Implementation of a Quantum Perceptron
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2022 Undergraduate Research Symposium: Lucas Huss Quantum Artificial Intelligence (QAI) is an emerging field that could lead to a dramatic decrease in computational power consumption. QAI uses quantum computers which have some key advantages allowing for computational tasks not possible to do with classical computers. The most intuitive way to create QAI is to mimic a neuron, this model is referred to as a quantum perceptron. Current quantum perceptron models require the use of fault-tolerant quantum computers. However, today’s quantum computers are still noisy and prone to errors, which limits the practical implementation of previously proposed quantum perceptron models. In this research we implement a quantum perceptron made for today’s quantum computers, this is done by lowering the error threshold and improving the training procedure. The model is implemented on IBM’s quantum simulator and is applied to a pattern recognition task.
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PDF at - http://www.slideshare.net/deepankarsandhibigraha/quantum-computing-73031375
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This uncontrolled blood pressure also negatively impacts cognitive function and adherence to rehabilitation programs. Additionally, the lesion itself impairs motor function thereby resulting in decreased physical activity and impaired mitochondrial function. Moreover, autonomic dysfunction can lead to an increased risk of stroke, and therefore increased mortality. Mild intermittent hypoxia (MIH), an experimental protocol in which participants experience lower oxygen, in a controlled and repetitive sequence, has been shown to improve blood pressure control in humans.
Our study aims to investigate the impact of MIH on autonomic dysfunction during in-lab provocation and during in-home testing. Likewise, we will also investigate the impact of MIH on mitochondrial and microvascular function and motor function. Our preliminary data shows that MIH may improve autonomic dysfunction which may be explained by improvements in baroreceptor and/or mitochondrial and endothelial function. As evidenced by our preliminary data, MIH is a promising potential protocol for improving health-related quality of life in those with SCI.Utilization of In vivo Longitudinal PET Imaging to Assess Class IIa HDAC Acti...
Utilization of In vivo Longitudinal PET Imaging to Assess Class IIa HDAC Acti...Wayne State University College of Liberal Arts and Sciences
2023 Undergraduate Research Symposium: Mahmoud Teran
The development of memories, including those throughout extinction learning, require neuroplasticity for encoding and retrieval to occur. As environmental factors can affect gene expression, epigenetic changes can play a critical role in the development of memory formation and updating and ultimately manifesting in behavioral changes reflective of the learning.
The purpose of the current project is to show the utility of Positron Emission Tomography (PET), a functional, molecular imaging technique that employs radioactive substances to measure specific markers in the brain. As part of our efforts to understand the neurobiological mechanisms of fear learning and the role of epigenetic changes using PET, images of the brains were collected before and after extinction learning of acquired long-term fear (LTF) memories induced by shock tone pairings made every 30 seconds over 38 min.
PET images were collected by injecting the radiotracer [18F]TFAHA, a substrate for class IIa histone deacetylases (HDACs). The resulting accumulation of the breakdown product of [18F]TFAHA could be considered as a proxy for class IIa HDAC expression changes before and after LTF memory. HDAC activity is directly related to gene expression changes through deacetylation of histone lysine residues. This results in a closed chromatin conformation and prevents the binding of RNA polymerase II and ultimate gene transcription and protein synthesis.
This can then be manifested and seen as behavioral change. Our preliminary analysis of PET images results indicate a significant interaction effect between pre-to-post class IIa HDAC expression-activity, sex, and shock condition. Additional PET image analysis is anticipated to show the extent of HDAC activity in both the sexes following LTF.Developmental Defects in Adolescents as a Result of the Pandemic.pptx
Developmental Defects in Adolescents as a Result of the Pandemic.pptxWayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Christina Kort
There are five developmental factors discussed throughout the review that are applicable to adolescents during the pandemic. This involves the incorporation of nutrition and exercise health, in which a lack of physical activity or appropriate eating habits may be hindering growth.
Learning experiences have been altered to a digital platform and have deeply affected students' motivation and cognitive engagement. Forming strong social connections with friends and members of the community is another way to help ensure that developing brains are progressing. In some cases, the home environment may be negatively impacting the ability to complete work or achieve personal space. Taking some time away or setting boundaries around family may be crucial for growth.
