The NHLBI REDS-III program uses electronic health record databases to conduct transfusion medicine research. REDS-III collects donor, blood product, and recipient data from multiple hospitals and blood centers in the US and abroad. This document outlines REDS-III's research goals, institutional infrastructure, data flow process, and planned studies including evaluating transfusion outcomes in elderly patients, severe transfusion reactions, and genetic factors influencing red blood cell storage capacity. A pilot matched donor, product, and recipient data from one hospital to demonstrate REDS-III's database approach for conducting epidemiological analyses and identifying predictors of transfusion.
Red cell alloimmunization in blood transfusion dependent Patients with Sickle...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Heparin-Induced Thrombocytopenia (HIT) is a highly prothrombotic disorder mediated by strong platelet-activating antibodies against multi molecular complexes of platelet factor4 and heparin, leading to consumptive thrombocytopenia and potentially devastating thromboembolic complications. Three alternative anticoagulants have been approved for the treatment of HIT: lepirudin, argatroban, and danaparoidsodium. We present a case of multiple organ embolism secondary to heparin-induced thrombocytopenia after IABP insertion in a cardiac shock secondary to acute myocardial infarction and our fi rst experience with the use of a novel oral anticoagulant, rivaroxaban, to treat a case of HIT-associated thrombosis after IABP insertion.
Red cell alloimmunization in blood transfusion dependent Patients with Sickle...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Heparin-Induced Thrombocytopenia (HIT) is a highly prothrombotic disorder mediated by strong platelet-activating antibodies against multi molecular complexes of platelet factor4 and heparin, leading to consumptive thrombocytopenia and potentially devastating thromboembolic complications. Three alternative anticoagulants have been approved for the treatment of HIT: lepirudin, argatroban, and danaparoidsodium. We present a case of multiple organ embolism secondary to heparin-induced thrombocytopenia after IABP insertion in a cardiac shock secondary to acute myocardial infarction and our fi rst experience with the use of a novel oral anticoagulant, rivaroxaban, to treat a case of HIT-associated thrombosis after IABP insertion.
Iron Deficiency : An Overlooked Aspect of Heart Failure Managementmagdy elmasry
Iron deficiency: a comorbidity that goes unnoticed in heart failure.Optimization of heart failure treatment.
Types of iron deficiency.Absolute ID &Functional ID.Iron Deficiency in Heart Failure :
A Therapeutic Target
Iron therapy for the treatment of iron deficiency
in chronic heart failure: intravenous or oral?
American Red Cross Campaign Strategy PresentationNoah Wilson
Developed a campaign strategy for the American Red Cross to address severe blood shortages that occur every year. Also formulated specific message, media and promotional plans. To accomplish this goal, we extensively researched the problem and current efforts to address it, as well as analyzed consumer behavior.
In this new edition of Journal of Operations and Supply Chain Management (JOSCM), the first four papers are part of our ongoing process of publishing research papers in topics related to supply chain management and logistics that raise new research insights. In addition, JOSCM also presents three best papers award nominated in the XX Simpósio de Administração da Produção, Logística e Operações Internacionais (SIMPOI 2017), which occurs annually in Sao Paulo bringing together academic and practitioners in the Operations Management field.
Power point presentation about general principles of organ transplantation and pioneer surgons and investigators, Specific discussion about Heart, Heart lung and Lung transplantation is given
Iron Deficiency : An Overlooked Aspect of Heart Failure Managementmagdy elmasry
Iron deficiency: a comorbidity that goes unnoticed in heart failure.Optimization of heart failure treatment.
Types of iron deficiency.Absolute ID &Functional ID.Iron Deficiency in Heart Failure :
A Therapeutic Target
Iron therapy for the treatment of iron deficiency
in chronic heart failure: intravenous or oral?
American Red Cross Campaign Strategy PresentationNoah Wilson
Developed a campaign strategy for the American Red Cross to address severe blood shortages that occur every year. Also formulated specific message, media and promotional plans. To accomplish this goal, we extensively researched the problem and current efforts to address it, as well as analyzed consumer behavior.
