The document summarizes the work of the World Cancer Research Fund International (WCRF) and American Institute for Cancer Research (AICR) in producing reports on cancer prevention through diet, nutrition, and physical activity. It discusses how the WCRF/AICR conduct systematic reviews of scientific evidence to develop recommendations, and continuously update their findings. Their expert reports conclude that lifestyle factors like smoking, diet, nutrition, weight management, and physical activity have significant impacts on cancer risk, and that many cancers can be prevented through appropriate changes to these behaviors.
What is the current evidence between alcohol and cancer?
Presentation given by Giota Mitrou PhD MSc, Head of Research Funding and Science Activities, World Cancer Research Fund International (WCRF International).
Presentation from the World Cancer Congress, 3-6 December 2014, Melbourne, Australia: Reducing the global cancer burden through policy action on diet, physical inactivity and alcohol
Professor Martin Wiseman’s presentation, The Continuous Update Project: Introduction to the Project, at the African Organisation for Research & Training in Cancer (AORTIC) conference, 18-22 November 2015, Marrakech, Morocco.
Operationalising World Cancer Research Fund/American Institute for Cancer Research Cancer Prevention Recommendations Using an Index Score
ISBNPA 3-6 June 2015
Giota Mitrou PhD MSc
Head of Research Funding & Science External Relations
World Cancer Research Fund International
WCRF International Continuous Update Project (CUP). Presentation given by Giota Mitrou PhD MSc, Head of Research Funding and Science Activities, World Cancer Research Fund International (WCRF International).
Epidemiological evidence linking food, nutrition, physical activity and prostate cancer risk: results from the Continuous Update Project
By Michael Leitzmann, Dept. of Epidemiology and Preventive Medicine, University of Regensburg, Continuous Update Project Panel member
World Cancer Congress, Saturday 6 December 2014
Beryl Pilkington, RN, PhD, School of Nursing, Faculty of Health, York University in Toronto, presented at AMREF's Coffeehouse Speaker Series on global development on the intersection of health and development with specific focus on the community level in the Dadaab refugee camps. The coffeehouse speaker series looks at international development and global health, specifically focusing on Africa.
What is the current evidence between alcohol and cancer?
Presentation given by Giota Mitrou PhD MSc, Head of Research Funding and Science Activities, World Cancer Research Fund International (WCRF International).
Presentation from the World Cancer Congress, 3-6 December 2014, Melbourne, Australia: Reducing the global cancer burden through policy action on diet, physical inactivity and alcohol
Professor Martin Wiseman’s presentation, The Continuous Update Project: Introduction to the Project, at the African Organisation for Research & Training in Cancer (AORTIC) conference, 18-22 November 2015, Marrakech, Morocco.
Operationalising World Cancer Research Fund/American Institute for Cancer Research Cancer Prevention Recommendations Using an Index Score
ISBNPA 3-6 June 2015
Giota Mitrou PhD MSc
Head of Research Funding & Science External Relations
World Cancer Research Fund International
WCRF International Continuous Update Project (CUP). Presentation given by Giota Mitrou PhD MSc, Head of Research Funding and Science Activities, World Cancer Research Fund International (WCRF International).
Epidemiological evidence linking food, nutrition, physical activity and prostate cancer risk: results from the Continuous Update Project
By Michael Leitzmann, Dept. of Epidemiology and Preventive Medicine, University of Regensburg, Continuous Update Project Panel member
World Cancer Congress, Saturday 6 December 2014
Beryl Pilkington, RN, PhD, School of Nursing, Faculty of Health, York University in Toronto, presented at AMREF's Coffeehouse Speaker Series on global development on the intersection of health and development with specific focus on the community level in the Dadaab refugee camps. The coffeehouse speaker series looks at international development and global health, specifically focusing on Africa.
Continuous Update Project: Database update and systematic literature review. Presentation given by Teresa Norat, Principal Investigator Continuous Update Project, Imperial College London.
Yvonne Doyle - High Impact Health Interventions Age UK
Yvonne Doyle, Director of Public Health, Public Health England - presentation from Age UK's For Later Life conference, 25th April 2013.
