The vagus nerve is the 10th cranial nerve that passes through the head and neck. It is the longest nerve of the parasympathetic nervous system. The vagus nerve emerges from the medulla, passes through the jugular foramen, and descends in the neck giving off several branches that supply structures in the head and neck like the pharynx, larynx, outer ear, and meninges. It is a mixed nerve responsible for motor, sensory, and parasympathetic functions. Injuries and irritation of its branches can cause issues like hoarseness, cough, or dysphagia.
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FACIAL NERVE AND IT'S APPLIED ANATOMY AND IT'S SIGNIFICANCE FOR A DENTIST ALONG WITH THE CAUTIONS TO AVOID AN IATROGENIC INJURY TO FACIAL NERVE AND THE MANAGEMENT OF A PATIENT OF FACIAL NERVE DISORDER DURING ENDODONTIC PROCEDURES
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FACIAL NERVE AND IT'S APPLIED ANATOMY AND IT'S SIGNIFICANCE FOR A DENTIST ALONG WITH THE CAUTIONS TO AVOID AN IATROGENIC INJURY TO FACIAL NERVE AND THE MANAGEMENT OF A PATIENT OF FACIAL NERVE DISORDER DURING ENDODONTIC PROCEDURES
SEMINAR V & VI TRIGEMINAL NERVE AND ITS CLINICAL IMPORTANCE FINAL.pptxPrem Chauhan
TRIGEMINAL NERVE AND ITS CLINICAL IMPORTANCE
The IASP defines TRIGEMINAL NEURALGIA as an often unilateral orofacial pain disorder that presents as brief and recurrent episodes of an electric shock-like pain and is limited in distribution to one or more divisions of the trigeminal nerve.
Fothergill’s disease/tic douloureux
The anatomy of the nerve supply of the head and neck has many significant applications in maxillofacial surgery. Understanding these important anatomic relations- variations enables surgeons to perform the surgical procedures safely. Knowledge of these concepts helps us to recognize the problems and complications as and when they occur and manage them accordingly.
this presentation consist of introduction to types of nerves, structure of nerve and cranial nerves. there is a detail description about, origin , course of the trigeminal nerve and its branches and the structures supplying the nerve. it also contains applied anatomy of the nerve and its importance of the nerve in oral and maxillofacial surgeries. a detail description about the examination of the trigeminal nerve is also mentioned in the presentation. hoping that it would be useful to the students and people seeking for knowledge about the trigeminal nerve.
SEMINAR V & VI TRIGEMINAL NERVE AND ITS CLINICAL IMPORTANCE FINAL.pptxPrem Chauhan
TRIGEMINAL NERVE AND ITS CLINICAL IMPORTANCE
The IASP defines TRIGEMINAL NEURALGIA as an often unilateral orofacial pain disorder that presents as brief and recurrent episodes of an electric shock-like pain and is limited in distribution to one or more divisions of the trigeminal nerve.
Fothergill’s disease/tic douloureux
The anatomy of the nerve supply of the head and neck has many significant applications in maxillofacial surgery. Understanding these important anatomic relations- variations enables surgeons to perform the surgical procedures safely. Knowledge of these concepts helps us to recognize the problems and complications as and when they occur and manage them accordingly.
this presentation consist of introduction to types of nerves, structure of nerve and cranial nerves. there is a detail description about, origin , course of the trigeminal nerve and its branches and the structures supplying the nerve. it also contains applied anatomy of the nerve and its importance of the nerve in oral and maxillofacial surgeries. a detail description about the examination of the trigeminal nerve is also mentioned in the presentation. hoping that it would be useful to the students and people seeking for knowledge about the trigeminal nerve.
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
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Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
2. INTRODUCTION
SURFACE MARKING
GANGLIONS
FUNCTIONAL COMPONENTS
NUCLEI
COURSE AND RELATIONS
BRANCHES
AREAS SUPPLIED IN THE HEAD AND NECK
CLINICAL ANATOMY
REVISION
3.
4.
5.
