This document discusses syrup as a liquid oral dosage form. Syrup is a viscous, concentrated solution of sucrose or other sugars that may contain flavorings and medicinal agents. Key components include sucrose or substitutes like sorbitol and glycerine. Syrups are colored using agents like mint, chocolate or amaranth. Proper storage at stable temperatures is important to prevent issues like inversion of sucrose or microbial growth. Examples provided of common medicated syrups include Demerol syrup and Phenergan syrup. The document covers syrup components, coloring, disadvantages, caramelization, containers and proper storage.

1. PRESENTED BY:
L.GOPI B.Pharm.,
AADHI BHAGAWAN COLLEGE OF PHARMACY
RANTHAM
GUIDED BY:
K.Shyamala M.Pharm.,
PROF OF DEPARTMENT OF PHARMACEUTICS
AADHI BHAGAWAN COLLEGE OF PHARMACY
RANTHAM

2. SYRUP
It’s a liquid dosage form taken to the oral route.
Viscous , concentrated solution of sucrose and
other sugars.
With ( or ) with out medicaments.
Flavouring agent vehicle.
Contain up to 85% to resist bacterial growth.
Intended for oral use.

3. COMPONENTS
Sucrose ( or ) other substitute ( glycogenic
or non-glycogenic )
Glycogenic = sorbitol , glycerine , propyl
glycol.
Non – glycogenic = methyl cellulose ,
Hydroxy methyl cellulose ( suitable for
diapetic partients )

4. COLOURING AGENTS
 Green = Mint
 Brown = Chocolate
 Red = Amaranth

7. DISADVANDAGES :
• Formation of invert sugar.
• Effect the taste , stability.
• glucose + fructose
sucrose
hydrolysis heat
invert sugar form

8. CARAMELIZATION :
• The product become black color is sucrose is over heat is called as
caramelization.
• The process avoid maintain temperature.
sugar = 110˚C
galatose = 160˚C
glucose = 160˚C
maltose = 180˚C
saccharose = 160˚C

14. MEDICATED SYRUP CONTAINING A
THERAPEUTIC AGENTS
1. Demerol syrup
2. Thorazine syrup
3. Phenergan syrup
4. Lithium citrate syrup
5. Gualfenesin syrup
6. Lpecal syrup

16. Example for other syrup image:

17. CONTAINERS

18. TYPES OF CONTAINERS :
1. Plastic container = colorless , brown color container mostly use
other color is available
2. Glass container = colorless , brown color form

19. TYPES OF CORKS :

20. STORAGE:
 It’s maintain the temperature.
 stable temperature.
 completely fill the container .
 no more air phase in surface of
product growth of micro organism.
 so completely fill the container

21.  so not completely fill the container to form microbial
organism growth.

25. THANK YOU

26. PREPARED BY :
L.GOPI B.Pharm., THIRD YEAR
CREATER 6 PHARMA GROUP
2012 – 2016
ABCP