For more information, view: www.ageuk.org.uk/forlaterlife
Professor Michael Leitzmann presentation on The Continuous Update Project: Recent Findings on Diet, Nutrition, Physical Activity and Cancer at FENS European Nutrition Conference, 20-23 October 2015 Berlin (Germany).
Slides from Alan Jackson's presentation on the Cancer and Nutrition NIHR infrastructure collaboration at Obesity, Physical Activity & Cancer: Life course influences and mechanisms
Skilled Delivery Utilizations & Its Determinants in Four Regions of EthiopiaJSI
The objective was to describe improvements in community awareness of MNH, assess trends and factors contributing to skilled delivery utilization in learning sites, and identify lessons and provide recommendations for MNH program scale up and recommendations.
The conclusion was that a comprehensive approach to MNH and skilled delivery is essential to success. Strong community promotion and partnership is essential to improved service utilization. Respectful and women-friendly services are vital. Post-training mentoring and supportive supervision are indispensable and should be ongoing. Areas needing improvement are: access to transportation, referral systems. supply chain management and essential life-saving commodities, water and electricity in HCs, and improved facility infrastructure as utilization increases
Professor Alan Jackson’s presentation, The Continuous Update Project: Recent Findings on Diet, Nutrition, Physical Activity and Cancer, at the African Organisation for Research & Training in Cancer (AORTIC) conference, 18-22 November 2015, Marrakech, Morocco.
Addressing severe-acute malnutrition in Rajasthan using community-based strat...POSHAN
This presentation was made by Dr. Deepti Gulati (GAIN) in the session on ‘Implementation research on delivery of preventive and curative interventions during early childhood’ at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016, New Delhi.
For more information about the conference visit our website: www.poshan.ifpri.info
Poster presentation outlining results of the University of Gloucestershire's Active Fans project - investigating sports fans' preferences for health improvement programmes
Analysing Research on Cancer Prevention and Survival: Recommendationsnzhempfoods
World Cancer Research Fund (WCRF) and American Institute for Cancer Research (AICR) champions the latest and most authoritative scientific research from around the world on cancer prevention and survival through diet, nutrition and physical activity to help people make informed lifestyle choices to reduce their cancer risk.
Dr Kate Allen: Obesity, Physical Activity and Cancer: Implications for Policy Irish Cancer Society
Dr Kate Allen, Executive Director (Science and Public Affairs) of World Cancer Research Fund International, UK, spoke about the relationship of obesity and physical Activity on cancer, and consequential implications for policy.
Continuous Update Project: Database update and systematic literature review. Presentation given by Teresa Norat, Principal Investigator Continuous Update Project, Imperial College London.
Yvonne Doyle - High Impact Health Interventions Age UK
Yvonne Doyle, Director of Public Health, Public Health England - presentation from Age UK's For Later Life conference, 25th April 2013.
For more information, view: www.ageuk.org.uk/forlaterlife
Professor Michael Leitzmann presentation on The Continuous Update Project: Recent Findings on Diet, Nutrition, Physical Activity and Cancer at FENS European Nutrition Conference, 20-23 October 2015 Berlin (Germany).
Slides from Alan Jackson's presentation on the Cancer and Nutrition NIHR infrastructure collaboration at Obesity, Physical Activity & Cancer: Life course influences and mechanisms
Skilled Delivery Utilizations & Its Determinants in Four Regions of EthiopiaJSI
The objective was to describe improvements in community awareness of MNH, assess trends and factors contributing to skilled delivery utilization in learning sites, and identify lessons and provide recommendations for MNH program scale up and recommendations.
The conclusion was that a comprehensive approach to MNH and skilled delivery is essential to success. Strong community promotion and partnership is essential to improved service utilization. Respectful and women-friendly services are vital. Post-training mentoring and supportive supervision are indispensable and should be ongoing. Areas needing improvement are: access to transportation, referral systems. supply chain management and essential life-saving commodities, water and electricity in HCs, and improved facility infrastructure as utilization increases
Professor Alan Jackson’s presentation, The Continuous Update Project: Recent Findings on Diet, Nutrition, Physical Activity and Cancer, at the African Organisation for Research & Training in Cancer (AORTIC) conference, 18-22 November 2015, Marrakech, Morocco.