In this new edition of Journal of Operations and Supply Chain Management (JOSCM), the first four papers are part of our ongoing process of publishing research papers in topics related to supply chain management and logistics that raise new research insights. In addition, JOSCM also presents three best papers award nominated in the XX Simpósio de Administração da Produção, Logística e Operações Internacionais (SIMPOI 2017), which occurs annually in Sao Paulo bringing together academic and practitioners in the Operations Management field.
Power point presentation about general principles of organ transplantation and pioneer surgons and investigators, Specific discussion about Heart, Heart lung and Lung transplantation is given
Building Your Professional Network with LinkedInCTSI at UCSF
Presentation by Erik Wieland, Applications Manager at UCSF IT, as part of the "UCSF Profiles & LinkedIn Bootcamp for Researchers, Faculty, Staff" on 2/9/2015.
Data Reproducibility in Preclinical Discovery, Is It a Real Problem? 09/17/15CTSI at UCSF
On Sep 17th Catalyst brought a panel of academic and industry thought leaders for a lively discussion on the issue of data reproducibility in academic research. Moderated by Cathy Tralau-Stewart, head of the Therapeutics track of the Catalyst Awards, the panel explored causes and potential solutions for a problem that has been receiving national attention in both scientific and popular media.
Panelists included Keith Yamamoto, Vice Chancellor for Research at UCSF; Larry Tabak, Principle Deputy Director, NIH; John Ioannidis, Professor of Health Research Policy at Stanford School of Medicine; Elizabeth Iorns, Co-Founder, Science Exchange; Parker B. Antin, Board of Directors President, FASEB; Amanda Halford, MBA, VP of Research, Sigma-Aldrich.
http://ctsi.ucsf.edu/news/about-ctsi/data-reproducibility-preclinical-research-and-discovery
How to Harness the Power of Google Analytics, Email Marketing & Vanity to Inc...CTSI at UCSF
40 minute presentation by Nooshin Latour (@nooshin) & Anirvan Chatterjee (@anirvan) at the UC Computing Services Conference (UCCSC 2014). Evolution of UCSF Profiles research networking system, early promotion at launch, growth/SEO, and engagement with targeted personalized data emails. Full description here: https://uccsc.ucsf.edu/node/101
VIVO 2014: Google Analytics, Email Marketing & Vanity to Increase User Engage...CTSI at UCSF
Poster presented at VIVO 2014 conference: Utilized UCSF Profiles web analytics data to deliver a customized “UCSF Profiles Annual Report” to individual researchers at UCSF, which listed their total annual unique pageviews, broken down by major relevant categories (e.g. pageviews from the UCSF campus, NIH, pharmaceutical companies, foundations, and other universities). Result: Increase in user engagement and edite Profiles pages. UCSF-CTSI Team: Nooshin Latour, MA, Sr. Communications & Marketing Manager and Anirvan Chatterjee, Director of Data Strategy
UCSF Informatics Day 2014 - Keith R. Yamamoto, "Precision Medicine"CTSI at UCSF
Keith R. Yamamoto, PhD — Opening Remarks – Precision Medicine
Vice Chancellor for Research
Executive Vice Dean of the School of Medicine
Professor of Cellular and Molecular Pharmacology
UCSF
This presentation discusses the latest evidence for blood transfusion triggers in the intensive care unit of various clinical condition including severe sepsis, GI bleed, post surgical cases, and post cardiac surgery among other cnditions
Background: The aim of this pilot study was to compare the three currently available on-line hemodiafiltration techniques: Mid-Dilution (MID), Post-Dilution (POST) and Pre-Dilution (PRE) concerning middle molecular solute removal and tolerability in reference to intradialytic stability of hemodynamic parameters as well as patient wellness.
AMIA Joint Summits 2017: Building Research Data Mart from UCSF OMOP Database ...CTSI at UCSF
Poster presented at AMIA 2017 Joint Summits on Translational and Clinical Informatics.
