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CAMBRIDGE UNIVERSITY LIBRARY
                                MEDICAL LIBRARY




Systematic Literature Reviews:
    A 'How To' Guide

Isla Kuhn

Reader Services Librarian

Medical Library
CAMBRIDGE UNIVERSITY LIBRARY
                                                            MEDICAL LIBRARY




• how to clarify the question (or perhaps questions) on which you need to find
  literature

• selecting the databases and other resources you will need to search

• devising the most comprehensive literature search strategy so you know
  you’ve not missed any relevant studies

• keeping up to date with new information appearing between the initial search
  and write-up

• issues around management of process and results

• management of references (using software such as EndNote), and getting
  hold of the full text article
1 clinical trial.pt.          24 or/13-23                           46 exp Bed Rest/
                                                                 CAMBRIDGE UNIVERSITY LIBRARY
2 randomized.ab,ti.                                                  MEDICAL LIBRARY
                                                                    47 bed rest.mp.
                              25 exp Spine/
3 placebo.ab,ti.              26 discitis.ab,ti.                    48 or/39-47
4 dt.fs.                      27 exp Spinal Diseases/               49 24 or 38
5 randomly.ab,ti.             28 (disc adj degeneration).ab,ti. 50 12 and 49
6 trial.ab,ti.                29 (disc adj prolapse).ab,ti.         51 48 and 50
7 groups.ab,ti.               30 (disc adj herniation).ab,ti.
8 or/1-7                      31 spinal fusion.sh.
9 Animals/                    32 spinal neoplasms.sh.
10 Humans/                    33 (facet adj joints).ab,ti.
11 9 not (9 and 10)           34 intervertebral disk.sh.
12 8 not 11                   35 postlaminectomy.ab,ti.
13 dorsalgia.ab,ti.           36 arachnoiditis.ab,ti.
14 exp Back Pain/             37 (failed adj back).ab,ti.
15 exp Low Back Pain/         38 or/25-37
16 backache.ab,ti.            39 exp activities of daily living/
17 (lumbar adj pain).ab,ti.   40 activities of daily living.tw.
18 coccyx.ab,ti.              41 day to day activ$.ti,ab.
19 coccydynia.ab,ti.          42 daily activit$.ti,ab.
20 exp Sciatica/              43 ordinary activit$.ti,ab.
21 sciatica.ab,ti.            44 normal activit$.ti,ab.
22 spondylosis.ab,ti.         45 stay$ active.ti,ab.
23 lumbago.ab,ti.
What do you actually have to produce?      CAMBRIDGE UNIVERSITY LIBRARY
                                               MEDICAL LIBRARY




• http://www.prisma-statement.org/2.1.2%20-%20PRISMA%202009%20Chec
From topic to search                               CAMBRIDGE UNIVERSITY LIBRARY
                                                       MEDICAL LIBRARY




introducing the research topic

  • clarifying the question

  • setting parameters (inclusion/exclusion criteria not built into
    search?)

lose marks through sloppy references
                                 Question
                                 Keywords
                                 Synonyms
                                 MeSH / Subject Headings / sub headings
                                 Boolean Logic
                                 Truncation / wildcards
                                 Limits
From topic to search                                      CAMBRIDGE UNIVERSITY LIBRARY
                                                               MEDICAL LIBRARY




 • Topic -> question -> keywords/synonyms


Diabetes, especially the impact of patient education …..
        ”Is patient education effective in improving blood sugar control
                             in teenage diabetics?”
…………………keywords???.... synonyms???........................

     Themes?
From topic to search                                       CAMBRIDGE UNIVERSITY LIBRARY
                                                               MEDICAL LIBRARY




          ”Is patient education effecting in improving blood sugar control
                                 in teenage diabetics?”
1 – teenagers

2 – patient education

3 – blood sugar
                                              PICO ?

                                              Patient/Problem/Population
                                              Intervention
   Synonyms?
                                              Comparison
                                              Outcome

                                              (time?)
From topic to search                                 CAMBRIDGE UNIVERSITY LIBRARY
                                                         MEDICAL LIBRARY




      ”Is patient education effecting in improving blood sugar control
                            in teenage diabetics?”
1 – teenagers teens adolescents

2– patient education patient information

3 – blood sugar blood glucose hypoglycaemia hyperglycaemia
Boolean Logic                                        CAMBRIDGE UNIVERSITY LIBRARY
                                                         MEDICAL LIBRARY



  AND – to narrow the search by combining different topics

    eg

       “physiotherapy” and “stroke”


  Both terms must be present in the results.




           Physiotherapy                            Stroke
Boolean Logic                                             CAMBRIDGE UNIVERSITY LIBRARY
                                                               MEDICAL LIBRARY




OR – to broaden your search, by combining similar terms

  eg

  “exercise” or “physical activity”

Either term can be present in the resulting set of articles.




