Electric stimulation works by mimicking the natural way by which the body exercises its muscles. The electrodes attached to the skin deliver impulses that make the muscles contract. It is beneficial in increasing the patient's range of motion and improves the circulation of the body.
A motor point is a specific skin area where the targeted muscle is best stimulated with the smallest amount of current amplitude and the shortest pulse duration
Electric stimulation works by mimicking the natural way by which the body exercises its muscles. The electrodes attached to the skin deliver impulses that make the muscles contract. It is beneficial in increasing the patient's range of motion and improves the circulation of the body.
A motor point is a specific skin area where the targeted muscle is best stimulated with the smallest amount of current amplitude and the shortest pulse duration
Rebox electrotherapeutic method is based on non-invasive transcutaneous application of specific electric currents to a living tissue. Main indications for using the Rebox include treatment of acute and chronic pain, immobility, musculoskeletal and neurological disorders and oedema.
Knowledge about the faradic current and its physiological effects,indications and its contraindication and the methods of the application of the faradic current,motor point stimulation and its benefit used in physiotherapy
Rebox electrotherapeutic method is based on non-invasive transcutaneous application of specific electric currents to a living tissue. Main indications for using the Rebox include treatment of acute and chronic pain, immobility, musculoskeletal and neurological disorders and oedema.
Knowledge about the faradic current and its physiological effects,indications and its contraindication and the methods of the application of the faradic current,motor point stimulation and its benefit used in physiotherapy
Nerve conduction studies (NCSs) have become a simple and reliable test of peripheral nerve function.
With adequate standardization, the method now provides a means of not only objectively identifying the lesion but also precisely localizing the site of maximal involvement.
Electrical stimulation of the nerve initiates an impulse that travels along motor or sensory nerve fibers.
The assessment of conduction characteristics depends on the analysis of compound evoked potentials recorded from the muscle in the study of motor fibers and from the nerve itself in the case of sensory fiber
ELECTRICAL STIMULation of the nerve CATHODE AND ANODE: Surface electrodes, usually made of silver plate, come in different sizes, commonly in the range of 0.5 to 1.0 cm in diameter.
Stimulating electrodes consist of a cathode, or negative pole, and an anode, or positive pole, so called because they attract cations and anions.
As the current flows between them, negative charges that accumulate under the cathode, by making inside the axon relatively more positive than outside, depolarize the nerve or cathodal depolarization.
Conversely, positive charges under the anode hyperpolarize the nerve
TYPES OF STIMULATOR
Most commercially available stimulators provide a probe that mounts the cathode and the anode at a fixed distance, usually 2 to 3 cm apart.
The intensity control located in the insulated handle, though bulky, simplifies the operation for a single examiner.
The ordinary banana plugs connected by shielded cable also serve well as stimulating electrodes.
The use of a large diameter electrode for stimulation lowers current density in the skin, causing less pain, although the exact site of nerve activation becomes uncertain.
A monopolar stimulation with a small cathode placed on the nerve trunk and a large anode over the opposite surface in the same limb.
The use of a subcutaneously inserted needle as the cathode reduces the current necessary to excite the nerve compared to surface stimulation.
A surface electrode located on the skin nearby or a second needle electrode inserted in the vicinity of the cathode serves as the anode.
The maximum current during such stimulation causes neither electric nor heat damage to the tissue.
RECORDING OF MUSCLE AND NERVE POTENTIAL
Surface and Needle Electrodes:
Surface electrodes with a larger recording radius serve better than needle electrodes in assessing a compound muscle action potential (CMAP).
Its onset latency indicates the conduction time of the fastest motor fibers, and amplitude, the number of available motor axons.
A needle electrode, despite its small recording radius has its place in identifying the activity from a small muscle when surface recording fails.
Its use also improves segregation of a target activity from neighboring discharges after proximal stimulation, which tends to excite unwanted neighboring nerves simultaneously
Amplifier system
The electrodes convert bioelectric signal resulting from muscle or
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
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- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
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Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Novas diretrizes da OMS para os cuidados perinatais de mais qualidade
Waveforms..et..