In this research data delivery project, we explored a less traveled path of building a clinical “data mart” for a registry study on kidney transplant patients based on our institutional OMOP database.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
DERIVATION OF MODIFIED BERNOULLI EQUATION WITH VISCOUS EFFECTS AND TERMINAL V...Wasswaderrick3
In this book, we use conservation of energy techniques on a fluid element to derive the Modified Bernoulli equation of flow with viscous or friction effects. We derive the general equation of flow/ velocity and then from this we derive the Pouiselle flow equation, the transition flow equation and the turbulent flow equation. In the situations where there are no viscous effects , the equation reduces to the Bernoulli equation. From experimental results, we are able to include other terms in the Bernoulli equation. We also look at cases where pressure gradients exist. We use the Modified Bernoulli equation to derive equations of flow rate for pipes of different cross sectional areas connected together. We also extend our techniques of energy conservation to a sphere falling in a viscous medium under the effect of gravity. We demonstrate Stokes equation of terminal velocity and turbulent flow equation. We look at a way of calculating the time taken for a body to fall in a viscous medium. We also look at the general equation of terminal velocity.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Toxic effects of heavy metals : Lead and Arsenicsanjana502982
Heavy metals are naturally occuring metallic chemical elements that have relatively high density, and are toxic at even low concentrations. All toxic metals are termed as heavy metals irrespective of their atomic mass and density, eg. arsenic, lead, mercury, cadmium, thallium, chromium, etc.
ESR spectroscopy in liquid food and beverages.pptxPRIYANKA PATEL
With increasing population, people need to rely on packaged food stuffs. Packaging of food materials requires the preservation of food. There are various methods for the treatment of food to preserve them and irradiation treatment of food is one of them. It is the most common and the most harmless method for the food preservation as it does not alter the necessary micronutrients of food materials. Although irradiated food doesn’t cause any harm to the human health but still the quality assessment of food is required to provide consumers with necessary information about the food. ESR spectroscopy is the most sophisticated way to investigate the quality of the food and the free radicals induced during the processing of the food. ESR spin trapping technique is useful for the detection of highly unstable radicals in the food. The antioxidant capability of liquid food and beverages in mainly performed by spin trapping technique.
Nucleophilic Addition of carbonyl compounds.pptxSSR02
Nucleophilic addition is the most important reaction of carbonyls. Not just aldehydes and ketones, but also carboxylic acid derivatives in general.
Carbonyls undergo addition reactions with a large range of nucleophiles.
Comparing the relative basicity of the nucleophile and the product is extremely helpful in determining how reversible the addition reaction is. Reactions with Grignards and hydrides are irreversible. Reactions with weak bases like halides and carboxylates generally don’t happen.
Electronic effects (inductive effects, electron donation) have a large impact on reactivity.
Large groups adjacent to the carbonyl will slow the rate of reaction.
Neutral nucleophiles can also add to carbonyls, although their additions are generally slower and more reversible. Acid catalysis is sometimes employed to increase the rate of addition.
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...Travis Hills MN
Travis Hills of Minnesota developed a method to convert waste into high-value dry fertilizer, significantly enriching soil quality. By providing farmers with a valuable resource derived from waste, Travis Hills helps enhance farm profitability while promoting environmental stewardship. Travis Hills' sustainable practices lead to cost savings and increased revenue for farmers by improving resource efficiency and reducing waste.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
The ability to recreate computational results with minimal effort and actionable metrics provides a solid foundation for scientific research and software development. When people can replicate an analysis at the touch of a button using open-source software, open data, and methods to assess and compare proposals, it significantly eases verification of results, engagement with a diverse range of contributors, and progress. However, we have yet to fully achieve this; there are still many sociotechnical frictions.
Inspired by David Donoho's vision, this talk aims to revisit the three crucial pillars of frictionless reproducibility (data sharing, code sharing, and competitive challenges) with the perspective of deep software variability.