                                               Cerebral-vascular
                Stroke
                                                   Accident
Boolean Logic                                              CAMBRIDGE UNIVERSITY LIBRARY
                                                               MEDICAL LIBRARY




NOT – to restrict your search so that it does not contain a particular term

  eg

“physical therapy” not “manual therapy”



The first, but not the second, term must be present.


                  Physical                       Manual
                  Therapy                        Therapy
From topic to search                                CAMBRIDGE UNIVERSITY LIBRARY
                                                        MEDICAL LIBRARY




      ”Is patient education effecting in improving blood sugar control
                            in teenage diabetics?”
teenagers OR teens OR adolescents

AND

patient education OR patient information

AND

blood sugar OR blood glucose OR hypoglycaemia OR hyperglycaemia
Question:                    CAMBRIDGE UNIVERSITY LIBRARY
                                 MEDICAL LIBRARY




 1st theme   OR         OR        OR

                  AND

 2nd theme   OR         OR        OR

                  AND

 3rd theme   OR         OR        OR

                  AND

4th theme?   OR         OR        OR
Mind map your question?                         CAMBRIDGE UNIVERSITY LIBRARY
                                                     MEDICAL LIBRARY



synonym      synonym                   synonym                synonym

          1st                                      2nd
          theme                                    theme          synonym

synonym
                            Research
                            question

synonym
                                                                  synonym
          3rd                                      4th
          theme                                    theme
                  synonym
                                       synonym                  synonym
synonym
Truncation                     CAMBRIDGE UNIVERSITY LIBRARY
                                   MEDICAL LIBRARY



Treatment


       treat

       treats

       treating     • Treat*

       treated      • Treat?

       treater      • Treat$

       treatment

       treatments
From topic to search                                CAMBRIDGE UNIVERSITY LIBRARY
                                                        MEDICAL LIBRARY




                          Truncation / wildcards?


1 – teenagers OR teens OR adolescents

AND

2 – patient education OR patient information

AND

3 – blood sugar OR blood glucose OR hypoglycaemia OR hyperglycaemia
Task                                              CAMBRIDGE UNIVERSITY LIBRARY
                                                      MEDICAL LIBRARY




• Go to http://wok.mimas.ac.uk

• Open Web of Science

• Type a key word, and search by “topic”

   • How many hits?

• Type the keyword with some truncation (use *)

   • How many hits?
From topic to search                              CAMBRIDGE UNIVERSITY LIBRARY
                                                      MEDICAL LIBRARY




• Where in the article record do you want the terms/keywords to appear?

  • Title?

  • Abstract?

  • All/any field?



• Impact on sensitivity/specificity?
Task                                       CAMBRIDGE UNIVERSITY LIBRARY
                                               MEDICAL LIBRARY




• Go to http://wok.mimas.ac.uk

• Open Web of Science

• Type a key word, and search by “topic”

   • How many hits?

• Type a keyword and search by “title”

   • How many hits?
CAMBRIDGE UNIVERSITY LIBRARY
    MEDICAL LIBRARY
CAMBRIDGE UNIVERSITY LIBRARY
             MEDICAL LIBRARY




http://www.ncbi.nlm.nih.gov/pubmed/201
From topic to search                              CAMBRIDGE UNIVERSITY LIBRARY
                                                      MEDICAL LIBRARY




                                 MeSH


1 – teen* OR adolesce* OR "Adolescent"[Mesh]

AND

2 – patient education OR patient information OR "Patient Education as
  Topic"[Mesh]

AND

3 – blood sugar OR blood glucose OR hypoglycae* OR hyperglyca* OR
  "Blood Glucose"[Mesh] OR "Hypoglycemia"[Mesh]
From topic to search                                                   CAMBRIDGE UNIVERSITY LIBRARY
                                                                            MEDICAL LIBRARY




                           Inclusion / exclusion criterion?
teen* OR adolesce* OR "Adolescent"[Mesh]

AND

patient education OR patient information OR "Patient Education as Topic"[Mesh]

AND

blood sugar OR blood glucose OR hypoglycae* OR hyperglyca* OR "Blood Glucose"[Mesh] OR
   "Hypoglycemia"[Mesh]




