
  15. 15. Use the Filters We are searching for Article information about distance education and nursing.
  16. 16. Different Phases •Phase I (Publication Type) Work that is the report of a pre-planned, usually controlled, clinical study of the safety and efficacy of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques based on a small number of healthy persons and conducted over the period of about a year in either the United States or a foreign country. (MeSH Database) •Phase II (Publication Type) These studies are performed on several hundred volunteers, including a limited number of patients with the target disease or disorder, and last about two years. (MeSH Database) •Phase III (Publication Type) These studies are performed on groups of patients large enough to identify clinically significant responses and usually last about three years. (MeSH Database) •Phase IV (Publication Type) Work that is a report of a planned post-marketing study of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques that have been approved for general sale after clinical trials, phases I, II, and III. These studies, conducted in the United States or a foreign country, often garner additional data about the safety and efficacy of a product. (MeSH Database)
  17. 17. The Other Database ClinicalTrials.gov is a Web-based resource that provides patients, their family members, health care professionals, researchers, and the public with easy access to information on publicly and privately supported clinical studies on a wide range of diseases and conditions.
  18. 18. Evidence Based Practice A way of providing health care that is guided by a thoughtful integration of the best available scientific knowledge with clinical expertise. This approach allows the practitioner to critically assess research data, clinical guidelines, and other information resources in order to correctly identify the clinical problem, apply the most high-quality intervention, and re-evaluate the outcome for future improvement. (MeSH Database)
  19. 19. Results for EBP Searching for articles using MESH headings “Evidence- Based Nursing” and “Myocardial Infarction”
  20. 20. PubMed Health Search for things that work!
  21. 21. What is PubMed Health? • PubMed Health provides information for consumers and clinicians on prevention and treatment of diseases and conditions. • PubMed Health specializes in reviews of clinical effectiveness research, with easy-to-read summaries for consumers as well as full technical reports. Clinical effectiveness research finds answers to the question “What works?” in medical and health care. • PubMed Health is based on systematic reviews of clinical trials. These clinical effectiveness reviews can show what treatments and prevention methods have been proven to work—and what remains unknown. • PubMed Health provides summaries and full texts of selected systematic reviews in one place. The reviews were generally published or updated from 2003. There is also information for consumers and clinicians based on those reviews.
  22. 22. What are the Resources? A search on PubMed Health runs simultaneously in PubMed. A filter is used to identify all the indexed scientific articles at the NLM that might be systematic reviews. This search includes articles from before 2003. Information partners selected by PubMed Health to contribute their clinical effectiveness information are: – Agency for Health Care Research and Quality (US) (AHRQ) – Centre for Reviews and Dissemination (CRD) – The Cochrane Collaboration (CC) – German Institute for Quality and Efficiency in Health Care (IQWiG) – National Cancer Institute (NCI) – National Institute for Health and Care Excellence guidelines program (NICE) – National Institute for Health Research (NIHR) Health Technology Assessment Programme (NIHR HTA) – Oregon Health and Science University's Drug Effectiveness Review Project (DERP) – Department of Veterans Affairs' Evidence-based Synthesis Program from the Veterans Health Administration R&D (VA ESP)
  23. 23. What is a Systematic Review? Definition: A summary of the clinical literature. A systematic review is a critical assessment and evaluation of all research studies that address a particular clinical issue. The researchers use an organized method of locating, assembling, and evaluating a body of literature on a particular topic using a set of specific criteria. A systematic review typically includes a description of the findings of the collection of research studies. The systematic review may also include a quantitative pooling of data, called a meta-analysis. Example: Scientists collected all the published studies that compared types of treatment for prostate cancer that had not spread beyond the prostate gland. They compiled the results of these studies in a comparative effectiveness review, which is a type of systematic review. (text from AHRQ)
  24. 24. Results of a Search
  25. 25. Quality of the Resources Resources from which the information is drawn, includes Systematic Reviews from PubMed.
  26. 26. More to Learn! Helpful resources provide insight into the materials provided through PubMed Health.
  27. 27. PubMed Central There are millions of “open access” articles in the PMC database.
  28. 28. Browse Titles Enter journal title and press search. If searching for all issues of a journal, including journal title changes, select “Show predecessor titles.”
  29. 29. Search for a Journal Title Here the search was conducted for the Journal of the Medical Library Association. Select the title provides a listing of all currently available volumes and issues.
  30. 30. Full text Articles Select a volume and open an article.
  31. 31. NCBI Bookshelf A collection of e-books in a variety formats. •Acrobat (.pdf) •HTML •Searchable HTML
  32. 32. Browse the Titles Browse through the title. Select the one to view the text of the book.
  33. 33. Searchable Only Some books are only searchable. Search terms are highlighted in chapters and pages of the book.
  34. 34. Search Text within a Book Text within books is searchable. Search terms are highlighted in chapters and pages of the book.
  35. 35. What’s next? In the next session we will discuss: – Daily Med – Drug Information Portal – MedlinePlus – Images from the History of Medicine – International Resources

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