Bacteria are microscopic prokaryotes that are generally spherical, rod-shaped, or spiral. They have cytoplasm and DNA surrounded by a cell membrane and cell wall. While most bacteria do not cause disease, some are pathogens that can damage tissue or release toxins. Viruses are strands of DNA or RNA surrounded by protein that can only replicate inside a host cell. Unlike bacteria, viruses are not considered living and require a host cell to reproduce. Both bacteria and viruses can cause disease in humans, but bacteria can reproduce on their own while viruses rely on host cells.