Addressing severe-acute malnutrition in Rajasthan using community-based strat...POSHAN
This presentation was made by Dr. Deepti Gulati (GAIN) in the session on ‘Implementation research on delivery of preventive and curative interventions during early childhood’ at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016, New Delhi.
For more information about the conference visit our website: www.poshan.ifpri.info
Poster presentation outlining results of the University of Gloucestershire's Active Fans project - investigating sports fans' preferences for health improvement programmes
Analysing Research on Cancer Prevention and Survival: Recommendationsnzhempfoods
World Cancer Research Fund (WCRF) and American Institute for Cancer Research (AICR) champions the latest and most authoritative scientific research from around the world on cancer prevention and survival through diet, nutrition and physical activity to help people make informed lifestyle choices to reduce their cancer risk.
Dr Kate Allen: Obesity, Physical Activity and Cancer: Implications for Policy Irish Cancer Society
Dr Kate Allen, Executive Director (Science and Public Affairs) of World Cancer Research Fund International, UK, spoke about the relationship of obesity and physical Activity on cancer, and consequential implications for policy.
Professor Martin Wiseman presentation on The Continuous Update Project: Introduction to the Project at FENS European Nutrition Conference, 20-23 October 2015 Berlin (Germany).
Professor Martin Wiseman presented on 'The Continuous Update Project - Breast cancer survivors and prostate cancer' on behalf of WCRF International at the SCPN conference 04/02/2015.
Taking place under the tagline ‘We can. I can.’, World Cancer Day 2016-2018 will explore how everyone – as a collective or as individuals – can do their part to reduce the global burden of cancer.
Just as cancer affects everyone in different ways, all people have the power to take various actions to reduce the impact that cancer has on individuals, families and communities.
World Cancer Day is a chance to reflect on what you can do, make a pledge and take action. Whatever you choose to do ‘We can. I can.’ make a difference to the fight against cancer.
WCD2016 website http://www.worldcancerday.org/ materials http://www.worldcancerday.org/materials and ways to help http://www.worldcancerday.org/get-involved
A methods document explaining how the NOURISHING database is kept up-to-date with implemented government policies on promoting healthy diets and reducing obesity and non-communicable diseases.
Slides from Alan Jackson's presentation on Policy for Enabling Achievement of Height at Obesity, Physical Activity & Cancer: Life course influences and mechanisms
To support governments as they develop national food and nutrition plans and targets, we have produced a new policy brief in collaboration with NCD Alliance.
Senior Policy & Public Affairs Manager, Bryony Sinclair's presentation, Curbing global sugar consumption, at the The Sugar Reduction Summit: Sugar, Sweetness & Obesity, 7 December 2015, London, England.
Bryony Sinclair discussed a systems approach to policymaking for obesity prevention at American Public Health Association's Annual Meeting, 31 Oct - 4 Nov 2015, Chicago, USA.
Professor Martin Wiseman presentation on The Continuous Update Project: Novel approach to reviewing mechanistic evidence on diet, nutrition, physical activity and cancer at FENS European Nutrition Conference, 20-23 October 2015 Berlin (Germany).
A coherent approach: effective policy actions for fruits and vegetables throughout the NOURISHING framework.
Bryony Sinclair
Policy and Public Affairs Manager
World Cancer Research Fund International
In this brief, we provide a guide to available policies that can assist countries in reducing the amount of sugar consumed at a population level to meet the World Health Organization’s sugar guideline.
We illustrate the available policies, provide examples that have worked and include input from those involved in the development and implementation of these policies.
