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UNIVERSITY OF ENGINEERING AND
MANAGEMENT,JAIPUR,RAJASTHAN
SOUDIP SINHA ROY
3RD YEAR
DNA NANOBIOTECHNOLOGY
CONCEPTS AND APPLICATIONS
ABSTRACT:
DNA nanobiotechnology uses DNA structures and properties for constructing
nanostructured material and utilizes those nanostructured materials in biological,
engineering, and medical applications.
BACKGROUND AND INTRODUCTION:
• DISCOVERY OF THE STRUCTURE OF THE DNA IN 1953 BY WATSON AND CRICK
NATURE HAS BEEN AN INSPIRATION
• DNA HAVING UNIQUE PROPERTIES, SUCH AS A NANOSCALE STRUCTURAL GEOMETRY, INFORMATION
ENCODING, SELF-REPLICATING, AND SELF-ASSEMBLY, HAVE DEMONSTRATED IT AS AN EXCELLENT
FUNDAMENTAL BUILDING BLOCK MATERIAL FOR MOLECULAR NANOTECHNOLOGY
• DNA CAN BE USED AS A BOTTOM-UP CONSTRUCTION MEDIUM, A BUILDING BLOCK FOR SELF-ASSEMBLY
AND AS A NANOSTRUCTURE TO CONSTRUCT PERIODIC ASSEMBLIES AND COMPLEX NANOSTRUCTURES
• USING THE DNA AS A BOTTOM-UP CONSTRUCTION MOLECULE TO BUILD 3D ARRAYS. EXPLORING AND
IMPROVING ITS PROPERTIES TO PRODUCE AT A HIGHER DIMENSIONS
THEORETICAL BACKGROUND:
STRUCTURE AND PROPERTIES OF DNA (DEOXYRIBONUCLEIC
ACID)
CLASSIFICATIONS OF DNA
A DNA B DNA Z DNA
DETAILS ABOUT DNA GENETIC CODONS
THE NAMES OF DNA CODONS
A- ADENINE = 00
T- THYMINE = 01
G- GUANINE = 10
C- CYTOSINE = 11
An example– ( ATCCGT
=000111111001)
• The codes are very useful for the
calculation at the time of
chromosomal reactions as well as
D N A D E C O D E R W H E E L
A V E R Y R E L A T I O N W I T H T E C H N O L O G Y
MORE PRECISE
FUTURE DIRECTIONS :
DNA computation
Drug Discovery Through (DTS)
Designing electronic circuit structures using DNA self-assembly
techniques
DNA motors to perform DNA like tasks and enhancement to nano
robots
Development of in vivo nano-sensors, etc.
Grand challenge :
To find an error correction method to solve problems in self-
assembly methods
Technical challenges :
to explore its electromagnetic, electrochemical and catalytic
properties
to produce high order object, arrays and lattices in 3D
to build efficiently self-assembled steady complex structures from
nano scale to macro-scale structures, etc.

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DNA NANOBIOTECHNOLOGY

  • 1. UNIVERSITY OF ENGINEERING AND MANAGEMENT,JAIPUR,RAJASTHAN SOUDIP SINHA ROY 3RD YEAR
  • 3. ABSTRACT: DNA nanobiotechnology uses DNA structures and properties for constructing nanostructured material and utilizes those nanostructured materials in biological, engineering, and medical applications. BACKGROUND AND INTRODUCTION: • DISCOVERY OF THE STRUCTURE OF THE DNA IN 1953 BY WATSON AND CRICK NATURE HAS BEEN AN INSPIRATION • DNA HAVING UNIQUE PROPERTIES, SUCH AS A NANOSCALE STRUCTURAL GEOMETRY, INFORMATION ENCODING, SELF-REPLICATING, AND SELF-ASSEMBLY, HAVE DEMONSTRATED IT AS AN EXCELLENT FUNDAMENTAL BUILDING BLOCK MATERIAL FOR MOLECULAR NANOTECHNOLOGY • DNA CAN BE USED AS A BOTTOM-UP CONSTRUCTION MEDIUM, A BUILDING BLOCK FOR SELF-ASSEMBLY AND AS A NANOSTRUCTURE TO CONSTRUCT PERIODIC ASSEMBLIES AND COMPLEX NANOSTRUCTURES • USING THE DNA AS A BOTTOM-UP CONSTRUCTION MOLECULE TO BUILD 3D ARRAYS. EXPLORING AND IMPROVING ITS PROPERTIES TO PRODUCE AT A HIGHER DIMENSIONS
  • 4. THEORETICAL BACKGROUND: STRUCTURE AND PROPERTIES OF DNA (DEOXYRIBONUCLEIC ACID)
  • 5. CLASSIFICATIONS OF DNA A DNA B DNA Z DNA
  • 6. DETAILS ABOUT DNA GENETIC CODONS THE NAMES OF DNA CODONS A- ADENINE = 00 T- THYMINE = 01 G- GUANINE = 10 C- CYTOSINE = 11 An example– ( ATCCGT =000111111001) • The codes are very useful for the calculation at the time of chromosomal reactions as well as
  • 7. D N A D E C O D E R W H E E L A V E R Y R E L A T I O N W I T H T E C H N O L O G Y MORE PRECISE
  • 8. FUTURE DIRECTIONS : DNA computation Drug Discovery Through (DTS) Designing electronic circuit structures using DNA self-assembly techniques DNA motors to perform DNA like tasks and enhancement to nano robots Development of in vivo nano-sensors, etc. Grand challenge : To find an error correction method to solve problems in self- assembly methods Technical challenges : to explore its electromagnetic, electrochemical and catalytic properties to produce high order object, arrays and lattices in 3D to build efficiently self-assembled steady complex structures from nano scale to macro-scale structures, etc.