Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression. When overexpressed, promotes cells to enter into S phase and proliferation. To purchase this antibody, use the following link: http://www.stjohnslabs.com/nanog-antibody-p-42918?filter_name=STJ31850

1. HOW DID OUR
ANTIBODY PERFORM?
CUSTOMER REVIEW: NANOG Monoclonal Antibody (STJ31850)

2. WHAT WAS THE PROTOCOL?
Primary antibody: Product Catalog No: STJ31850.
NANOG monoclonal antibody.
Provider: St John's Laboratory
Method for validation: Immunohistochemistry
Dilution ratio: 1:500

3. WHAT DID THE CUSTOMER THINK?
Testing results were provided by Warangkana
Lohcharenkal from Karolinska Institutet. They stated that
“The product did give conclusive results.”

4. “WE INVITE YOU TO TEST OUR PRODUCTS”
Our aim is to not only connect our customers
with the best product, but to also give them
the opportunity to test the product’s
performance risk free.

5. Contact Us: info@stjohnslabs.com
1. Choose 5 Trial Size Samples from our free sample list
2. Complete the free sample application: http://www.stjohnslabs.com/free-sample
3. Receive your antibody
4. Submit your review
5. Receive your 30% off your next order
Get Your Free Samples in 5 Easy Steps

6. Follow Us for Weekly Independent
Validation Reviews
@StJohnsLabsSt John's Laboratory Ltd
St John's Laboratory Ltd St John's Laboratory Ltd
http://www.slideshare.net/stjohnslabs