This document describes a serious game called Operation ARIES that teaches scientific inquiry skills through an interactive story. The game covers important concepts in psychology, sociology, biology, and chemistry. Players help the Federal Bureau of Science investigate flawed alien research by reading interactive texts, evaluating case studies, and interrogating research examples. It aims to help high school, college students, and adults learn to critically evaluate research claims. The game implements eLearning principles and dialogue to provide feedback and assess knowledge gained over its estimated 7-15 hours of gameplay.