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1. Iron Oxide
Pigments
Pharmaceutical, Food, Cosmetics
Presentation by
Primary Information Services
www.primaryinfo.com
mailto:primaryinfo@gmail.com

2. Introduction
• Iron oxides occur as yellow, red, black, or brown
powder. The color depends on the particle size
and shape, and crystal structure.
• Accepted for use as a food additive in Europe.
Included in nonparental medicines licensed in
many countries including Japan, UK, and USA
• Iron oxides are widely used in cosmetics, foods,
and oral and topical pharmaceutical applications.
They are generally regarded as nontoxic and
nonirritant excipients. The use of iron oxide
colorants is limited in some countries, such as the
USA, to a maximum ingestion of 5 mg of
elemental iron per day.
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3. Iron oxides [1332-37-2] (a) Iron oxide
black [1317-61-9] (b) Iron oxide red
[1309-37-1] (c) Iron oxide yellow
[51274-00-1] (monohydrate); [20344-
49-4] (hydrate)
Chemical Name and CAS
Registry Number
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4. Applications in
Pharmaceutical
Formulation or
Technology
• Iron oxides are widely used in
cosmetics, foods, and
pharmaceutical applications as
colorants and UV absorbers.
• As inorganic colorants they are
becoming of increasing importance
as a result of the limitations
affecting some synthetic organic
dyestuffs.
• However, iron oxides also have
restrictions in some countries on
the quantities that may be
consumed, and technically their use
is restricted because of their limited
color range and their abrasiveness.
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5. Three main manufacturing processes are
currently applied for iron oxide pigments:
(a) Solid-state reactions (red, black and
brown): calcination of black or yellow
iron oxides to red iron oxide; thermal
decomposition of ferrous sulfate.
(b) Precipitation process (red, orange,
yellow and black): treatment of ferrous
sulfate solutions with alkali and oxidation.
The Penniman–Zoph process uses
ferrous sulfate, alkali, iron powder and air
or oxygen.
(c) Laux process or aniline process (red,
yellow, and black): reduction of
nitrobenzene to aniline with iron
Method of Manufacture

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7. pharmaceutical
grade
iron
oxide
pigments
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Presentation Title 7

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Iron oxide pharmaceutical excipients are
mainly used for various types of pills, coat
coloring agent. Additional Information. Item
Code, KoelinPH-919
Iron Oxide Yellow
Powder, Drum
₹ 2,000/ Kg

9. Manufacturer
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Iron oxides are widely used as industrial food
pigments to color sweets, olives or cheese rind (EFSA,
2015). The European Union classifies iron oxides as
food additives with the number E172 (EU, 2008).

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Combination of Silica & Iron Oxide
- Red Colour