6. INTRODUCTION
▶ 10th cranial nerve
▶ So called due to its vague course through the head, neck, thorax and
the abdomen.
▶ Longest nerve of the autonomic nervous system in the body
▶ MIXED NERVE: sensory, motor and parasympathetic
▶ Fibres of the cranial root of accessory nerve are also distributed through it.
▶ Primarily associated with the parasympathetic division of the autonomic
nervous system, however, it also has some sympathetic influence through
peripheral chemoreceptors.
▶ Associated with the derivatives of the fourth pharyngeal arch.
7.
8. SURFACE MARKING:
▶ Runs along the posteromedial side of Internal Jugular Vein
▶ Marked by 2 points :
1. Antero-inferior part of tragus
2. Medial end of the clavicle
11. GANGLIA ASSOCIATED
SUPERIOR/JUGULAR
LIES WITHIN THE JUGULAR FORAMEN
ROUNDED
SMALLER IN SIZE
Connected to IX, XI and to
Superior Cervical Ganglion
1.MENINGEAL
2.AURICULAR
INFERIOR/GANGLION NODASUM
BELOW THE JUGULAR FORAMEN-
NEAR THE SKULL BASE
CYLINDRICAL (2.5 cm)
LARGER
Joined by cranial root of XI; connected to
XII, superior cervical ganglion
1. PHARYNGEAL
2.CAROTID
3.SUPERIOR LARYNGEAL
4.RECURRENT LARYNGEAL 5.CARDIAC
12.
13.
14. NUCLEI:
Within the medulla oblongata of the brainstem, there are 4 vagal nuclei, onto
which axons of the vagus nerve emerge from or converge onto:
1. NUCLEUS AMBIGUOUS (BRANCHIOMOTOR):
2. DORSAL MOTOR NUCLEUS (PARASYMAPATHETIC)
3. NUCLEUS OF TRACTUS SOLITARIS: (GUSTATORY)
4. NUCLEUS OF SPINAL TRACT OF TRIGEMINAL
15. Functional components
Specifically, the vagus nerve contains:
1. Special visceral efferent (motor) fibers.
2. General visceral efferent (motor) fibers
3. General visceral afferent (sensory) fibers
4. Special visceral afferent (sensory) fibers
5. General Somatic Afferent Fibres
16.
17. It is responsible for not only
carrying motor signals to the
organs it innervates, but it also
carries sensory information
from these organs back to the
central nervous system
20. INTRACRANIAL
Lateral aspect of
medulla;between olivary
nucleus and ICP
Nerve attached to 10
rootlets to Posterolateral
sulcus of medulla
Rootlets unite –Single trunk
Laterally across the jugular
tubercle along with IX, XI
Nerve is enclosed within the same dural sheath as the 11th
Nerve; 9th CN lies within a separate dural sheath.
21.
22. Leaves the cranial cavity by
passing through the middle
part of jugular foramen
In the foramen, joined by
the cranial root of the
accessory nerve.
25. Right Vagus in front of
Right Subclavian Artery
Left Vagus between
left common carotid
and left subclavian
arteries
Enter the
Thorax
Root of the neck
26.
27. Both the ganglia contain cell bodies
of sensory fibres of vagus nerve.
Internal branch of Accessory Nerve
unites with Vagus just above its
inferior ganglion; transfers all the
fibres to VAGUS
31. 1. MENINGEAL BRANCH
Arises from
Superior Ganglion
Passes back
through Jugular
Foramen
Supplies duramater
of posterior cranial
fossa
SUPPLIES:
• Duramater of Posterior Cranial Fossa
32.
33. 2. AURICULAR/ARNOLD’S NERVE
Arises from
Superior
Ganglion
Re-enters the
lateral portion
of the jugular
foramen via
the mastoid
canaliculus
Exits again
through the
tympanomast
oid suture of
the temporal
bone
Reaches and
supplies the
skin.