      Year of publication? Humans vs Animals?
      Type of publication? Language of publication?
1 clinical trial.pt.          24 or/13-23                           46 exp Bed Rest/
                                                                 CAMBRIDGE UNIVERSITY LIBRARY
2 randomized.ab,ti.                                                  MEDICAL LIBRARY
                                                                    47 bed rest.mp.
                              25 exp Spine/
3 placebo.ab,ti.              26 discitis.ab,ti.                    48 or/39-47
4 dt.fs.                      27 exp Spinal Diseases/               49 24 or 38
5 randomly.ab,ti.             28 (disc adj degeneration).ab,ti. 50 12 and 49
6 trial.ab,ti.                29 (disc adj prolapse).ab,ti.         51 48 and 50
7 groups.ab,ti.               30 (disc adj herniation).ab,ti.
8 or/1-7                      31 spinal fusion.sh.
9 Animals/                    32 spinal neoplasms.sh.
10 Humans/                    33 (facet adj joints).ab,ti.
11 9 not (9 and 10)           34 intervertebral disk.sh.
12 8 not 11                   35 postlaminectomy.ab,ti.
13 dorsalgia.ab,ti.           36 arachnoiditis.ab,ti.
14 exp Back Pain/             37 (failed adj back).ab,ti.
15 exp Low Back Pain/         38 or/25-37
16 backache.ab,ti.            39 exp activities of daily living/
17 (lumbar adj pain).ab,ti.   40 activities of daily living.tw.
18 coccyx.ab,ti.              41 day to day activ$.ti,ab.
19 coccydynia.ab,ti.          42 daily activit$.ti,ab.
20 exp Sciatica/              43 ordinary activit$.ti,ab.
21 sciatica.ab,ti.            44 normal activit$.ti,ab.
22 spondylosis.ab,ti.         45 stay$ active.ti,ab.
23 lumbago.ab,ti.
1 clinical trial.pt.          24 or/13-23                           46 exp Bed Rest/
                                                                 CAMBRIDGE UNIVERSITY LIBRARY
2 randomized.ab,ti.                                                  MEDICAL LIBRARY
                                                                    47 bed rest.mp.
                              25 exp Spine/
3 placebo.ab,ti.              26 discitis.ab,ti.                    48 or/39-47
4 dt.fs.                      27 exp Spinal Diseases/               49 24 or 38
5 randomly.ab,ti.             28 (disc adj degeneration).ab,ti. 50 12 and 49
6 trial.ab,ti.                29 (disc adj prolapse).ab,ti.         51 48 and 50
7 groups.ab,ti.               30 (disc adj herniation).ab,ti.
8 or/1-7                      31 spinal fusion.sh.
9 Animals/                    32 spinal neoplasms.sh.
10 Humans/                    33 (facet adj joints).ab,ti.
11 9 not (9 and 10)           34 intervertebral disk.sh.
12 8 not 11                   35 postlaminectomy.ab,ti.
13 dorsalgia.ab,ti.           36 arachnoiditis.ab,ti.
14 exp Back Pain/             37 (failed adj back).ab,ti.
15 exp Low Back Pain/         38 or/25-37
16 backache.ab,ti.            39 exp activities of daily living/
17 (lumbar adj pain).ab,ti.   40 activities of daily living.tw.
18 coccyx.ab,ti.              41 day to day activ$.ti,ab.
19 coccydynia.ab,ti.          42 daily activit$.ti,ab.
20 exp Sciatica/              43 ordinary activit$.ti,ab.
21 sciatica.ab,ti.            44 normal activit$.ti,ab.
22 spondylosis.ab,ti.         45 stay$ active.ti,ab.
23 lumbago.ab,ti.
CAMBRIDGE UNIVERSITY LIBRARY
                                                                                        MEDICAL LIBRARY




Advice to rest in bed versus advice to stay active for acute
low-back pain and sciatica


The objective of this review is to determine the effects of advice to rest in bed or stay active for patients
   with acute low-back pain or sciatica.
The following comparisons will be made:
    •    Bed rest versus staying active
    •    Bed rest versus other treatments (besides staying active)
    •    Shorter periods of bed rest versus longer periods of bed rest
    •    Staying active versus other treatments (besides bed rest)
    •    Comparison between different forms of advice to stay active (e.g. avoiding bedrest, staying active)
http://mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD007612/pdf_fs.html
From topic to search:                    CAMBRIDGE UNIVERSITY LIBRARY
                                             MEDICAL LIBRARY
same strategy, different words

Moving from one database to another…..
From topic to search:                                                            CAMBRIDGE UNIVERSITY LIBRARY

    same strategy, different words                                                       MEDICAL LIBRARY



    Medline (via OVID)                                              Embase (via OVID)
    1 Epidemiologic studies/                                        1 Clinical study/
    2 Exp case control studies/                                     2 Case control study
    3 Exp cohort studies/                                           3 Family study/
    4 Case control.tw.                                              4 Longitudinal study/
    5 (cohort adj (study or studies)).tw.                           5 Retrospective study/
    6 Cohort analy$.tw.                                             6 Prospective study/
    7 (Follow up adj (study or studies)).tw.                        7 Randomized controlled trials/
    8 (observational adj (study or studies)).tw.                    8 6 not 7
    9 Longitudinal.tw.                                              9 Cohort analysis/
    10 Retrospective.tw.                                            10 (Cohort adj (study or studies)).mp.
    11 Cross sectional.tw.                                          11 (Case control adj (study or studies)).tw.
    12 Cross-sectional studies/                                     12 (follow up adj (study or studies)).tw.
    13 Or/1-12                                                      13 (observational adj (study or studies)).tw.
                                                                    14 (epidemiologic$ adj (study or studies)).tw.
                                                                    15 (cross sectional adj (study or studies)).tw.
                                                                    16 Or/1-5,8-15

