This document provides an overview of a project studying a magnetoimpedance biosensor. The objectives are to detect different types of biomolecular tissues, proteins, and damaged cells using magnetic particles and detecting changes in impedance. Motivation includes low power consumption, fast response time, and high stability. Literature reviewed includes detection of gastric cancer cells using magnetoimpedance. Future work could develop applications to detect tissues not currently detectable. The magnetoimpedance biosensor has potential benefits for society by enabling earlier detection of diseases like cancer to reduce mortality rates.

1. By
Surya Teja Swamy
Anoop Puli
Under the Guidance
Syed Shameem
KL Deemed to be a UNIVERSITY
DEPARTMENT OF ECE
StudyofMagnetoimpedance
Biosensor

2. • Introduction
• Objectives of the Project(base paper)
• Motivation for the Project
• Literature Review(base paper and related
papers)
• Inference from the paper
• Problem Identified
• Methods/Methodology
• Advantages & Limitations
• Discussion on Results of the base paper
• Contribution to the society
• Future enhancement
• Plan for Review 2
• References
OVERVIEW OF THE
PRESENTATION

3. 3
INTRODUCTION
Brief about Biosensors

4. Magnetoimpedance Biosensor
Magnetic particles are commonly composed of magnetic elements, such
as iron, nickel, cobalt and their oxides.
Superparamagnetic particles can be magnetized only if subjected to an
external magnetic field, so no residual magnetization retains in the
absence of magnetic field.
They are also easily functionalized with different biochemical substances
that can be used to capture deoxyribonucleic acid, protein, enzymes and
cells

5. Cont…
• Physicochemical stability of the super para magnetic particles enables the
detection and magnetic manipulation without affecting the biological
interactions
• Living systems can produce bio magnetic fields because they are electrically
excitable. Magnetic sensors with sufficiently high sensitivity are able to
detect the bio magnetic fields produced by the biologic tissues or organs, thus
providing a non-invasive mean to detect the activity of the living systems.

6. OBJECTIVES OF THE PROJECT WORK
To detect different types of Bio Molecular Tissues,
Proteins, Damaged Cells due to effect of foreign bodies
in the living organisms.
To reduce the death rate by detecting Malignant
disease causing tissues in advance.
To improve the bio – medical applications by increasing
the rate of detection.

7. MOTIVATION FOR THE PROJECT
•Low Power Consumption
•The GMI Sensor will Consume less power so heat dissipation is less.
•Fast Response
•Due to Faster Response we can detect the disordered cells with in less
time.
•High Stability
•The reason of higher stability the Magnetoimpedance sensor can be work
for high impedance values also.

8. LITERATURE REVIEW
Tao Wang, Yong Zhou, Chong Lei, Jun Luo, Shaorong Xie and Huayan Pu,
Magnetic impedance biosensor, BIOS9253
Inference from the paper:
The magnetoimpedance effect in soft ferromagnetic wires, ribbons and thin films
for biosensing applications
Problem Identified:
Living systems can produce biomagnetic fields because they are electrically
excitable. Magnetic sensors with sufficiently high sensitivity are able to detect the
biomagnetic fields produced by the biologic tissues or organs.
Methods/Methodology:
Thus providing a non-invasive mean to detect the activity of the living systems. i.e,
Biosensor for biomagnetic detections
Advantages & Limitations:
High Sensitivity, Fast Response, High Stability, Low Power Consumption.

9. DISCUSSION ON RESULTS

10. (a) GMI response
of six different
samples at a
frequency of
10MHz
(b) Standard
deviation analysis
of 10 repeated test
results of six
different samples
DetectionofGastricCancerCells

11. CONTRIBUTION TO THE SOCIETY
FUTURE ENHANCEMENT
We had Till now studied the different applications of Magnetoimpedance
Sensor (GMI), how it varies depends on frequency of the magnetic waves
that produced from living organisms. So we need to decided to generate
a new application which can detect a particular tissues which even can’t
detected yet, so that it can be helpful to the society
All the Applications what we had studied till now, from those applications
the Magnetoimpedance Sensor (GMI) is useful to detect different tissues,
fluids, damaged cells … which can be detected by the help of the
magnetic field generated by living organisms. So this project is very
useful to the society where as it detecting some type of Cancer Cells
likewise it can reduce Cancer Deaths

12. REFERENCES
12
An integrated and sensitive detection platform for magneto-
resistive biosensors B.M. de Boer, J.A.H.M. Kahlman, T.P.G.H.
Jansen, H. Duric, J. Veen
Tunneling magnetoresistance sensors for high resolutive particle
detection C. Albon, A. Weddemann, A. Auge, K. Rott, and A. Hütten
Research Progress of Giant Magneto-Impedance (GMI) Sensors
Zhang Zhenchuan, Duan Xiusheng, Li Shengjun
A highly sensitive magnetic biosensor for detection and
quantification of anticancer drugs tagged to superparamagnetic
nanoparticles J. Devkota, J. Wingo, T. T. T. Mai, X. P. Nguyen, N. T.
Huong, P. Mukherjee, H. Srikanth and M. H. Phan
The Magnetic Differentiation Technique for GMI Sensor Jean-
Paul Yonnet and Aktham Asfour
Double-pinned magnetic tunnel junction sensors with spin-valve-
like sensing layers Z. H. Yuan, L. Huang, J. F. Feng, Z. C. Wen, D.
L. Li, X. F. Han, Takafumi Nakano, T. Yu and Hiroshi Naganuma
On-Chip Magnetic Platform for Single-Particle Manipulation
with Integrated Electrical Feedback Marco Monticelli , * Andrea
Torti , * Edoardo Albisetti