The last aspect necessary for adolescents to sustain positive development consists of a daily structure. Staying active in recreational activities is a good way to ensure structure and can greatly benefit the other factors related to forming new bonds and getting physical exercise.Investigating High Rates of Suicidal Ideation in Individuals Who Stutter
Investigating High Rates of Suicidal Ideation in Individuals Who StutterWayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Mary Tooma
Graduate co-author: Emily Graham LeRose
This research was conducted to investigate the underlying etiological cause(s) and/or psychosocial contributions to suicidal ideation as highly self-reported among individuals with a developmental stutter.
A comprehensive literature review was completed to explore two of the hypothesized components thought to increase risk for suicidal ideation in this population; genetic heritability of suicidal ideation and the presence of co-morbid mental health disorders arising as a result of having a stutter (i.e., depression, anxiety, etc.). Additionally, an empirical review was completed for recommendations to improve overall outcomes in therapy for individuals who stutter.
Results from this investigation of the literature found the most empirical support for a connection between high rates of co-morbid mental health disorders and suicidal ideation in individuals who stutter. Additionally, a therapeutic approach titled "Attachment-Based Family Therapy" has been shown to be highly effective in treating individuals, particularly adolescents, who experience suicidal ideation and depression.Iridium (III) Complexes as Sensors for Cytochrome P450 Enzymes
Iridium (III) Complexes as Sensors for Cytochrome P450 EnzymesWayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Justin Ahrens
Graduate co-author: Maddy Denison
The main goal of this project is to use IrIII complexes to monitor cytochrome P450 (CYP) activity. CYP P450 metabolism determines how quickly drugs are excreted from the body and what kind of dose is required for pharmaceuticals to be effective.
Existing probes for CYPs are non-fluorescent, but when CYPs metabolize them, they are “turned on” and fluoresce. Even though these probes are able to monitor metabolism, once they are metabolized and “turned on” they cannot be reversed or turned off. Therefore, this is no current way to monitor dynamic changes in CYP activity continuously over time.
The Kodanko laboratory is addressing this unmet need by developing IrIII complexes that are reversible sensors of CYP enzymes. A chiral resolution strategy with enantioenriched ligands was used to prepare four analogs of IrIII complexes with different stereochemistry. These complexes were evaluated as emissive sensors in human liver hepatocytes to establish which IrIII complex is the lead compound for sensing CYP in living cells. Results from this multi-disciplinary study will be reported.Mental Health and Incarceration
2022 Undergraduate Research Symposium: Bahea Nasser
My research is overall in the issue of the mass incarceration rate of people with serious mental illness. My research goes into detail about the factors and causes of this problem, re-offending, deinstitutionalization, other important information, and how people with serious mental illness in the criminal justice system receive inadequate treatment.
Accounting Evolution
2022 Undergraduate Research Symposium: Tareq Murshed
Accounting has had major developments and throughout the years it has went from pen and paper to paperless.
Misuse of Analgesics and How They Contribute to the Opioid Epidemic
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2022 Undergraduate Research Symposium: Hanna Alfasih
This research is about the misuse of analgesics and how they have contributed to the opioid epidemic.How Can CRNAs Better Help/Understand Their Patients?
How Can CRNAs Better Help/Understand Their Patients?Wayne State University College of Liberal Arts and Sciences
This document summarizes a presentation on how CRNAs can better help and understand their patients. It discusses several ways for CRNAs to improve patient care and understanding, such as understanding how the healthcare system works to help patients with affordable treatment options, staying updated on new technologies, learning to communicate collaboratively with anesthesiologists, and understanding patients' financial stresses. The presentation also reviews 6 articles on related topics and identifies some limitations in finding relevant sources. It concludes that sharing this information could help medical staff better understand and care for patients to reduce their emotional and physical stress.The Male and Female Gaze in Film Theory
2022 Undergraduate Research Symposium: Ma'ldah Sheikh
The male gaze is a point of view in literary and digital media. It is from the viewing pleasure and perspective of heterosexual men. This form of content is predominantly characterized by the objectification and sexualization of women and other minority groups. The female gaze is meant to oppose the male gaze in cinema, but there are many controversies pertaining to this within the film discourse community.
Many theorists debate that there is no such thing as the female gaze, while others argue that even with the existence of the female gaze, the male gaze can never truly be reversed.
WSU CAPS Resource: Mental Health Screening Utilization
WSU CAPS Resource: Mental Health Screening UtilizationWayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Vivian Truong
Young adults (18-25) have the highest prevalence (29.4%) of any mental illness and the lowest rate of receiving mental health services (38.9%; NIMH). WSU CAPS provides Wayne State students with an online mental health screening opportunity. The numbers of screenings were of interest for this project.
