This PhD thesis presents methods for improving e-business design through business model analysis. The thesis addresses three research questions: how to design business models considering goal models, business collaborations, and e-services. It develops artifacts including a method for designing goal-aligned business models using means templates and transformation rules, a method for business model design based on analyzing business transaction types and resource identification, and a method for e-service design based on transforming business models. The contributions are methods for business model and e-service design that integrate intentions, objectives and stages of business interactions.