Post Operative Care | PACU | Complications | Treatment Yashasvi Verma
Post operative period is the most crucial and
critical span of time after completion of surgery
In this period numerous complications occur and if not treated on time can prove fatal hence increasing the mortality rate .
The specialized care provided to the patient after completion of surgery till the patient is fully conscious
This specialized care is provided in a specialized area called PACU
SEVERAL POST OPERATIVE COMPLICATIONS LIKE
HYPOXIA , HYPERTENSION , HYPOTENTION , HYPO THERMIA , HYPERTHERMIA , MODIFIED ALDERT SCORE , PAIN ASSESMENT AND TREATMENT , POST OPERATIVE NAUSEA AND VOMITING , ETC. MIGHT OCCUR .
Post Operative Care | PACU | Complications | Treatment Yashasvi Verma
Post operative period is the most crucial and
critical span of time after completion of surgery
In this period numerous complications occur and if not treated on time can prove fatal hence increasing the mortality rate .
The specialized care provided to the patient after completion of surgery till the patient is fully conscious
This specialized care is provided in a specialized area called PACU
SEVERAL POST OPERATIVE COMPLICATIONS LIKE
HYPOXIA , HYPERTENSION , HYPOTENTION , HYPO THERMIA , HYPERTHERMIA , MODIFIED ALDERT SCORE , PAIN ASSESMENT AND TREATMENT , POST OPERATIVE NAUSEA AND VOMITING , ETC. MIGHT OCCUR .
Erector spinae plane block is a relatively novel approach to pain management for a variety of surgical procedures. ESP block is a challenging anesthesia and analgesia technique that needs more research.
Transport of critically ill patient in hospital is a great task and requires, a well trained team and if not carried out with precision can lead to life threatening accidents..
as the life expectancy has increased. more and more elderly patients are undergoing surgery. the burden of postoperative dysfunction has to be increased in future. There should be attempt to identify the risk factors and measures to prevent POCD.
Post anesthesia care unit or , High Dependency unit is part of hospital for Post surgery/procedures recovery.Nursing, anesthesiologist, surgeons, hospital administration need to know about ideal conditions.
Anaesthetic considerations for Robotic Surgery, What to expect, how to go ahead. An update and incite on the intricacies of Robotic Surgery and Anaesthetic implications.
Anaesthesia International Certificates FRCA, MCAI & EDAIC -OrientationSCORE Training Centre
Anesthesia International Certificates FRCA, MCAI & EDAIC -Orientation
Session surmise most of the reputable Postgraduate international certificates in the Anesthesia specialty. Which are:
FRCA, Fellowship of the Royal College of Anesthetists
MCAI, Membership of College of Anesthesia of Ireland.
EDAIC, European Diploma in Anesthesia and Intensive Care Medicine.
Erector spinae plane block is a relatively novel approach to pain management for a variety of surgical procedures. ESP block is a challenging anesthesia and analgesia technique that needs more research.
Transport of critically ill patient in hospital is a great task and requires, a well trained team and if not carried out with precision can lead to life threatening accidents..
as the life expectancy has increased. more and more elderly patients are undergoing surgery. the burden of postoperative dysfunction has to be increased in future. There should be attempt to identify the risk factors and measures to prevent POCD.
Post anesthesia care unit or , High Dependency unit is part of hospital for Post surgery/procedures recovery.Nursing, anesthesiologist, surgeons, hospital administration need to know about ideal conditions.
Anaesthetic considerations for Robotic Surgery, What to expect, how to go ahead. An update and incite on the intricacies of Robotic Surgery and Anaesthetic implications.
Anaesthesia International Certificates FRCA, MCAI & EDAIC -OrientationSCORE Training Centre
Anesthesia International Certificates FRCA, MCAI & EDAIC -Orientation
Session surmise most of the reputable Postgraduate international certificates in the Anesthesia specialty. Which are:
FRCA, Fellowship of the Royal College of Anesthetists
MCAI, Membership of College of Anesthesia of Ireland.
EDAIC, European Diploma in Anesthesia and Intensive Care Medicine.
IOSR Journal of Mathematics(IOSR-JM) is an open access international journal that provides rapid publication (within a month) of articles in all areas of mathemetics and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications in mathematics. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Assessment of the Implementation of Ventilator-associated Pneumonia Preventiv...IOSR Journals
Background: Pneumonia associated with mechanical ventilation (VAP) is one of the important
causes of nosocomial infections in pediatric intensive care units (PICU). VAP is the leading cause of morbidity
and mortality in PICUs. Aim: To assess the compliance to ventilator bundle components: elevation of the head
of bed >30, sedation interruption, spontaneous breathing trial, peptic ulcer prophylaxis and its effect on the
prevention of VAP. Subjects and Methods: A case control study at PICU of Abo EL Reish El Moneira Hospital,
including all mechanically ventilated patients admitted over a period of one year. The study tested the effect of
implementation of this bundle as regard the rate of VAP in both group, compliance to bundle and most affecting
component of it. Results: There was decrease incidence of VAP after implementation of the bundle, from (50%)
to (14%). Development of VAP was mostly affected by being in supine position, long duration of mechanical
ventilation and presence of pump failure. (p<0.05) The compliance to bundle components was statistically
significant, p= 0.001. Conclusion: VAP rate decreased after implementation of this bundle. Elevation of the
head of bed was the most compliant component of bundle in the PICU.