•     http://www.sign.ac.uk/methodology/filters.html Observational Study Filters
From topic to search:                                                            CAMBRIDGE UNIVERSITY LIBRARY

same strategy, different words                                                       MEDICAL LIBRARY



Medline (via OVID)                                           Medline (via Pubmed)
1 Epidemiologic studies/                                     #1 “Epidemiologic studies”[Mesh]
2 Exp case control studies/                                  #2 “case control studies”[Mesh]
3 Exp cohort studies/                                        #3 “cohort studies”[Mesh]
4 Case control.tw.                                           #4 Case control[Text Word]
5 (cohort adj (study or studies)).tw.                        #5 (cohort stud*))[Text Word]
6 Cohort analy$.tw.                                          #6 Cohort analy*[Text Word]
7 (Follow up adj (study or studies)).tw.                     #7 (Follow up AND (study or studies))[Text Word]
8 (observational adj (study or studies)).tw.                 #8 (observational AND (study or studies))[Text
9 Longitudinal.tw.                                           Word]
10 Retrospective.tw.                                         #9 Longitudinal[Text Word]
11 Cross sectional.tw.                                       #10 Retrospective[Text Word]
12 Cross-sectional studies/                                  #11 Cross sectional[Text Word]
13 Or/1-12                                                   #12 “Cross-sectional studies”[Mesh]
                                                             #13 #1 OR #2 OR #3 OR #4 OR #5 OR #6 OR
                                                             #7 OR #8 OR #9 OR #10 OR #11 OR #12


•   http://www.sign.ac.uk/methodology/filters.html Observational Study Filters
Keywords                                       CAMBRIDGE UNIVERSITY LIBRARY
                                                   MEDICAL LIBRARY



introducing the research topic

reviewing relevant literature
  • identifying keywords and synonyms and MeSH

  • structuring your search strategy with boolean logic



References
  • DON’T plagiarise!

  • Don’t lose marks through sloppy references
Sensitivity vs Specificity   CAMBRIDGE UNIVERSITY LIBRARY
                                 MEDICAL LIBRARY
Sensitivity vs Specificity   CAMBRIDGE UNIVERSITY LIBRARY
                                 MEDICAL LIBRARY
Sensitivity vs Specificity   CAMBRIDGE UNIVERSITY LIBRARY
                                 MEDICAL LIBRARY
CAMBRIDGE UNIVERSITY LIBRARY
                                                               MEDICAL LIBRARY


introducing the research topic
reviewing relevant literature

Identify relevant sources (and then search them!)
                                 • http://www.lib.cam.ac.uk/electronicresources/
   databases?
                                 • Google? Search by Organisation
   websites?
   hand searching?               • Which journals are key to your work?

   snowballing?                  • WoK or Scopus

   books?                        • LibrarySearch or COPAC or GoogleBooks
   grey literature?              • Google: blog search; SIGLE;
                                   conference proceedings
   ongoing trials?
                                 • Trials registers
CAMBRIDGE UNIVERSITY LIBRARY
                                                                  MEDICAL LIBRARY


introducing the research topic
                                                    CASP http://www.casp-uk.net
reviewing relevant literature

Identify relevant sources (and then search them!)   “How to read a paper” Trish
                                                    Greenhalgh
References & PDFs                                   WB 18.343 – in the Medical Library
                                                    or http://tinyurl.com/bmj-trish
   • Critically appraising
                                                         Zotero
                                                         Mendeley
   • managing                                            EndnoteWeb
                                                         Endnote
   • storing                                             Reference Manager
                                                         RefWorks
   • using them (cite while you write)                   Papers

   • Data extraction                                     Pdf xchange

                                                         Prisma
CAMBRIDGE UNIVERSITY LIBRARY
                                                                   MEDICAL LIBRARY


introducing the research topic

reviewing relevant literature

Identify relevant sources (and then search them!)

References

Keeping up to Date
   • alerts
                                                    Email alerts
   • journal TOCs                                   RSS fees

   • citation tracking
CAMBRIDGE UNIVERSITY LIBRARY
                                                                      MEDICAL LIBRARY


introducing the research topic

reviewing relevant literature

Identify relevant sources (and then search them!)

References

Keeping up to Date

Management of process and results – more info on data management

                        •       What is the data you need to record?
                        •       Where will you record it? Where will you store it?
                        •       How will you record it?
                        •       How will you share it?