1.
2.
3. Course Outline
INTRODUCTION & GENERAL CONSIDERATION
• Types of Current Used: Low Frequency Current & High Frequency Current
LOW FREQUENCY CURRENT
• Faradic Current, Sinusoidal Current, Galvanic Current, Superimposed Current, Modified Direct Current, Dia
Dynamic, Interferential Current, Bio-Feed Back, Tens, Electrodiagnosis.
HIGH FREQUENCY CURRENT
• Short Wave Diathermy, Long Wave Diathermy, Microwave, Ultrasound.
FARADIC & SINUSOIDAL CURRENT
• Introduction & Definition, Physiological Effects, Therapeutic Effects Uses, Methods & Technique of
Application, Care of Equipments, Electrodes & Rubber, Straps, Dangers & Precautions.
• Earth Shocks in Apparatus Working on Mains (b) Antiseptic Technique & Precautions.
GALVANIC
• Introduction & Definition, Physical Effect, ‘Physiological Effect & Uses’, Techniques & Methods of
Application.
• (a) Bath Treatments (b) Size & Position of Electrodes (c) Ionization:
• Theory of Medical Ionization, Proof of Medical Ionization, Effect of Various Ions: Iodine, Salicylate,
Chlorine, Albucid, Zinc, Copper, Histamine, Carbachol, Amichol, Renotin, Novacain, Lithium.
TECHNIQUE OF MEDICAL IONIZATION
• (General Technique)
• Wounds, Sinuses, The Nose, The Eye, the Ear
• Surgical Ionization: The Modified Direct Current
• Modification of Current: Interrupted Direct Current, Surged Direct Current, Physiological Effects,
Therapeutic Uses, Techniques & Methods of Application.
• Neoplasms of Articular Tissues, Torticollis, Garylion, Bursitis etc., Nervous System-Poliomyelitis,
4. SUPER IMPOSED CURRENT
• Introduction & Definition, Effects & Uses of Super Imposes Current.
• Techniques & Method of Application, Dangers & Precaution.
ELECTRICAL REACTION
• Normal & Abnormal Reactions of Muscle & Nerve to Faradism & Interrupted Galvanism,
Changes in Electrical Reaction in: Upper Motor Neuron Lesions, Lower Motor Lesion,
Muscular Diseases.
DIADYNAMIC CURRENT
• Introduction & Definition, Physiological Effects, Therapeutic Uses, Dangers & Precautions,
Techniques of Application,
INTERFERENTIAL CURRENT
• Theory of Interferential Therapy, Physiological Effects of Interference Current, Indications,
Contra Indications & Dangers, Techniques of Treatment.
BIO-FEEDBACK & IT’S DEFINITION
• Definition of Bio-Feedback, Physiological Effects Therapeutic Uses, Indications Contra
Indications & Dangers, Techniques of Application.
TRANSCUTANEOUS/ELECTRICAL NERVE STIMULATION
• Definition, Pain Modulation Theory, Technique of Application, Indication, Contra Indications &
Dangers.
5. ELECTRODIAGNOSIS
• Normal & Abnormal Reactions of Muscle & Nerve to Faradism &
Interrupted Galvanism.
CHANGES IN ELECTRICAL REACTION IN
• A Lesion of the Upper Motor Neuron, A Lesion of the Lower Motor
Neuron, Damage to the Muscle Itself, A Fault At the Neuromuscular
junction, A Functional Disorders.
• Definition of Rheobase, Chronaxie & Accommodation.
TYPES OF ELECTRICAL REACTIONS
• Normal, Complete Denervation, Partial Denervation, Myasthenic.
• Intensity Duration Curves, Theory of Intensity Duration Curve, Technique &
Plotting
• Graphs of Intensity Duration Curve, Advantages. Nerve Conduction Test,
Rheobase, Chronxie & Accomoodity Test: Faradic Interrupted Galvanic Test
(Qualitative & Quantitative).
