The kidney is an organ that filters waste from the blood and regulates fluid balance. It contains an outer cortex and inner medulla. Blood enters via the renal artery and leaves via the renal vein after being filtered through nephrons. Urine is drained from the kidney through the ureter into the bladder. Kidney functions include filtering waste, regulating minerals and producing hormones. Kidney diseases can be acute or chronic and cause injury or failure requiring dialysis or transplant. Kidney stones form from minerals in the urine.