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From Bioinstrumentation to BioMEMS [email_address] ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Early history of bioinstrumentation @ IITB ,[object Object],[object Object],[object Object],[object Object],[object Object]
Subsequent Developments ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
New developments in EE (1)  ,[object Object],[object Object],[object Object]
New developments in EE (2) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
New developments in EE (3) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
New developments in EE (4) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Bio-instrumentation with SBME ,[object Object],[object Object],[object Object]
Bio-instrumentation with SBME (2) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Bio-instrumentation with SBME (3) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Biosensor work with Chemistry ,[object Object],[object Object],[object Object]
Why Conducting Polymers? ,[object Object],[object Object],[object Object],[object Object]
Conducting polymer ENFET Cross-section of  a biosensor Sensor response Substrate Source Drain H +  Enzyme Enzyme catalyzed reaction  H +   /           /  Substrate 0  10  20  30  40  50  60 0.30 0.25 0.20 0.15 0.10 0.05
Sensor materials &   Sensors work in the   ELab  ,[object Object],[object Object]
Sensor materials ,[object Object],[object Object],[object Object],[object Object]
Some   biosensors in   ELab  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Why EOS? ,[object Object],[object Object],[object Object],[object Object],[object Object]
 Sensors (EOS system based) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
What can be exploited in EOS systems for Biosensors? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
EOS Capacitor ,[object Object],[object Object],[object Object],Electrolyte Silicon Oxide Example: EOS capacitor ~
Capacitive affinity biosensors ,[object Object],[object Object],[object Object],[object Object],Silicon Antigen Antibody
ISFET ,[object Object],[object Object],[object Object],[object Object],P-type silicon N + N + + + + + + - - - - - Source Drain Encapsulation Metal Contacts electrons + [SiO 2 +Si 3 N 4 ] + Analyte + + + + + + A H + + + RE
bioMEMS made in the   Elab: Microelectroporator  ,[object Object],[object Object],[object Object]
bioMEMS made in the   ELab(2): Microelectroporator   SEM & optical micrographs of micro pore
bioMEMS made in the   ELab(3): Microelectroporator   Electroporator Cell Pulse output due to a ~15   m particle
bioMEMS made in the   ELab(5):  CE ,[object Object],[object Object],[object Object],Source Sink Dispersive  drift channel Detector system
bioMEMS made in the   ELab(5):  CE
bioMEMS made in the   ELab(6):  CE
A whiff off what we plan to do ,[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusions ,[object Object],[object Object],[object Object],[object Object]
The Team  (or shall we say morphing teams!) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Bio mems lal-1

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  • 13. Conducting polymer ENFET Cross-section of a biosensor Sensor response Substrate Source Drain H +  Enzyme Enzyme catalyzed reaction  H +  /     /  Substrate 0 10 20 30 40 50 60 0.30 0.25 0.20 0.15 0.10 0.05
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  • 24. bioMEMS made in the  ELab(2): Microelectroporator SEM & optical micrographs of micro pore
  • 25. bioMEMS made in the  ELab(3): Microelectroporator Electroporator Cell Pulse output due to a ~15  m particle
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  • 27. bioMEMS made in the  ELab(5):  CE
  • 28. bioMEMS made in the  ELab(6):  CE
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