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New ways to better Healthcare Research

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At the DayOne Experts even - Next Generation Clinical Trials, Lars G. Hemkens from University Hospital Basel shared his experience on how integrating data, that has been collected on a routine basis, into clinical trials will make a difference.

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New ways to better Healthcare Research

  1. 1. MORE USEFUL EVIDENCE NEW WAYS TO BETTER HEALTHCARE RESEARCH Lars G. Hemkens Basel, 25 June 2019 PD Dr. med. Lars G. Hemkens MPH Senior Scientist and Deputy Director Basel Institute for Clinical Epidemiology and Biostatistics (ceb) University of Basel | Department of Clinical Research University Hospital Basel | Spitalstrasse 12 | CH-4031 Basel | Switzerland QUEST (Quality | Ethics | Open Science | Translation) Visiting Fellow Berlin Institute of Health (Charité and Max Delbrück Center) | Berlin | Germany
  2. 2. 1. More useful traditional evidence 2. Future evidence: RCD & Digital Trials 3. New challenges: Clinical Cancer Epidemiology Research Focus More useful evidence – new ways to better healthcare research
  3. 3. "Data collection under real-world circumstances maximizes representativeness and generalizability, minimizes costs and effort, and allows the capture of information in large populations and many clinical events in large data sets that are continuously updated and cover long periods." Hemkens et al. CMAJ 2016
  4. 4. Randomized Real World Evidence RCD for RCT
  5. 5. RCD for RCT - Framework Mc Cord et al. Trials 2018
  6. 6. Mc Cord et al. CMAJ Open 2019 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375253/pdf/cmajo.20180096.pdf RCD for RCT – Empirical data
  7. 7. Mc Cord et al. Trials 2018 RCD for RCT Challenges / Opportunities
  8. 8. Special Thanks Lars.Hemkens@usb.ch @LGHemkens

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