                        When should all this start?
CAMBRIDGE UNIVERSITY LIBRARY
                                                                       MEDICAL LIBRARY


introducing the research topic

reviewing relevant literature

Identify relevant sources (and then search them!)

References

Keeping up to Date

Management of process and results

Writing Up
   • what did you actually do?

   • and where did you do it? (750 words?)
                                  •   Search log/diary
                                  •   Results matrix
                                  •   Tidying up your strategy
                                  •   What did you find, where?
                                  •   Explicit criterion = reproducable methodology
CAMBRIDGE UNIVERSITY LIBRARY
                                                                   MEDICAL LIBRARY




                                                  http://www.bmj.com/content/328/7446/991.full.pdf



http://jech.bmj.com/content/61/12/1069.full.pdf
Books that might help                                                                           CAMBRIDGE UNIVERSITY LIBRARY
                                                                                                      MEDICAL LIBRARY


                        •   http://search.lib.cam.ac.uk/?itemid=|cambrdgedb|1258728




                                                             http://search.lib.cam.ac.uk/?itemid=|cambrdgedb|317470




http://search.lib.cam.ac.uk/?itemid=|cambrdgedb|4750307




                              http://search.lib.cam.ac.uk/?itemid=|cambrdgedb|4850812
Stopping                                                 CAMBRIDGE UNIVERSITY LIBRARY
                                                             MEDICAL LIBRARY




• Repetition

• Change in ratio of “good” : ”bad” articles retrieved

• Boundaries/Parameters?



• Databases are not infinite:

  • if your strategy is good enough,
    and your current awareness strategy is in place, trust it, and stop.
CAMBRIDGE UNIVERSITY LIBRARY
    MEDICAL LIBRARY
Help!                                    CAMBRIDGE UNIVERSITY LIBRARY
                                             MEDICAL LIBRARY




Isla Kuhn
 Reader Services Librarian

 Medical Library

 Box 111

 Addenbrooke’s Hospital


 email: ilk21@cam.ac.uk

 phone: (01223) (3)36750

 web: http://library.medschl.cam.ac.uk


                                              Thank you.

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Systematic review how to - michaelmas 2012