Journal Presentation on article Comparative efficacy of different combination...Shubham Jain
Journal Presentation on article Comparative efficacy of different combinations of acapella, active cycle of breathing technique, and external diaphragmatic pacing in perioperative patients with lung cancer
journal club and critical appraisal checklist
intensive recruitment versus moderate recruitment strategy in postop cardiac surgery patients to avaoid postop pulmonary complications
Laparoscopic Gynecologic Surgery Under Regional Neuraxial Anaesthesia: the be...semualkaira
At present, most laparoscopic
interventions are performed under general anesthesia. In literature
we have few retrospective studies, with few cases, that show just
minor laparoscopic proceduresperformed under regional anesthesia.
Laparoscopic Gynecologic Surgery Under Regional Neuraxial Anaesthesia: the be...semualkaira
At present, most laparoscopic
interventions are performed under general anesthesia. In literature
we have few retrospective studies, with few cases, that show just
minor laparoscopic proceduresperformed under regional anesthesia.
The effects of laryngeal mask airway versus endotracheal tube on atelectasis in patients undergoing general anesthesia assessed by lung ultrasound: A protocol for a prospective, randomized controlled trial
Prehospital rapid sequence intubation improves functional outcome for patient...Emergency Live
In adults with severe TBI, prehospital rapid sequence intubation by paramedics increases the rate of favorable neurologic outcome at 6 months compared with intubation in the hospital.
pediatric plastic anethesia cleft lip and palate.pptxmohamed abuelnaga
lecture about anaesthesia management for cleft lip and cleft palate surgery. what is the best anaesthesia technique .what is the best analgesic modality for perioperative pain control. how to perform trigeminal nerve block .role of acupuncture in management of postoperative
pain and agitation.
cerebral vasospasm carries a high risk of mortality and morbidity following aneurysmal SAh. the accurate mechanism of vasospasm is still not fully understood.
mechanism oriented management is the best way for disease management. several recent mechanisms of vasospasm as well as recent methods of management have developed.
new technique for pain management ,described by dr forero ,it can replace epidural anesthesia,paravertebral anesthesia and other regional blocks.it can be used for both acute and chronic painful conditions
different causes of low back pain,how to diagnose low back pain ,interventional management for low back pain ,evidence based interventions ,color real photos for different interventions
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
2. Early tracheostomy :
-may decrease the duration of mechanical
ventilation, sedation exposure, and intensive care
stay, possibly resulting in improved clinical
outcomes.
Late tracheostomy:
-may prevent early unnecessary tracheostomy
The evidence is conflicting
3.
4. in 1989, a Consensus Conference on Artificial
Airways in Patients Receiving Mechanical
Ventilation made the following guidelines :
1. For anticipated need of the artificial airway up
to 10 days, the translaryngeal route is preferred.
2. For anticipated need ofthe artificial airway for
greater than 21 days, tracheotomy is preferred.
5.
6.
7. These two independent
retrospective European postal
surveys showed that the timing
for performing tracheostomy is
not fully standardized in Europe
either.
8.
9. A retrospective analysis of 118 trauma patients
who underwent tracheostomy for airway and
pulmonary management was undertaken.
Timing of the procedure was defined as early (0-3
days), intermediate (4-7 days), and late > 7 days).
Our study suggests that early tracheostomy may
decrease pulmonary septic complications in
trauma patients.
Although no change in length of stay can be
attributed to the early performance of
tracheostomy, preventing pneumonia in the
intensive care unit setting with its resulting high
expense is beneficial.
10.
11. Results:
Rumbak et al reported that in patients
predicted to require mechanical ventilation
for 2 or more weeks, early (within the first 48
hours) tracheostomy had significantly less 30
day mortality rate, ventilator- associated
pneumonia, and accidental extubations, than
prolonged translaryngeal intubation (<14
days).
12.
13.
14.
15.
16. There is a growing volume of
published data that suggests that
relatively early tracheostomy (possibly
>7 days) may indeed decrease ICU
days, ventilator days, and/or
ventilator-associated pneumonia, all
outcomes that translate into a direct
patient benefit.
17.
18. Conclusion:
in mechanically ventilated adult ICU patients,
there was no statistically significant
difference in the rates of VAP with early
tracheotomy (after 6-8 days of laryngeal
intubation) versus late tracheotomy (after 13-
15 days of laryngeal intubation).
19.
20.
21. In this study , the medical records of patients
who underwent tracheostomy in the medical
ICU of a tertiary medical centre from July
1998 to June 2001 were reviewed.
