The brain is the center of the nervous system located in the head and protected by the skull. It contains billions of neurons that communicate through long fibers called axons. While protected, the human brain is susceptible to damage from head injuries, strokes, diseases, and disorders. The cerebral cortex is divided into left and right hemispheres, each with four lobes - frontal, parietal, occipital, and temporal. Each hemisphere primarily interacts with the opposite side of the body through crossed connections in the brain and spinal cord.