  • 1. CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY Systematic Literature Reviews: A 'How To' Guide Isla Kuhn Reader Services Librarian Medical Library
  • 2. CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY • how to clarify the question (or perhaps questions) on which you need to find literature • selecting the databases and other resources you will need to search • devising the most comprehensive literature search strategy so you know you’ve not missed any relevant studies • keeping up to date with new information appearing between the initial search and write-up • issues around management of process and results • management of references (using software such as EndNote), and getting hold of the full text article
  • 3. 1 clinical trial.pt. 24 or/13-23 46 exp Bed Rest/ CAMBRIDGE UNIVERSITY LIBRARY 2 randomized.ab,ti. MEDICAL LIBRARY 47 bed rest.mp. 25 exp Spine/ 3 placebo.ab,ti. 26 discitis.ab,ti. 48 or/39-47 4 dt.fs. 27 exp Spinal Diseases/ 49 24 or 38 5 randomly.ab,ti. 28 (disc adj degeneration).ab,ti. 50 12 and 49 6 trial.ab,ti. 29 (disc adj prolapse).ab,ti. 51 48 and 50 7 groups.ab,ti. 30 (disc adj herniation).ab,ti. 8 or/1-7 31 spinal fusion.sh. 9 Animals/ 32 spinal neoplasms.sh. 10 Humans/ 33 (facet adj joints).ab,ti. 11 9 not (9 and 10) 34 intervertebral disk.sh. 12 8 not 11 35 postlaminectomy.ab,ti. 13 dorsalgia.ab,ti. 36 arachnoiditis.ab,ti. 14 exp Back Pain/ 37 (failed adj back).ab,ti. 15 exp Low Back Pain/ 38 or/25-37 16 backache.ab,ti. 39 exp activities of daily living/ 17 (lumbar adj pain).ab,ti. 40 activities of daily living.tw. 18 coccyx.ab,ti. 41 day to day activ$.ti,ab. 19 coccydynia.ab,ti. 42 daily activit$.ti,ab. 20 exp Sciatica/ 43 ordinary activit$.ti,ab. 21 sciatica.ab,ti. 44 normal activit$.ti,ab. 22 spondylosis.ab,ti. 45 stay$ active.ti,ab. 23 lumbago.ab,ti.
  • 4. What do you actually have to produce? CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY • http://www.prisma-statement.org/2.1.2%20-%20PRISMA%202009%20Chec
  • 5. From topic to search CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY introducing the research topic • clarifying the question • setting parameters (inclusion/exclusion criteria not built into search?) lose marks through sloppy references Question Keywords Synonyms MeSH / Subject Headings / sub headings Boolean Logic Truncation / wildcards Limits
  • 6. From topic to search CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY • Topic -> question -> keywords/synonyms Diabetes, especially the impact of patient education ….. ”Is patient education effective in improving blood sugar control in teenage diabetics?” …………………keywords???.... synonyms???........................ Themes?
  • 7. From topic to search CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY ”Is patient education effecting in improving blood sugar control in teenage diabetics?” 1 – teenagers 2 – patient education 3 – blood sugar PICO ? Patient/Problem/Population Intervention Synonyms? Comparison Outcome (time?)
  • 8. From topic to search CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY ”Is patient education effecting in improving blood sugar control in teenage diabetics?” 1 – teenagers teens adolescents 2– patient education patient information 3 – blood sugar blood glucose hypoglycaemia hyperglycaemia
  • 9. Boolean Logic CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY AND – to narrow the search by combining different topics eg “physiotherapy” and “stroke” Both terms must be present in the results. Physiotherapy Stroke
  • 10. Boolean Logic CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY OR – to broaden your search, by combining similar terms eg “exercise” or “physical activity” Either term can be present in the resulting set of articles. Cerebral-vascular Stroke Accident
  • 11. Boolean Logic CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY NOT – to restrict your search so that it does not contain a particular term eg “physical therapy” not “manual therapy” The first, but not the second, term must be present. Physical Manual Therapy Therapy
  • 12. From topic to search CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY ”Is patient education effecting in improving blood sugar control in teenage diabetics?” teenagers OR teens OR adolescents AND patient education OR patient information AND blood sugar OR blood glucose OR hypoglycaemia OR hyperglycaemia
  • 13. Question: CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY 1st theme OR OR OR AND 2nd theme OR OR OR AND 3rd theme OR OR OR AND 4th theme? OR OR OR
  • 14. Mind map your question? CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY synonym synonym synonym synonym 1st 2nd theme theme synonym synonym Research question synonym synonym 3rd 4th theme theme synonym synonym synonym synonym
  • 15. Truncation CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY Treatment treat treats treating • Treat* treated • Treat? treater • Treat$ treatment treatments
  • 16. From topic to search CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY Truncation / wildcards? 1 – teenagers OR teens OR adolescents AND 2 – patient education OR patient information AND 3 – blood sugar OR blood glucose OR hypoglycaemia OR hyperglycaemia
  • 17. Task CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY • Go to http://wok.mimas.ac.uk • Open Web of Science • Type a key word, and search by “topic” • How many hits? • Type the keyword with some truncation (use *) • How many hits?