Our observation is that multiple layers — hardware, operating systems, third-party libraries, software versions, input data, compile-time options, and parameters — are subject to variability that exacerbates frictions but is also essential for achieving robust, generalizable results and fostering innovation. I will first review the literature, providing evidence of how the complex variability interactions across these layers affect qualitative and quantitative software properties, thereby complicating the reproduction and replication of scientific studies in various fields.
I will then present some software engineering and AI techniques that can support the strategic exploration of variability spaces. These include the use of abstractions and models (e.g., feature models), sampling strategies (e.g., uniform, random), cost-effective measurements (e.g., incremental build of software configurations), and dimensionality reduction methods (e.g., transfer learning, feature selection, software debloating).
I will finally argue that deep variability is both the problem and solution of frictionless reproducibility, calling the software science community to develop new methods and tools to manage variability and foster reproducibility in software systems.
Exposé invité Journées Nationales du GDR GPL 2024
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
UCSF Informatics Day 2014 - Elizabeth St. Lezin, "Blood Transfusion Research using Electronic Databases: The NHLBI REDS-III Program"
1. BLOOD TRANSFUSION RESEARCH
USING ELECTRONIC DATABASES:
THE NHLBI REDS-III PROGRAM
Beth St. Lezin, MD
Ed Murphy, MD, MPH
Nareg Roubinian, MD
Brian Custer, MPH, PhD
Roberta Bruhn, MS, PhD
Anne Guiltinan, MA, LMFT
Ebi Fiebig, MD
Ashok Nambiar, MD
2. REDS: History and Acronyms
1989 2005 2011 2018
REDS REDS-II REDS-III
2006 – International Programs
REDS and REDS-II=
Retrovirus
Epidemiology
Donor
Study
REDS –III =
Recipient
Epidemiology and
Donor evaluation
Study
3. Domestic Program
Address scientific research priorities in blood banking
and transfusion medicine in the US
Continue research aimed at donor/donations and blood banking
issues
Start to address transfusion practice and recipient risk issues:
Evaluating blood product utilization practices in various clinical settings and
in specific patient populations and their associated outcomes and costs
Evaluating the risks of allogeneic blood transfusion and their determinants
on clinical outcomes
Evaluating the potential clinical benefit(s) of introducing a modified product
or treatment strategy
Characterization of the risks, benefits, and clinical outcomes of prophylactic
versus therapeutic transfusion strategies, and alternatives to allogeneic
transfusions
Education and training component
3
5. Domestic Program – Phase 2
Planned Phase 2 studies:
1. RBC Transfusion in the Elderly Transfusion
Outcomes (RETRO)
• 6 minute walk test and quality of life surveys
1. Severe Transfusion Reactions including Pulmonary
Edema (STRIPE)
• Active surveillance of tx reactions and a case-
control study of TACO
1. Genetic basis of differential RBC storage capacity
and iron balance and clinical syndromes in high
Intensity blood donors (RBC-Omics)
• GWAS of 14,000 donors characterized by
hemolysis of their stored RBCs and by their
donation intensity
5
7. REDS-III Database Approach
• Monthly downloads of type & cross and issued unit
data from hospital transfusion services
• Matching to clinical data from hospital medical
information system
• Identity coding by honest broker function and
uploading data to secure MyResearch website
• Download data to CCC and matching to
donor/donation database
• Formulation of three deliverable databases
8. UCSFMC
Apex EMR
VAMC
Vista EMR
THREDS
& CTSI ARS
VAMC
programmer
Clarity Tables
to IT
consultant
BCP
Blood Donor &
Blood Product
Data
UCSF/BSRI
REDS-III Hub
CTSI
MyResearch
Honest Broker
SFGH
EMR
Donation Components Recipient
Databases sent to
REDS-III Data Coordinating Center
REDS-III
Data Flow
10. Snap-shot of SFGH Pilot data
Recipient Gender Age Race Diagnosis Service Discharge
ID Diagnosis
2 Male 54 White
Anemia Chr
Disease Nec Medicine Longterm Care
End Stage Renal
Disease
Mental Health
Rehab.
