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THE PROCESS OF CONCEPTION
OVA Released from the Graafian Follicle Will be surrounded by a ring of mucopolysaccharide fluid (Zonapellucida) and a circle of cells (Corona radiata) Zonapellucida and Corona Radiata protects the ova by serving as a buffer against injury Moves from the ovary to the fallopian tube through the cilia and peristaltic movement of fallopian tube
SPERM Per ejaculation, 2.5ml semen containing 50-200M spermatozoa is released (ave 400M sperm/ejaculation) Moves through the cervix, uterus, fallopian tube because of their flagella and uterine contractions Undergoes CAPACITATION (changes in the plasma membrane of the sperm head to reveal sperm binding receptor sites) before penetrating into the corona radiata
Sperm clusters around coronal cells Will release HYALURONIDASE (proteolytic enzyme) to dissolve the corona radiata Sperm penetrates the cell; cell membrane  of ova changes composition to become impenetrable to other sperm
Sperm and ova fuse carrying 23 pairs of chromosomes each If sperm carries X sex chromosome paired with the ovum X chromosome = female zygote If sperm carries Y sex chromosome paired with the ovum X chromosome = male zygote
IMPLANTATION Zygote move from fallopian tube to uterus It will undergo series of mitotic divisions resulting to a cleavage formation, 1 in every 22 hour, with the cleavage division happening 24 hours after fertilization Once it reaches the uterus, zygote is now composed of 32 -50 ball of cell termed as a MORULA
Another 3-4 days, morula becomes a BLASTOCYST consisting of: An inner cell mass which will become the future embryo Trophoblast which will become the placenta and membranes
At approx 8-10 days after fertilization, blastocyst attaches to the endometrium Sheds off last residues of corona radiata and zonapellucida Brushes against endometrium (apposition) and settles down A slight vaginal bleeding is experienced during implantation stage because capillaries are ruptured by the implanting trophoblast cells
EMBRYONIC & FETAL STRUCTURES DECIDUA – uterus that has grown thick and vascular 3 areas ,[object Object]
Deciduacapsularis – portion that stretches or encapsulates the surface of the trophoblast
Deciduavera – the remaining portion of the uterine lining,[object Object]
They begin the formation of the placenta
Consists of a central core of connective tissue and fetal capillaries,[object Object]
PLACENTA ,[object Object]
Has 25-30 cotyledons (placental compartments that lie on the maternal side)
Has 2 sides
Maternal – dirty rough
Fetal – shiny smooth,[object Object]
Secretes endocrine hormones (syncytial cells)
hCG – 1st placental hormone         - enusures corpus luteum to continuously produce progesterone and estrogen          - supresses maternal immunologic reaction so that placental tissue is not detected and rejected as a foreign substance
           - if fetus is male, stimulates the testes to begin producing testoterone           - at 8 week, begins progesterone production, as a result, CL disintegrates and hCG production decreases ,[object Object],          - contributes to mammary gland development of mother in preparation for lactation           - stimulates uterine growth to accommodate growing fetus
[object Object],           - necessary to maintain endometrial lining of the uterus during pregnancy            - reduces contractility of uterus during pregnancy preventing preterm labor ,[object Object],          - with both growth promoting and lactogenic (milk producing) properties           - promotes mammary gland (breast) growth in preparation for lactation

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The process of conception

  • 1. THE PROCESS OF CONCEPTION
  • 2. OVA Released from the Graafian Follicle Will be surrounded by a ring of mucopolysaccharide fluid (Zonapellucida) and a circle of cells (Corona radiata) Zonapellucida and Corona Radiata protects the ova by serving as a buffer against injury Moves from the ovary to the fallopian tube through the cilia and peristaltic movement of fallopian tube
  • 3. SPERM Per ejaculation, 2.5ml semen containing 50-200M spermatozoa is released (ave 400M sperm/ejaculation) Moves through the cervix, uterus, fallopian tube because of their flagella and uterine contractions Undergoes CAPACITATION (changes in the plasma membrane of the sperm head to reveal sperm binding receptor sites) before penetrating into the corona radiata
  • 4. Sperm clusters around coronal cells Will release HYALURONIDASE (proteolytic enzyme) to dissolve the corona radiata Sperm penetrates the cell; cell membrane of ova changes composition to become impenetrable to other sperm
  • 5. Sperm and ova fuse carrying 23 pairs of chromosomes each If sperm carries X sex chromosome paired with the ovum X chromosome = female zygote If sperm carries Y sex chromosome paired with the ovum X chromosome = male zygote
  • 6. IMPLANTATION Zygote move from fallopian tube to uterus It will undergo series of mitotic divisions resulting to a cleavage formation, 1 in every 22 hour, with the cleavage division happening 24 hours after fertilization Once it reaches the uterus, zygote is now composed of 32 -50 ball of cell termed as a MORULA
  • 7. Another 3-4 days, morula becomes a BLASTOCYST consisting of: An inner cell mass which will become the future embryo Trophoblast which will become the placenta and membranes
  • 8. At approx 8-10 days after fertilization, blastocyst attaches to the endometrium Sheds off last residues of corona radiata and zonapellucida Brushes against endometrium (apposition) and settles down A slight vaginal bleeding is experienced during implantation stage because capillaries are ruptured by the implanting trophoblast cells
  • 9.
  • 10. Deciduacapsularis – portion that stretches or encapsulates the surface of the trophoblast
  • 11.
  • 12. They begin the formation of the placenta
  • 13.
  • 14.
  • 15. Has 25-30 cotyledons (placental compartments that lie on the maternal side)
  • 18.
  • 19. Secretes endocrine hormones (syncytial cells)
  • 20. hCG – 1st placental hormone - enusures corpus luteum to continuously produce progesterone and estrogen - supresses maternal immunologic reaction so that placental tissue is not detected and rejected as a foreign substance
  • 21.
  • 22.
  • 23.
  • 25.
  • 26. Protects fetus from temperature change
  • 27. Aids in muscular development because it allows fetus’ freedom to move
  • 28.
  • 29.
  • 30. Amniotic membrane – 2nd membrane lining the chorionic membrane; forms beneath the chorion - produces amniotic fluid - produces phospholipid that initiates the formation of prostaglandins which can cause uterine contractions and may be the trigger that initiates labor
  • 31.
  • 32. 53cm (21 in) length; 2 cm thick
  • 33. Wharton’s jelly – a gelatinous mucopolysaccharide that forms the bulk of the umbilical cord giving it its body; prevents pressure on the veins and arteries
  • 34. Outer surface is covered with amniotic membrane
  • 35.
  • 36. Walls are with smooth muscles, no nerve supply
  • 38.