The Participant Recruitment Service at UCSF is preparing for launch with a soft launch phase involving developing recruitment materials, piloting recruitment services for 4 studies, creating a participant registry database, and conducting passive recruitment from the Integrated Data Repository database. The PRS aims to centralize recruitment efforts and address challenges like limited coordinator time, uncoordinated multi-site efforts, and lack of diversity in clinical trials. The soft launch will test recruitment materials, registry, and services to help enroll more research participants.

1. PRS – Preparing for Launch Nariman A. Nasser, Director Participant Recruitment Service Clinical & Translational Science Institute University of California, San Francisco

3. Addressing the Needs

4. Participant Recruitment Service Model

6. Challenges Coordinators have limited time and are not properly equipped to conduct recruitment Recruitment efforts across units, departments and institutions are uncoordinated and costly More than 80% of clinical trials are delayed due to recruitment Lack of diversity in clinical trials can lead to disparities in effectiveness in the marketplace

7. Poor Recruitment Experience

9. Provide expertise in recruitment materials development

10. Ensure materials meet regulatory guidelines and requirements

11. Offer an economy of scale for many recruitment activities

12. Use established vendor relationships

13. Increase the volume of high quality volunteers

15. Soft Launch Recruitment Materials Toolkit Pilot Recruitment Services (4 studies) Pilot Participant Registry Pilot Passive Database Recruitment

17. CHR pre-approved with accompanying guidance

18. Accessible from PRS Virtual Home at no cost

19. Printable via Documents, Media & Mail portal

20. Link to CTSI-branded DMM portal from VH

21. Selection of 5 designs with custom color palettes

23. Interventional clinical trial

24. Pediatric study or clinical trial

25. Poster

26. Postcard

27. Brochure

28. Newspaper advertisement

31. Anticoagulation therapy dosing – Warfarin

32. Characterization of Asthma

34. Full cohort/competing study/recruitment analysis and recruitment plan

35. Recruitment plan implementation

36. Call center (internal & external)

37. Study-specific advertising & presentation materials

38. Ad placement

39. OmniScience mobile partnership

41. Includes brief health history

42. Excellent source of “healthy” volunteers

43. Developed on SalesForce platform

44. Populated from 2 sources

45. Study-specific advertisements for pilot services studies

47. “Passive” waiver of consent on admission

48. Use ICD-9 codes, Rx, demographics to identify aggregate cohorts

49. PRS will act as HIPPA broker to obtain de-identified data and contact information

50. Contact potential participants via letter