Dead, Other Death, Autopsy
Performed
Atrial Fibrillation
Cachexia
Blood Unit ID Blood Transfusion Donation Donation
Component Date Number Date
W117009128332LRA RBC 11/12/2009 W117009128332005 10/31/2009
W117009133548LRA RBC 11/13/2009
W11700913354800
L 11/5/2009
Donor ID Sex Age Race Education Donor Procedure Donation
Type Type Type
65006037199
3 Male 17 Hispanic High School or less First Whole Blood Homologous
65006030417
7 Male 52 White Master's or Professional Degree Repeat Whole Blood Homologous
Patient Database
Components Database
Donor/
Donation
Database
11. Snap-shot of SFGH Pilot data
Patient Database Components Database Donor/Donation DatabaseRecipient Gender Age Race Diagnosis Service Discharge Blood Unit ID Blood Transfusion Donation Donation Donor ID Gender Age Race Education Donor Procedure
ID Status Component Date Number Date Type Type
SFGH001 Female 47 Black Acc Pois-Anticonvulsant FamilyMedicine Routine W117009130462LRA RBC 11/12/2009 W117009130462007 11/3/2009 650060305992 Female 38 White Some College/Tech.School First Whole Blood
End Stage Renal Disease Discharge Home
SFGH002 Male 54 White Anemia Chr Disease Nec Medicine Longterm Care W117009128332LRA RBC 11/12/2009 W117009128332005 10/31/2009 650060371993 Male 17 Hispanic High School or less First Whole Blood
End Stage Renal Disease Mental Health Rehab. Dead, Other Death, W117009133548LRA RBC 11/13/2009 W11700913354800L 11/5/2009 650060304177 Male 52 White Master's or Prof. Degree Repeat Whole Blood
Cachexia Autopsy Performed
SFGH003 Male 61 Black Luekocytopenia, Unspecified Lhh Acute Medical Longterm Care W117009135232LRA2 RBC 11/16/2009 W11700913523200T 11/2/2009 650060372232 Male 31 White Master's or Prof. Degree Repeat 2RBC
Open Wound Buttock-Comp Lhh Bed Hold Other Facility
R/O Hiv Disease Medicine Acute Care Facility
SFGH007 Male 61 Asian Ac Osteomyelitis-Ankle Trauma Active W117009224115LRA1 RBC 11/1/2009 W11700922411500N 10/10/2009 650060191503 Male 24 White High School or less Repeat 2RBC
Acute Renal Failure Nos Lhh SnfRehab Active
Chronic Kidney Disease, Stage V
SFGH008 Female 63 Asian Disorder Bone &Cart Nos Orthopedics Rehab Facility W117009339905LRA RBC 11/11/2009 W117009339905009 10/29/2009 650060263725 Female 19 White High School or less Repeat Whole Blood
Female Breast Ca Nos Lhh SnfRehab Routine
Knee Replacement Status Discharge Home
SFGH009 Male 50 Hispanic Ac RespiratoryFailure FamilyMedicine Rehab Facility W117009125577LRA RBC 11/8/2009 W11700912557700B 10/10/2009 650026346189 Male 35 Hispanic Bachelor's Degree Repeat Whole Blood
R/O Hiv Disease Lhh SnfRehab W117009224107LRA RBC 11/9/2009 W11700922410700N 10/10/2009 650060341853 Male 27 White High School or less Repeat Whole Blood
Sepsis
Buttock Cellulitis
SFGH010 Male 49 Asian Abn Rxn-Surgical Px Nec Urology Rehab Facility W117009124571LRA1 RBC 11/1/2009 W117009124571002 10/7/2009 650060255650 Male 29 Hispanic High School or less Repeat 2RBC
Abnormal Glucose Nec Longterm Care W117009337849LRA2 RBC 11/1/2009 W11700933784900P 10/7/2009 650060369524 Male 30 White Some College/Tech.School First 2RBC
Atrial Fibrillation W117009131270LRA RBC 11/2/2009 W117009131270007 10/28/2009 650060303614 Male 25 N/A High School or less Repeat Whole Blood
