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Experimental Formulation:
Stability Testing of Aerosols
GASKET COMPATIBILITY AND WEIGHT LOSS STUDY
By: Valerie Stephens
Chemical Composition: Aerosol 101
• Aerosol is homogeneous blend of propellant and formula
• Formula types:
• Solvent
• Water
• Petroleum Distillate
• 96% Formula
• 4 % Propellant, CO2
• 134A, 152A, Hydrocarbons
Packaging Components
• Valve, dip tube, marble (heterogenous), BOV, actuator
Supplier Elastomer Options
Table 1: Materials by Supplier
Summit Precision
GASKET DIP TUBE GASKET DIP TUBE
36101.042 Buna 38301
Series
05-5110-51 BUNA B175 09-2010 PE
36202.042 Neoprene 05-5110-20 BUNA KA-6712 09-2050
MDPE
36155.042 Butyl 05-5130-19 NEOPRENE N-
200
09-35XX
PP
36251.042 Viton 05-5150-00 BUTYL U133
05-5160-00 VITON V-500
05-5110-27 B218
Gasket Selection
Table 3: Gasket Swell and Durometer Results
Material Type
Temperature Temperature
Room Temp
Swell %
120°F
Swell %
Trail 1 Trial 2 Trial 1 Trial 2
(1) BUNA B175 77 75 2.67 78 74 2.04
(2) BUNA KA-6712 75 69 4.88 75 66 3.94
(3) N-200 80 75 2.04 81 75 2.84
(4) BUTYL U133 77 68 23.11 78 62 23.98
(5) VITON V-500 79 63 7.99 80 66 7.69
(6) B218 80 75 4.72 80 78 3.77
F
a
c
t
o
r
1
Testing the Data
2 Factor ANOVA
Any outcome = overall mean + effect of gasket material + effect due to temperature + random noise
Gasket Material Temperature
SPSS OUTPUT
Weight Loss Correlation
Positive Correlation
High X values & High Y Values
R= 0.89 for BUNA B175 Gasket
This is a good Model for
selecting a gasket
Conclusions
Durometer Hardness is not a good measure of chemical compatibility with
gasket material
Maybe with more data points, only used one type at 2 temperatures and 2
replicated of each
We looked at the weight loss over time to see correlation with gaskets selected
Good correlation and R value

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Aerosol Stability and Durometer Hardness Evaluation

  • 1. Experimental Formulation: Stability Testing of Aerosols GASKET COMPATIBILITY AND WEIGHT LOSS STUDY By: Valerie Stephens
  • 2. Chemical Composition: Aerosol 101 • Aerosol is homogeneous blend of propellant and formula • Formula types: • Solvent • Water • Petroleum Distillate • 96% Formula • 4 % Propellant, CO2 • 134A, 152A, Hydrocarbons Packaging Components • Valve, dip tube, marble (heterogenous), BOV, actuator
  • 3. Supplier Elastomer Options Table 1: Materials by Supplier Summit Precision GASKET DIP TUBE GASKET DIP TUBE 36101.042 Buna 38301 Series 05-5110-51 BUNA B175 09-2010 PE 36202.042 Neoprene 05-5110-20 BUNA KA-6712 09-2050 MDPE 36155.042 Butyl 05-5130-19 NEOPRENE N- 200 09-35XX PP 36251.042 Viton 05-5150-00 BUTYL U133 05-5160-00 VITON V-500 05-5110-27 B218
  • 4. Gasket Selection Table 3: Gasket Swell and Durometer Results Material Type Temperature Temperature Room Temp Swell % 120°F Swell % Trail 1 Trial 2 Trial 1 Trial 2 (1) BUNA B175 77 75 2.67 78 74 2.04 (2) BUNA KA-6712 75 69 4.88 75 66 3.94 (3) N-200 80 75 2.04 81 75 2.84 (4) BUTYL U133 77 68 23.11 78 62 23.98 (5) VITON V-500 79 63 7.99 80 66 7.69 (6) B218 80 75 4.72 80 78 3.77 F a c t o r 1
  • 5. Testing the Data 2 Factor ANOVA Any outcome = overall mean + effect of gasket material + effect due to temperature + random noise Gasket Material Temperature
  • 7. Weight Loss Correlation Positive Correlation High X values & High Y Values R= 0.89 for BUNA B175 Gasket This is a good Model for selecting a gasket
  • 8. Conclusions Durometer Hardness is not a good measure of chemical compatibility with gasket material Maybe with more data points, only used one type at 2 temperatures and 2 replicated of each We looked at the weight loss over time to see correlation with gaskets selected Good correlation and R value