Introduction to the WCRF International Continuous Update Project
By Dr Rachel Thompson, Head of Research Interpretation/ Head CUP Secretariat
6 December 2014, UICC World Cancer Congress, Melbourne
Ethnic differences, obesity and cancer,
stages of the obesity epidemic and cancer prevention
Professor TH Lam, JP, BBS
MD, FFPH, FFOM, Hon FHKCCM, FHKAM, FRCP
Sir Robert Kotewall Professor in Public Health, School of Public Health, The University of Hong Kong
UICC World Cancer Congress Melbourne, Australia 3-6 December 2014
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Ocular injury ppt Upendra pal optometrist upums saifai etawah
Wiseman Martin - 20th International Nutrition Congress 2013
1. Evidence-based recommendations for prevention
of cancer and other chronic diseases
The 2007 and 2009 WCRF/AICR Reports
Martin Wiseman
World Cancer Research Fund International
University of Southampton, UK
www.wcrf.org/ICN2013
IUNS, Granada, 2013
2. Who we are
AICR
WCRF UK
WCRF Netherlands
WCRF Hong Kong
WCRF International
What we do
Fund research on the relationship of
nutrition, physical activity and body
weight to cancer risk
Interpret the accumulated scientific
literature to derive
Recommendations for Cancer
Prevention
Educate people through our national
Health Information programmes
Advocate effective policies to help
people and populations to reduce
their chances of developing cancer
3.
4. Data from Parkin et al, Pisani et al, Globocan 2008, IARC
*Estimated new cases for 2030 from predictions in 2002
10. WCRF/AICR EXPERT REPORT
1.
2.
3.
4.
5.
The most authoritative
New method
Systematic reviews
Review of evidence separate from
judgement
Panel of international experts
Predetermined criteria for judgements
Epidemiology
Mechanisms
6. Flexibility
7. Continuous update of evidence
11. NUTRITION AND CANCERS
OBESITY
BREAST (PM), COLORECTUM, ENDOMETRIUM, OESOPHAGUS,
PANCREAS, GALLBLADDER, KIDNEY
PHYSICAL ACTIVITY
COLON, BREAST, OBESITY
MEAT – RED AND PROCESSED
COLORECTAL
PLANT FOODS
MPL, OESOPHAGUS, STOMACH,) COLORECTAL, LUNG, OBESITY
ALCOHOL
MPL, COLORECTUM, LIVER, BREAST
SALT
STOMACH
BREASTFEEDING
BREAST, EXCESS WEIGHT GAIN (CHILD)
12. The Panel emphasises the
importance of not smoking and of
avoiding exposure to tobacco smoke
13. Continuous Update Project
(CUP)
• Keep evidence, conclusions and
recommendations updated into the future
• Working with team at ICL
• Same principles:
- Systematically review evidence
- Meta analysis
- Panel of experts
-draw conclusions
-make recommendations
17. Behaviour
• People behave like those around them
– social norms
• Asking people to behave very differently
from their social norm only has limited or
unsustained effect
• Personal choice determines individual
variation around the social norm
– small effect
• External factors determine social norms
– big effect
18.
19. Everybody has a role
to play
Action needs to be
coherent
Leadership from
Government
Health professionals
20. Conclusions
The WCRF/AICR Expert Reports, and the CUP, are the
most rigorous and authoritative reviews available.
They conclude that
•
Cancer is a major cause of death, disability and lost life years
•
Cancer is mostly environmentally determined and largely
preventable
•
With smoking, food, nutrition, body fatness and physical activity
are the most important factors affecting cancer risk
•
Evidence to support this comes from many different sources
•
Preventing cancer through food, nutrition and physical activity will
also prevent other major chronic diseases
•
Changes are needed in people’s environment as well as
in personal choices
Just a note about who does what within our organisation. The charitable fundraising and information programs are conducted at a national level in four countries. And then there is the part I work for – WCRF International – which provides strategic guidance to the charities and conducts most of the science and policy work.
November 1st will see the publication of the WCRF/AICR Expert Report, Food, Nutrition, Physical Activity and the Prevention of Cancer: A Global Perspective. The report synthesizes evidence from a vast body of research, grades the quality of that evidence, and draws a series of comprehensive cancer prevention goals for populations and practical recommendations for people. It is a remarkable achievement and yet, as you will see, it is only the beginning.
For breast cancer the number of papers published in the last 6 years is about the same number as published in the previous 50 years. The CUP numbers include all those entered by end 2011
For more information refer to websites.363=/
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