Acute Renal Failure Nos W117009130360LRA RBC 11/3/2009 W11700913036000J 11/1/2009 650060372043 Male 43 White Bachelor's Degree First Whole Blood
Cerebral Embol W Infarct W117009134580LRA RBC 11/3/2009 W117009134580005 11/1/2009 650060305952 Male 41 Asian Master's or Prof. Degree Repeat Whole Blood
W117009222936LRA2 RBC 11/4/2009 W11700922293600I 10/10/2009 650060267910 Male 37 White Some College/Tech.School Repeat 2RBC
W117009127098LRA1 RBC 11/5/2009 W117009127098009 10/13/2009 657000010800 Male 58 White Master's or Prof. Degree Repeat Apheresis
SFGH012 Male 66 Black Bronchus/Lung Ca Nec Neurology Acute Care Facility W117009133992LRA RBC 11/9/2009 W11700913399200I 11/7/2009 650060372892 Female 16 White High School or less First Whole Blood
Chr Blood Loss Anemia W117009135339LRA RBC 11/9/2009 W117009135339007 11/7/2009 650060372884 Female 28 White Bachelor's Degree First Whole Blood
SFGH014 Male 64 Hispanic Alc Dep Nec & Nos-Cont Medicine Routine W117009126916LRA RBC 11/7/2009 W11700912691600Q 10/8/2009 650060282969 Male 57 Asian Master's or Prof. Degree Repeat Whole Blood
Alcohol Liver Cirrhosis Discharge Home W117009128984LRA RBC 11/7/2009 W117009128984007 10/10/2009 650060071034 Female 53 White Master's or Prof. Degree Repeat Whole Blood
SFGH00022Female 67 Black Abn Rxn-Artificial Impl Orthopedics Routine W117009222880LRA1 RBC 11/3/2009 W11700922288000I 10/6/2009 650060369345 Male 16 White High School or less First 2RBC
Mechan.Compl.Of Int.Orth. Dev Discharge Home W117009338294LRA RBC 11/3/2009 W11700933829400A 10/6/2009 650060096234 Male 28 White Some College/Tech.School Repeat Whole Blood
12. IRB, HIPAA and Honest Broker
• UCSF CHR approval obtained with waiver of consent
• Data use agreement with VAMC; MOU with SFGH pending
• Use of UCSF CTSI MyResearch secure portal by the CCC to
maintain REDS-III data directories securely
UCSF CTSI offers “honest broker” service through its
MyResearch secure portal:
• Holds identified data and translation keys in secure escrow.
• Provides de-identified data to researchers.
• Provides de-identification and re-identification services for
researchers.
13. Possible Recipient database analyses
• Epidemiology of blood component transfusion:
• RBC, Platelets and Plasma – incidence, secular trends and outcomes
• Transfusion Reactions
• Compare active surveillance (clinical study) and passive reporting; estimate
degree of underreporting using changes in vital signs or post transfusion
interventions eg medications, chest xrays etc.
• Trauma
• Epidemiology of transfusions, outcomes, risk factors for poor outcomes.
• Neurosurgery and neurologic injury
• Identifying Predictors of Transfusion
• Extending Kaiser models to REDS-III recipient database for predicting
transfusion of red cells, platelets or plasma
14. Status Report
• First quarter 2013 data uploaded from UCSF-MC; VAMC and
SFGH uploads imminent pending admin approvals
• Backfill additional quarters of data into 2014
Conclusions
• REDS-III leverages the EMR to address important clinical
questions regarding the utilization and outcomes of blood
transfusion
• The work involved is not trivial, and demands close interaction
between programmers and content (medical) experts