COVID-19 has been shown to negatively impact students’ social and academic engagement, as a result, screening usage during the pandemic was expected to increase. Additionally, the literature on gender and racial/ethnic disparities in mental health service utilization suggest that screening tools may be used less by men and underrepresented minorities. We also expected gender and racial disparities in use, despite the anonymity provided by online screening.
We examined screening use during the pandemic from 3/15/2020 to 6/15/2021 in comparison with pre-pandemic use from 3/15/2018 to 6/15/2019. It is found that the rate of screening is slightly elevated during the pandemic. Secondly, the rate of screening use among different demographic groups, specifically racial/ethnic groups, and gender groups during the fall of 2020 was explored. Of the 897 screenings that were completed, White completed more than 50% of them. Black students were less likely to be screened (12.2% versus 14.8%, p < .01), as were Hispanic students (3.3% versus 5%, p < .001).
Surprisingly, Asian students were more likely to complete the screening (16% versus 10.2%, p < .001). Students who identified as male were highly underrepresented among those who completed the screenings (17.5% versus 40.7% of students).Are Health Awareness Months Dedicated to Urological Diseases Effective at Inc...
Are Health Awareness Months Dedicated to Urological Diseases Effective at Inc...Wayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Shane Tinsley
Introduction: Disease-specific health awareness (HA) campaigns have rapidly developed as an important avenue to improve patient education and ideally outcomes. Our study objective was to understand the impact of urological HA months on engaging public search interests in the United States.
Methods: We utilized Google Trends to examine public health interest in urologic conditions during monthly awareness campaigns over a 17-year period (2004-2021). Relative Search Volume (RSV) during the annual HA campaign months relative to non-health awareness (NHA) campaign months was calculated. Differences between HA-RSV and NHA-RSV months were compared using t-test.
Results: Although small increases in public interest were noted for certain diseases (prostate cancer in November, testicular cancer in April and erectile dysfunction), there was interestingly a comparative decrease in RSV for other diseases (bladder cancer, prostate cancer in September, testicular cancer in November, kidney cancer, benign prostate hyperplasia and male infertility) in their respective HA months; however, none of these differences were statistically significant (p > 0.05).
Conclusion: Our study did not find a significant difference in public interest of any urological diseases during their respective HA campaign months. This highlights the critical need for further research to investigate potential improvements in campaign methodology during dedicated HA months to better achieve their goals of increased public health engagement.Adolescent Suicide to School Psychologists
Adolescent Suicide to School PsychologistsWayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Avery Bacheller
My research abstract explains the importance of adolescent suicide by breaking down statistics, defining the discourse community, citing and explaining sources that help build a good argument for my thesis. All of these combined help me to spread awareness and information regarding adolescent suicide.The Importance of Rural Family Physicians
The Importance of Rural Family PhysiciansWayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Taha Kader
Family physicians are crucial to providing appropriate medical care in rural areas. Family physicians tackle various roles such as maternity and emergency care in these areas. However, there aren't nearly enough family physicians in these areas, and something needs to be done.Quality Matters: A Procedure for Valid and Reliable Hippocampal Subfield Segm...
Quality Matters: A Procedure for Valid and Reliable Hippocampal Subfield Segm...Wayne State University College of Liberal Arts and Sciences
2022 Undergraduate Research Symposium: Samaah Saifullah
Graduate co-author: Kelsey L. Canada
Automated hippocampal subfield segmentation methods have led to exponential growth in the literature. Although automated segmentation is perfectly reliable, deviations from anatomical definitions are common and weaken their validity.
To address the lack of guidance for quality control (QC) of automated segmentation methods, we developed a taxonomy of errors and two-step protocol for 1) identification and 2) manual correction. Raters examined segmentations from a customized atlas to identify errors in six categories with severity ratings; only major severity errors are manually corrected in order to minimize introducing human error.
The QC procedure was developed and cross-validated with an independent sample on two MRI scanners. Raters had excellent agreement in QC decisions between- and within-raters on all regions, manual corrections introduced less than 3% error and were unrelated to participant demographic.
The feasible and reliable QC procedure allows confident interpretation of hippocampal subfield segmentations, and potential applications to other brain regions.More from Wayne State University College of Liberal Arts and Sciences (20)
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