SUPPLIES:
• Concha, root of the auricle
• posterior half of the external auditory meatus
• Tympanic membrane
35. 3. PHARYNGEAL
LOWER PART
OF INFERIOR
GAMGLION
PASSES
BETWEEN
EXTERNAL AND
INTERNAL
CAROTID
ARTERIES
REACHES THE
MIDDLE
CONSTRICTOR
OF PHARYNX
FORMS THE
PHARYNGEAL
PLEXUS
Supplies:
• Muscles of pharynx(except the stylopharyngeus muscle)
• Muscles of soft palate (except tensor palatini muscle)
40. 4.SUPERIOR LARYNGEAL NERVE
Arise from
the inferior
ganglion of
the vagus
nerve.
Moves
forwards
on the
superior
constrictor
Passes
between the
external and
internal
carotid
arteries
At the tip of
the hyoid
bone, divides
into external
and internal
branches,
41.
42. A. EXTERNAL LARYNGEAL NERVE
Accompanies
the Superior
Thyroid
Artery
Pierces the
inferior
Constrictor
Supplies
CRICOTHYROID
Also branches to
inferior
constrictor +
pharyngeal plexus
All other intrinsic
laryngeal muscles
are innervated by
recurrent laryngeal
nerve
MOTOR
43.
44. B. INTERNAL LARYNGEAL NERVE
Supplies the mucous membrane of larynx ABOVE the level of vocal cords
PASSES
DOWNWARDS
AND
FORWARDS
PIERCES
thyrohyoid
membrane
Enters the
larynx
SENSORY
45. 5. INFERIOR/Recurrent laryngeal
nerve
Arises from
in front of
RIGHT
SUBCLAVIA
N ARTERY
Winds
backwards
below the
artery
Runs
upwards
behind
SUBCLAVIA
N AND
COMMON
CAROTID
ARTERIES
Reach the
trachea-
oesophagea
l groove;
related to
Inferior
Thyroid
Artery
Passses
deep to the
lower
border of
the
INFERIOR
CONSTRICT
OR
Enters
larynx
behind the
CRICOTHYR
OID JOINT
a. RIGHT RECURRENT LARYNGEAL
49. Arises from
Vagus in the
thorax
Loops
around
Ligamentum
arteriosum
Reaches the
tracheooeso
phagal
groove
Usually
posterior to
the inferior
thyroid
artery
Supplies:
• Similar distribution as Right RL
b. LEFT RECURRENT LARYNGEAL
50. 6. Cardiac branches
branches
off :
Superior
and
Inferior
Total 4 :Out of which
the three go to the
deep cardiac plexus
Left inferior
goes to
superficial
cardiac
plexus
51.
52. CLINICAL ANATOMY
▶ The Vagus nerve is tested clinically by comparing the palatal arches on the two sides.
▶ On the paralysed side, there is no arching, and the uvula is pulled to the normal side.
1. Nasal regurgitation
2. Nasal twang in voice
3. Hoarseness of voice
4. Flattening of the palatal arch
5. Cadaveric position of the vocal cord
6. Dysphagia
Paralysis of vagus nerve
53.
54. ▶ Irritation of the auricular branch of vagus in the external ear
persistent cough, vomiting, or death (due to sudden cardiac inhibiton)
▶ Stimulation of the auricular branch increased appetite
▶ Irritation of the recurrent laryngeal nerve by enlarged lymph nodes In
children persistent cough
▶ Injury to recurrent laryngeal nerve hoarseness and dysphonia due
to paralysis of the right vocal cord.
▶ Injury to pharyngeal nerve dysphagia.
55. ▶ Some fibres in the geniculate ganglion of facial
nerve pass into the vagus through communications
between the two nerves.
▶ They reach the skin of auricle through the auricular
branch of vagus.
▶ Sometimes a sensory ganglion may have a viral
infection and vesicles appear on the area of skin
supplied by the ganglion.-HERPES ZOSTER.
▶ In herpes zoster of the geniculate ganglion,
vesicles appear on the skin of auricle.
56. VAGAL NERVE STIMULATION
• ▶ A medical treatment that involves delivering electrical impulses
to the vagus
• ▶ Used as an adjunctive treatment for certain types of intractable
epilepsy
• and treatment-resistant depression.