22. Conclusion:
"In critically ill adult patients requiring prolonged mechanical
ventilation, tracheotomy performed at an early stage(within the first
week) may shorten the duration of artificial ventilation and length of
stay in intensive care "(level 1B)
23. The TracMan study , an open multi-centred randomised
clinical trial conducted between 2004 and 2011 involving 70
adult general and two cardiothoracic ICUs units in 13
university and 59 non-university hospitals, was carried out in
the United Kingdom to assess the impact of early (day 1-4 of
ICU admission) versus late (day 10 or later) tracheostomy.
The study included 909 patients randomised to early(n=455)
or late (n=454) tracheostomy.
24. Patient characteristics were similar across both groups, with
respiratory failure the most common cause of admission to
the ICU.
There was no significant difference in mortality between the
early and late tracheostomy groups at 30 days (139 versus 141
deaths) or at 2 years post randomisation, with a 74% follow up
rate.
There was also no significant difference in ICU or hospital
length of stay and no significant difference in antibiotic
use.
However, mean days of sedation were predictably reduced
to 6.6 days in the early group compared with 9.3 days in the
late group.
25. Systematic review and meta-analysis of randomized trials
Patients allocated to tracheostomy within 10 days of start of
mechanical ventilation was compared with placement of
tracheostomy after 10 days if still required
26. 4482 publications were identified and 14 trials
enrolling 2406 patients were included
Primary outcomes were mortality within 60 days, and
duration of mechanical ventilation, sedation, and
intensive care unit stay.
Secondary outcomes were the number of
tracheostomy procedures performed, and incidence
of VAP and mortality at longest follow-up.
27.
28.
29.
30.
31.
32.
33.
34. 1- as a meta-analysis our research is retrospective
and subject to the methodological soundness of
the individual studies.
2-We have tried to keep the probability of bias to
a minimum by developing a detailed protocol a
priori, carrying out a thorough search for published
and unpublished data, and using explicit criteria
for study selection, data collection, and data
analysis.
35. As a result, we consider that our robust
approach has resulted in recommendations
directly applicable to clinical practice.
Secondly, our review includes trials from
1976 to 2012. There has been an enormous
change in clinical practice during this
period, which could account for the
negative findings.
36. Thirdly, there is little guidance on the prediction of
prolonged mechanical ventilation and the timing of
tracheostomy insertion is based on this assessment.
Overall, all of the included studies have different
definitions of early tracheostomy and prolonged
mechanical ventilation.
Consequently, we can only provide data on the
safety and effectiveness of early tracheostomy on
reduction of mortality compared with standard
37. It is clear that continued research is needed to find
appropriate tools to predict the duration of mechanical
ventilation on the ICU.
Future research should be aimed at standardizing the
definitions of early tracheostomy and examining if it
would be beneficial in certain patient groups
The safety and late complication rates of tracheostomy
are poorly understood and further efforts should be
directed to examine the wider socio-economic
consequences of the procedure.
38. 1- early tracheostomy does not carry any
mortality advantage in the heterogeneous patient
population included in this work.
2- early tracheostomy does not help to reduce
length of ICU stay or incidence of VAP.
3-early tracheostomy leads to reduction in the
duration of sedative use when performing early
tracheostomy, although this is not accompanied
by a reduction in duration of mechanical
ventilation.
4-early tracheostomy leads to unnecessarily high
procedural rate with associated increased
morbidity and possibly financial cost.
39. 1-tracheostomy before Day 10 of mechanical
ventilation should be avoided.
2-Further research with adequately powered
and methodologically sound clinical trials
should address the questions if any particular
subgroups of critically ill patients would
benefit from the procedure and to
understand the longer term effects of the
intervention.
40.
41. In our own ICU, we usually perform tracheostomy as
soon as any of the following indications is met:
1. The specific diagnosis and clinical scenario clearly
suggest with reasonable certainty that the need for
mechanical ventilation will exceed 10 to 14 days
2. The patient has objectively proven by nerve
conduction studies and/or EMG, and by neurologic
examination, to have severe polyneuropathy and/or
myopathy with profound muscle weakness that
cannot be reasonably expected to recover in a few
days, or with moderate weakness only but the
patient has failed one weaning attempt.
42. 3. Any patient with thick secretions who has
already failed an attempt to extubate because of
those secretions or in whom the physician is
reluctant to attempt extubation because of a weak
cough and limited respiratory reserve.
4. Any patient with morbid obesity and known
severe sleep apnea who fails one weaning attempt
using Bi-PAP.
5. Any patient who fails 2 weaning attempts or has
a life threatening complication with the first failure,
ie, arrhythmias, angina, exceedingly difficult
reintubation, transient ischemic attack, etc.
43. 6. The patient has severe and irreversible
neurologic deficit that interferes with
breathing, for example, a high C-spine
transection and/or a neurologic event that
results in a profoundly impaired level of
consciousness such as a thalamic stroke.
7. Known upper airway obstruction caused by,
but not limited to, pharyngeal tumor with ball-
valve effect, fractured arytenoid cartilages, or
paralyzed vocal cords