• Nerve Conduction Velocity Test, Neurography, Repitition, Stimulation,
EMG Spontaneous & Recruitment Patterns, Indication of Nerve
Conduction Velocity & Electromyography.
6. Why use electrical modalities?
• To create muscle contraction through nerve or
muscle stimulation
• To simulate sensory nerves to help in treating
pain
• To create an electrical field in biologic tissues
to stimulate or alter the healing process.
• To create an electrical field on the skin surface
to drive ions beneficial to the healing process
into or through the skin.
6
8. • low frequency currents
– 1-1,000 pps.
– affects sensory and motor nerves
• high frequency currents
– >10,000 pps.
– no effect on sensory and motor nerves
• Medium frequency currents
– 1,000-10,000 pps.
– stimulates sensory and motor nerves
– little skin resistance
12. Pulsed Currents
MONOPHASIC CURRENT
Description:
• One-directional flow marked by
periods of non-current flow
• Electrons stay on one side of the
baseline or the other
BIPHASIC CURRENT
Description:
• Bidirectional flow of electrons marked by
periods of non-current flow
• Electrons flow on both sides of the
baseline (positive and negative)
12
13. Biphasic Current Types
Symmetrical
– Mirror images on each side of the baseline
– No net positive or negative charges under the electrodes
Balanced Asymmetrical
– The shape of the pulse allows for anodal (positive) or
cathodal (negative) effects
– No net positive or negative charge
Unbalanced Asymmetrical
– Positive or negative effects
18. 18
The shape of these
waveforms as they reach
their max. amplitude or
intensity is directly
related to the excitability
of the nervous tissue.
The more rapid the
increase in amplitude, or
the rate of rise,
the greater
the current’s ability to
excite the nervous tissue
19. The rate of rise & decay time
• The rate of rise in amplitude, or the rise time
refers to how quickly the pulse reaches its
maximum aplitude in each phase.
• Decay time refers to the time in which pulse
goes from paek amplitude to 0 V.
19
20. Pulse Duration
• The duration of each pulse indicates the length
of time current, is flowing in one cycle.
• The time (horizontal distance) from when the
pulse rises to the baseline to the point where it
terminates on the baseline.
20
Monophasic Pulse Biphasic Pulse
21. Pulse Duration
• Very short pulse durations with low intensities
can depolarize sensory nerves
• Longer pulse durations are required to
stimulate motor nerves
• Very long pulse durations with high intensities
are needed to elicit a response from a
denervated muscle.
21
22. Phase Duration
• Phases are individual portions of the pulse that appear on one side of the baseline
• For monophasic currents, pulse duration and phase duration are same (only 1 phase).
• Biphasic pulses have two phase durations so the pulse duration is dertermined by the
combined phase durations.
• The phase duration may be as short as a few microseconds or may be a long duration direct
current that flows fro several minutes.
22
1 1
Monophasic Pulse Biphasic Pulse
2
23. Interpulse Interval
• The time between the end of one pulse and the start of the next pulse
• Increasing the pulse frequency decreases the interpulse interval and vice-
versa
23
Two Monophasic Pulses Two Biphasic Pulses
24. Intrapulse Interval
• Intrapulse intervals are brief interruptions of current flow.
• Are always shorter than the interpulse interval.
• They allow for physiologic adaptations to the current
• Are normally not adjustable on the unit.
24
Biphasic Pulse
25. Pulse Frequency
• The number of times a pulse occurs per second
• With alternating currents this measure is described as cycles per second
• The muscular and nervous systems responses depend on the length of time
between pulses and on how the pulse or waveforms modulated.
• Muscles responds with individual twitch contraction to pulse rates of less than 50
pulses per second.
• At 50 pulses per second or greater a tetanic contraction will result, regardless of
whether the current is biphasic, monophasic, or polyphasic
25
26. Pulse Period
• The pulse period is the amount of time from the start of one pulse to the start of
the next pulse.
