NEURO CYSTICERCOSIS

1. NARASARAOPETA INSTITUTE
OF PHARMACEUTICAL SCIENCES
Case presented by
VARUN TEJ

2.  Subjective.
 Objective.
 Assessment.
 Plan.
 Treatment goals.
 Monitoring parameters.
 Patient counseling.
 References.
Department of Pharamacy Practise. 2

3. Mr. xxxxxx of 37 years old male patient was admitted in
hospital on 19/11/2015 with chief complaints of one
episode of seizures in sleep at morning 5 A.M, other
episode seen yesterday.
Associated complications were
• Frothing.
• Mouth deviation.
• Tightness of both upper limbs.
• General weakness.
PMH : SEIZURES since one year.
Department of Pharamacy Practise. 3

4.  B.P : 120/80 mm Hg.
 P.R : 96 beats/minute.
 R.R : 28 cycles/minute.
 SpO2 : 98 % on room air.
 C.V.S : S1 , S2 (+).
 R.S : BAE (+).
 Abdomen : Soft.
 Temp : Afebrile.
Department of Pharamacy Practise. 4

5. Investigations were done like
 Complete blood picture.
 Serum electrolytes.
 CECT – BRAIN.
All laboratory parameters were in normal range.
TEST RESULT NORMAL RANGE
W.B.C 15.4 103/mm3 4.1 – 10.5
Department of Pharamacy Practise. 5

6. Report of CECT – BRAIN was
 Granulomatous disease with mild perilesional edema in
right frontal lobe.
 Moderate size gliosis in right temporal lobe.
Department of Pharamacy Practise. 6

7. Etiology :
 The main cause of seizures was due to Neuro
cysticercosis.
From subjective and objective evidences and also some
case relevant studies, an assessment was made and
patient was diagnosed and treated for NEURO
CYSTICERCOSIS and secondary for SEIZURES.
Department of Pharamacy Practise. 7

8. BRAND NAME GENERIC NAME DOSE ROUTE FREQUENCY
Inj. Epsolin Phenytoin 50 mg IV TID
Inj. Decadran Dexamethasone 2 ml IV BID
Inj. Taxim Cefotaxim 1 gm IV BID
Inj. Pantin Pantoprazole 40 mg IV OD
IV. Fluids Normal saline IV OD
Department of Pharamacy Practise. 8

9.  On this day patient vitals were normal.
 Patient condition was improved better than previous
day.
 Same therapeutic plan was continued with an addition
of a new drugs.
BRAND NAME GENERIC NAME DOSE ROUTE FREQUENCY
Tab. Zental Albendazole 400 mg ORAL BID
Tab. Wysoline Prednisolone 10 mg ORAL BID
Department of Pharamacy Practise. 9

10.  All vitals were normal.
 Patient condition was
improved.
 Same therapeutic plan
was continued…….
 All vitals were normal.
 No seizures.
 No further complaints.
 Condition was improved.
Department of Pharamacy Practise. 10

11.  All vitals were normal.
 All complaints became nil.
 Patient was discharged with suitable discharge
medication with review after 15 days.
BRAND NAME GENERIC NAME DOSE FREQUENCY
Inj. Pantin Pantoprazole 40 mg OD
Tab. Wysoline Prednisolone 10 mg BID
Tab. Zental Albendazole 400 mg BID
Inj. Epsolin Phenytoin 100 mg OD
Department of Pharamacy Practise. 11

12.  To treat Granulomatous disease.
 To clear Perilesional edema.
 To prevent reoccurrence of seizures.
Department of Pharamacy Practise. 12

13.  On day – 2 tab. Zental 400 mg (Albendazole) was
prescribed because it was an Anthelmintic which was
used to parasitic infection.
 Tab. Wysoline (prednisolone) was added. It was an
anti inflammatory agent.
Department of Pharamacy Practise. 13

14. Disease monitoring parameters
Monitor patient behavior.
Monitor seizures.
Drug monitoring parameters
Phenytoin :
 Monitor patient behavior.
Dexamethasone & Prednisolone :
 Monitor corticosteroid effectiveness.
Department of Pharamacy Practise. 14

15.  Maintain hygienic conditions.
 Improved sanitation.
 Intake of low protein diet.
 Don’t eat raw & improperly cooked food.
 Maintain regular prescribed medication.
 Don’t take the double dose at a time when you skip the
medication.
Department of Pharamacy Practise. 15

16.  Joseph T. Dipiro, Pharmacotherapy A pathological
approach, 8th edition, Mc Graw Hill, New York. Pg.no :
943.
 CIMS July – Oct. 2015.
 Drug Index July – Sept. 2011.
 www.Drugs.com.
Department of Pharamacy Practise. 16

17. Department of Pharamacy Practise. 17