  • 18. From topic to search CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY • Where in the article record do you want the terms/keywords to appear? • Title? • Abstract? • All/any field? • Impact on sensitivity/specificity?
  • 19. Task CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY • Go to http://wok.mimas.ac.uk • Open Web of Science • Type a key word, and search by “topic” • How many hits? • Type a keyword and search by “title” • How many hits?
  • 20. CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY
  • 21. CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY http://www.ncbi.nlm.nih.gov/pubmed/201
  • 22. From topic to search CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY MeSH 1 – teen* OR adolesce* OR "Adolescent"[Mesh] AND 2 – patient education OR patient information OR "Patient Education as Topic"[Mesh] AND 3 – blood sugar OR blood glucose OR hypoglycae* OR hyperglyca* OR "Blood Glucose"[Mesh] OR "Hypoglycemia"[Mesh]
  • 23. From topic to search CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY Inclusion / exclusion criterion? teen* OR adolesce* OR "Adolescent"[Mesh] AND patient education OR patient information OR "Patient Education as Topic"[Mesh] AND blood sugar OR blood glucose OR hypoglycae* OR hyperglyca* OR "Blood Glucose"[Mesh] OR "Hypoglycemia"[Mesh] Year of publication? Humans vs Animals? Type of publication? Language of publication?
  • 24. 1 clinical trial.pt. 24 or/13-23 46 exp Bed Rest/ CAMBRIDGE UNIVERSITY LIBRARY 2 randomized.ab,ti. MEDICAL LIBRARY 47 bed rest.mp. 25 exp Spine/ 3 placebo.ab,ti. 26 discitis.ab,ti. 48 or/39-47 4 dt.fs. 27 exp Spinal Diseases/ 49 24 or 38 5 randomly.ab,ti. 28 (disc adj degeneration).ab,ti. 50 12 and 49 6 trial.ab,ti. 29 (disc adj prolapse).ab,ti. 51 48 and 50 7 groups.ab,ti. 30 (disc adj herniation).ab,ti. 8 or/1-7 31 spinal fusion.sh. 9 Animals/ 32 spinal neoplasms.sh. 10 Humans/ 33 (facet adj joints).ab,ti. 11 9 not (9 and 10) 34 intervertebral disk.sh. 12 8 not 11 35 postlaminectomy.ab,ti. 13 dorsalgia.ab,ti. 36 arachnoiditis.ab,ti. 14 exp Back Pain/ 37 (failed adj back).ab,ti. 15 exp Low Back Pain/ 38 or/25-37 16 backache.ab,ti. 39 exp activities of daily living/ 17 (lumbar adj pain).ab,ti. 40 activities of daily living.tw. 18 coccyx.ab,ti. 41 day to day activ$.ti,ab. 19 coccydynia.ab,ti. 42 daily activit$.ti,ab. 20 exp Sciatica/ 43 ordinary activit$.ti,ab. 21 sciatica.ab,ti. 44 normal activit$.ti,ab. 22 spondylosis.ab,ti. 45 stay$ active.ti,ab. 23 lumbago.ab,ti.
  • 25. 1 clinical trial.pt. 24 or/13-23 46 exp Bed Rest/ CAMBRIDGE UNIVERSITY LIBRARY 2 randomized.ab,ti. MEDICAL LIBRARY 47 bed rest.mp. 25 exp Spine/ 3 placebo.ab,ti. 26 discitis.ab,ti. 48 or/39-47 4 dt.fs. 27 exp Spinal Diseases/ 49 24 or 38 5 randomly.ab,ti. 28 (disc adj degeneration).ab,ti. 50 12 and 49 6 trial.ab,ti. 29 (disc adj prolapse).ab,ti. 51 48 and 50 7 groups.ab,ti. 30 (disc adj herniation).ab,ti. 8 or/1-7 31 spinal fusion.sh. 9 Animals/ 32 spinal neoplasms.sh. 10 Humans/ 33 (facet adj joints).ab,ti. 11 9 not (9 and 10) 34 intervertebral disk.sh. 12 8 not 11 35 postlaminectomy.ab,ti. 13 dorsalgia.ab,ti. 36 arachnoiditis.ab,ti. 14 exp Back Pain/ 37 (failed adj back).ab,ti. 15 exp Low Back Pain/ 38 or/25-37 16 backache.ab,ti. 39 exp activities of daily living/ 17 (lumbar adj pain).ab,ti. 40 activities of daily living.tw. 18 coccyx.ab,ti. 41 day to day activ$.ti,ab. 19 coccydynia.ab,ti. 42 daily activit$.ti,ab. 20 exp Sciatica/ 43 ordinary activit$.ti,ab. 21 sciatica.ab,ti. 44 normal activit$.ti,ab. 22 spondylosis.ab,ti. 45 stay$ active.ti,ab. 23 lumbago.ab,ti.
  • 26. CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY Advice to rest in bed versus advice to stay active for acute low-back pain and sciatica The objective of this review is to determine the effects of advice to rest in bed or stay active for patients with acute low-back pain or sciatica. The following comparisons will be made: • Bed rest versus staying active • Bed rest versus other treatments (besides staying active) • Shorter periods of bed rest versus longer periods of bed rest • Staying active versus other treatments (besides bed rest) • Comparison between different forms of advice to stay active (e.g. avoiding bedrest, staying active) http://mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD007612/pdf_fs.html
  • 27. From topic to search: CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY same strategy, different words Moving from one database to another…..
  • 28. From topic to search: CAMBRIDGE UNIVERSITY LIBRARY same strategy, different words MEDICAL LIBRARY Medline (via OVID) Embase (via OVID) 1 Epidemiologic studies/ 1 Clinical study/ 2 Exp case control studies/ 2 Case control study 3 Exp cohort studies/ 3 Family study/ 4 Case control.tw. 4 Longitudinal study/ 5 (cohort adj (study or studies)).tw. 5 Retrospective study/ 6 Cohort analy$.tw. 6 Prospective study/ 7 (Follow up adj (study or studies)).tw. 7 Randomized controlled trials/ 8 (observational adj (study or studies)).tw. 8 6 not 7 9 Longitudinal.tw. 9 Cohort analysis/ 10 Retrospective.tw. 10 (Cohort adj (study or studies)).mp. 11 Cross sectional.tw. 11 (Case control adj (study or studies)).tw. 12 Cross-sectional studies/ 12 (follow up adj (study or studies)).tw. 13 Or/1-12 13 (observational adj (study or studies)).tw. 14 (epidemiologic$ adj (study or studies)).tw. 15 (cross sectional adj (study or studies)).tw. 16 Or/1-5,8-15 • http://www.sign.ac.uk/methodology/filters.html Observational Study Filters