• Means the combined time of the pulse duration and the interpulse interval.
• Includes the phase durations, intrapulse interval,and interpulse interval.
• Inversely proportional to pulse frequency. As the pulse frequency increases, the
pulse period decreases and vice-versa.
26
Two Monophasic Pulses Two Biphasic Pulses
27. Pulse Trains (Bursts)
• Trains contain individual pulses
• Pulses in the train still have time-dependent characteristics:
pulse duration, interpulse interval, etc.
• Each train is separated by “off” times – the intertrain (or
interburst) interval
27
28. Pulse Charge & Phase Charge
• Refers to the total amount of electricity being
delivered to the patient during each pulse
• With monophasic current, the phase charge and the
pulse charge are the same and always greater than
zero
• In biphasic current, the pulse charge is equal to the
sum of the phase charges.
• If the pulse is symmetric, the net pulse charge is zero
28
29. Current Modulation
• Modulation refers to any alteration in the
magnitude or any variation in duration of
these pulses.
• Modulation may be continuous, interrupted,
burst or ramped.
• The parameters of this modulation must be
established according to various treatment
goals.
29
30. Pulse Ramp
• Gradually increases the current
• Produces a more natural contraction
• More comfortable
30
32. Current Flow
• Electron Flow
(shown in red)
– Between the generators and
electrodes
– To and from the generator
• Ion Flow
(shown in yellow)
– Occurs within the tissues
– Negative ions flow towards the
anode and away from the
cathode
– Positive ions flow towards the
cathode and away from the
anode
+
+
-
-
33. Electrodes
• Purpose
– Completes the circuit between the generator and body
– Interface between electron and ion flow
– Primary site of resistance to current
• Materials
– Metallic (uses sponges)
– Silver
– Carbon rubber
– Self-adhesive
34. Electrode Size
• Determines the Current Density
• Equal size
– Bipolar arrangement
– Approximately equal effects under exach
36. Current Density
• Bipolar Technique
– Equal current densities
– Equal effects under each electrode
(all other factors being equal)
• Monopolar Technique
– Unequal current densities
• At least 4:1 difference
– Effects are concentrated under the smaller electrode
• “Active” electrode(s)
– No effects under larger electrode
• “Dispersive” electrode
• Quadripolar Technique
– Two bipolar electrode arrangements
– Two independent electrical channels
– TENS is a common example
“Active” “Dispersive”
37. Electrode Proximity
• Determines the number
of parallel paths
• The farther apart the
electrodes the more
parallel paths are formed
• More current is required
to produce effects as the
number of paths
increases
38. Stimulation Points
• Motor Points
– Superficial location of motor nerve
– Predictably located
– Motor nerve charts
• Trigger Points
– Localized, hypersensitive muscle spasm
– Trigger referred pain
– Arise secondary to pathology
• Acupuncture Points
– Areas of skin having decreased electrical resistance
– May result in pain reduction
• Traumatized Areas
– Decreased electrical resistance (increased current flow)
39. Path of Least Resistance
• Ion flow will follow the path of
least resistance
– Nerves
– Blood vessels
• The current usually does not
flow from electrode-to-
electrode (the shortest path)
• The path of least resistance is
not necessarily the shortest
path
40. Selective Stimulation of Nerves
• Nerves always depolarize in the same order
– Sensory nerves
– Motor nerves
– Pain nerves
– Muscle fiber
• Based on the cross-sectional diameter
– Large-diameter nerves depolarize first
• Location of the nerve
– Superficial nerves depolarize first
41. Phase Duration and
Nerve Depolarization
• Phase duration selectively depolarizes tissues
Phase Duration Tissue
Short Sensory nerves
Medium Motor nerves
Long Pain nerves
DC Muscle fiber
42. Adaptations
• Patients “get used” to the treatment
• More intense output needed
• Habituation
– Central nervous system
– Brain filters out nonmeaningful, repetitive information
• Accommodation
– Peripheral nervous system
– Depolarization threshold increases
• Preventing Adaptation
– Vary output (output modulation) to prevent
– The longer the current is flowing, the more the current must be
modulated.