  • 29. From topic to search: CAMBRIDGE UNIVERSITY LIBRARY same strategy, different words MEDICAL LIBRARY Medline (via OVID) Medline (via Pubmed) 1 Epidemiologic studies/ #1 “Epidemiologic studies”[Mesh] 2 Exp case control studies/ #2 “case control studies”[Mesh] 3 Exp cohort studies/ #3 “cohort studies”[Mesh] 4 Case control.tw. #4 Case control[Text Word] 5 (cohort adj (study or studies)).tw. #5 (cohort stud*))[Text Word] 6 Cohort analy$.tw. #6 Cohort analy*[Text Word] 7 (Follow up adj (study or studies)).tw. #7 (Follow up AND (study or studies))[Text Word] 8 (observational adj (study or studies)).tw. #8 (observational AND (study or studies))[Text 9 Longitudinal.tw. Word] 10 Retrospective.tw. #9 Longitudinal[Text Word] 11 Cross sectional.tw. #10 Retrospective[Text Word] 12 Cross-sectional studies/ #11 Cross sectional[Text Word] 13 Or/1-12 #12 “Cross-sectional studies”[Mesh] #13 #1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11 OR #12 • http://www.sign.ac.uk/methodology/filters.html Observational Study Filters
  • 30. Keywords CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY introducing the research topic reviewing relevant literature • identifying keywords and synonyms and MeSH • structuring your search strategy with boolean logic References • DON’T plagiarise! • Don’t lose marks through sloppy references
  • 31. Sensitivity vs Specificity CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY
  • 32. Sensitivity vs Specificity CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY
  • 33. Sensitivity vs Specificity CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY
  • 34. CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY introducing the research topic reviewing relevant literature Identify relevant sources (and then search them!) • http://www.lib.cam.ac.uk/electronicresources/ databases? • Google? Search by Organisation websites? hand searching? • Which journals are key to your work? snowballing? • WoK or Scopus books? • LibrarySearch or COPAC or GoogleBooks grey literature? • Google: blog search; SIGLE; conference proceedings ongoing trials? • Trials registers
  • 35. CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY introducing the research topic CASP http://www.casp-uk.net reviewing relevant literature Identify relevant sources (and then search them!) “How to read a paper” Trish Greenhalgh References & PDFs WB 18.343 – in the Medical Library or http://tinyurl.com/bmj-trish • Critically appraising Zotero Mendeley • managing EndnoteWeb Endnote • storing Reference Manager RefWorks • using them (cite while you write) Papers • Data extraction Pdf xchange Prisma
  • 36. CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY introducing the research topic reviewing relevant literature Identify relevant sources (and then search them!) References Keeping up to Date • alerts Email alerts • journal TOCs RSS fees • citation tracking
  • 37. CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY introducing the research topic reviewing relevant literature Identify relevant sources (and then search them!) References Keeping up to Date Management of process and results – more info on data management • What is the data you need to record? • Where will you record it? Where will you store it? • How will you record it? • How will you share it? When should all this start?
  • 38. CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY introducing the research topic reviewing relevant literature Identify relevant sources (and then search them!) References Keeping up to Date Management of process and results Writing Up • what did you actually do? • and where did you do it? (750 words?) • Search log/diary • Results matrix • Tidying up your strategy • What did you find, where? • Explicit criterion = reproducable methodology
  • 39. CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY http://www.bmj.com/content/328/7446/991.full.pdf http://jech.bmj.com/content/61/12/1069.full.pdf
  • 40. Books that might help CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY • http://search.lib.cam.ac.uk/?itemid=|cambrdgedb|1258728 http://search.lib.cam.ac.uk/?itemid=|cambrdgedb|317470 http://search.lib.cam.ac.uk/?itemid=|cambrdgedb|4750307 http://search.lib.cam.ac.uk/?itemid=|cambrdgedb|4850812
  • 41. Stopping CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY • Repetition • Change in ratio of “good” : ”bad” articles retrieved • Boundaries/Parameters? • Databases are not infinite: • if your strategy is good enough, and your current awareness strategy is in place, trust it, and stop.
  • 42. CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY
  • 43. Help! CAMBRIDGE UNIVERSITY LIBRARY MEDICAL LIBRARY Isla Kuhn Reader Services Librarian Medical Library Box 111 Addenbrooke’s Hospital email: ilk21@cam.ac.uk phone: (01223) (3)36750 web: http://library.medschl.cam.ac.uk Thank you.

Editor's Notes

  1. What is data? What’s the issue? = fragile – data format, elusive (particularly just when you need it!) = part of research methodology & part of legacy – people might want to build on your work = how much of what you produce will you want/need to keep Where will you record/store it? = multiple copies, multiple places (confidential data permitting) = Key things to consider here are: the names you give files and folders use of tags, or information in file properties whether you need to conform to any conventions in your field How will you share it? = why should you? Reputation Funding Impact Re-use = where? Dspace? Use repositories and data centres Choose open or controlled access Consider embargoes and redactions if necessary