44. Motor-level Stimulation
Comparison of Voluntary and Electrically-Induced Contractions
Voluntary
• Type I fibers recruited
first
• Asynchronous
– Decreases fatigue
• GTO protect muscles
Electrically-induced
• Type II fibers recruited
first
• Synchronous
recruitment
– Based on PPS
• GTOs do not limit
contraction
45. Motor-level Stimulation
• Parameters:
Amplitude: Contraction strength increases as
amplitude increases
Phase duration: 300 to 500 µsec targets motor
nerves:
– The shorter the phase duration, the more amplitude
required
– Longer durations will also depolarize pain nerves
– Pain often limits quality and quantity of the contraction
Pulse frequency: Determines the type of contraction
46. Pulse Frequency
• Frequency determines the time for mechanical
adaptation
• Lower pps allows more time (longer interpulse
interverals)
Label Range Result
Low < 15 pps* Twitch: Individual contractions
Medium 15-40 pps* Summation: Contractions blend
High >40 pps* Tonic: Constant contraction
* Approximate values. The actual range varies from person-to-person and
between muscle groups
47. Effect of Pulse Frequency on Muscle
Contractions
1 pulse per second
Twitch Contraction
The amount of time
between pulses – the
interpulse interval – is
long enough to allow the
muscle fibers to return to
their original position
20 pulses per second
Summation
The amount of time
between pulses allows
some elongation of the
fibers, but not to their
starting point.
40 pulses per second
Tonic Contraction
The current is flowing so
rapidly that there is not
sufficient time to allow the
fibers to elongate
49. Pain Control
Sensory-level Motor-Level Noxious Level
Target A-beta fibers Motor nerves A-delta
Tissue C fibers
Phase < 60 µsec 120 to 250 µsec 1 msec
Duration
Pulse 60 to 100 pps 2 to 4 pps Variable
Frequency 80 to 120 pps
Intensity Submotor Moderate to To tolerance
Strong contraction
51. Edema Control
• Cathode placed over
injured tissues
• High pulse frequency
• Submotor intensity
• Thought to decrease
capillary permeability
• Do not use if edema has
already formed
52. Edema Reduction
• Muscle contractions
“milk” edema from
extremity
• Electrodes follow the
vein’s path
• Alternating rate targets
muscle groups
• Elevate during treatment
55. Contraindications and Precautions
• Areas of sensitivity
– Carotid sinus
– Esophagus
– Larynx
– Pharynx
– Around the eyes
– Temporal region
– Upper thorax
• Severe obesity
• Epilepsy
• In the presence of
electronic monitoring
equipment
• Cardiac disability
• Demand-type pacemakers
• Pregnancy (over lumbar and
abdominal area)
• Menstruation (over lumbar
and abdominal area)
• Cancerous lesions (over
area)
• Sites of infection (over area)
• Exposed metal implants
56. Current density
• Amount of current flow per cubic volume
– If the electrodes are place closely together, the
area of highest current density is relatively
superficial.
– If the electrodes are spaced farther apart the
current density will be higher in deeper tissues,
including nerve and muscles.
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57. Electrode size
& Placement
• Electrode size and placement are key elements which the therapist controls
that will have great influence on results.
• Electrode size will also change current intensity
• If one electrode is larger and the other is smaller, the current density beneath
the smaller electrode is increased.
• Using a large (dispersive) electrode remote form the treatment area while
placing a smaller (active) electrode as close as possible to the nerve or
muscle motor point will gibe greatest effect at the small electrode.
• The larger electrode disperses the current over the large area
• The small electrode concentrates the current in the area of the motor point
• High current density close to the neural structure makes it more certain that
the treatment will be successful with the least amount of current.
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