Sumukti syrup Introduction Ingredients Raspanchaka Sumukti Syp. As a whole Doses and Anupana Research works done

1. SUMUKTI SYRUP
PRESENTED BY
DR PRABHAKAR MANU
2ND YEAR PG SCHOLAR
DEPT. OF MANASA ROGA
SDM COLLEGE OF AYURVEDA & HOSPITAL,
HASSAN

2. CONTENTS
• INTRODUCTION
• INGREDIENTS
• RASPANCHAKA
• SUMUKTI SYP. AS A WHOLE
• DOSES AND ANUPANA
• RESEARCH WORKS DONE

3. INTRODUCTION
•Popular & Anubhoota Yoga
of SDMCAH, Hassan
•Hepatoprotective in action
•Widely used in De-addiction
program

4. INGREDIENTS
1. Guduchi
2. Bringaraja
3. Kirata Tiktha
4. Amalaki
5. Hareetaki
6. Vibhitaki
7. Draksha
8. Sugar
9. Mandukaparni
10.Aswagandha
11.Yashtimadhu
12.Katuki

5. Sl
No
Sanskrit
name
Latin Name Part Used Quantity in
gms
1. Aswangandha Withania
somnifera
Root 400
2. Hareetaki Terminalia
chebula
Fruit 400
3. Vibhitaki Terminalia
bellerica
Fruit 400
4. Amalaki Emblica
offinalis
Fruit 400
5. Yashtimadhu Glycyrrihiza
glabra
Stem, Root 400

6. 6. Mandukaparni
Centrella
asiatica
W P 100
7. Guduchi Tinospora
cordifolia
Stem 400
8. Kiratatikhta Swertia
chirata
W P 800
9. Katuki Pichrorhiza
kurroa
Rhi 800
10
.
Draksha Vitis
venefera
Fruit 3200
11
.
Bringaraja Weddalia
calendulaca
W P 400

7. 15 Sodium
benzoate
.5%
16 sugar 50kg

8. Sl
No
Sanskrit name Ra Gu Vip Vee
1. Aswangandha Ti, Kas La M S
2. Hareetaki M,A,Kat,Kas,Ti La, Ru M U
3. Vibhitaki Kas La, Ru M U
4. Amalaki M,A,Kat,Kas,Ti La, Ru M S
5. Yashtimadhu M G, Sn M S
6. Mandukaparni M,Kat,Kas,Ti La, Sa M S
7. Guduchi Ti, Kas La M U
8. Kiratatikhta T La, Ru K S
9. Katuki Kat,T La K U
10. Draksha M, Kas G, Sn M S
11. Bringaraja Kat,T Ru, Ti K U

9. Sanskrit
name
KARMA
Aswangandha Rasayana, Vatakaphahara, Balya
Hareetaki Deepana,Tridoshahara, Rasayana
Vibhitaki Kaphapittahara, Bhedaka, Krimihara
Amalaki Rasayana, Tridoshahara,
Cakushya,Raktaprasadana
Yashtimadhu Balya, Rakthaprasadana, VP hara
Mandukaparni Balya,Vishahara,Medhya,Rasayana
Guduchi Deepana, Rasayana,VPK, Rakthashodaka
Kiratatikta Rakthashodhaka, KP hara
Katuki Pittahara, Deepana, Hrudya
Draksha Bruhmana, VP hara, Vrushya

10. SUMUKTI SYP. AS A
WHOLE
• Rasa- Tiktha, Kashaya
• Guna- Laghu, Ruksha
• Vipaka- Madhura
• Veerya- Sita
• Karma- Tridosha, Balya, Rasayana,
Vishagna, Rakthaprasadana,
Rakthashodaka, Medhya

11. DOSE
• 2 – 4 teaspoon twice a day after food
• Anupana - water

12. RESEARCH WORKS DONE
• A CLINICAL STUDY ON THE EFFICACY OF “SUMUKTI”-AN
INDEGINOUS COMPOUND ON MADATYAYA W.S.R TO
ALCOHOL DEPENDENCE
By
Dr. UNNIKRISHNAN P. M
Under The Guidance of
DR. SAVITHA H.P, MD(Ayu)
Associate Professor
Department of Manasa Roga

13. •Effect on subjective parameters
•Effect of sumukti on craving:
•30 patients shown craving in a mean of 8.13
which is reduced to 2.96 after treatment and
63.59% of improvement
•Effect of sumukti on tolerance:
•Mean score of tolerance was 6.36 before
treatment which came down to 1.36 after
treatment. It shown 78.61% of improvement

14. •Effect of sumukti on salience:
•Symptom salience had a mean score of 6.13
before treatment and it came down to 2.16
after treatment. It shown 64.76% of
improvement
•Effect of sumukti on loss of control:
•6.70 was the mean score of symptom loss of
control before treatment which came down
to 1.9 after completion of one month
treatment.

15. •Effect on objective parameters
•Effect of sumukti on liver function test
•Effect on total bilirubin:
•Before treatment means score of total
bilirubin was 1.35 which came down to 0.94
with 30.37% of improvement.
•Effect on direct bilirubin:
•Before treatment mean score of direct
bilirubin was 0.85 which came down to 0.58
with 31.76% of improvement.

16. •Effect on indirect bilirubin:
•Before treatment mean score of indirect
bilirubin was 0.50 which came down to 0.36
with 28% of improvement.
•Effect on aspartate aminotransferase [
SGOT]:
•Before treatment mean score of SGOT was
89.95 which came down to 30.06 with
66.58% of improvement.

17. • Effect of sumukti on persistent use:
• Persistent use showed a mean score of 7.13
before treatment and it came down to 1.73 after
completion of treatment. It showed 75.73% of
improvement
• Effect of sumukti on withdrawal symptoms:
• In withdrawal symptoms 5.2 was the mean score
before treatment which came down to 1.26 after
treatment. It showed 75.76% improvement

18. • Effect on alanine aminotransferase [SGPT]:
• Before treatment mean score of SGPT was 74.74
which came down to 27.01 with 63.86% of
improvement.
• Effect on USG abdomen:
• Mean value of USG abdomen was 1.33 before
treatment and it came down to 0.00 after
treatment.

19. ACTIVE INGREDIENTS
• Comparative study of the antioxidant and reactive
oxygen species scavenging properties in the extracts
of the fruits of Terminalia chebula, Terminalia
belerica and Emblica officinalis
• T. chebula, T. belerica and E. officinalis fruits,
through their measurement of activities in
scavenging of different free radicals including
hydroxyl, superoxide, nitric oxide, hydrogen
peroxide, peroxynitrite, singlet oxygen,
hypochlorous acid, phenol, flavonoid and ascorbic
acid content and total antioxidant activity

20. • Risk and safety assessment on the
consumption of Licorice root (Glycyrrhiza sp.),
its extract and powder as a food ingredient,
with emphasis on the pharmacology and
toxicology of glycyrrhizin
• Other in vivo and clinical studies have
reported beneficial effects of both licorice and
glycyrrhizin consumption including anti-ulcer,
anti-viral, and hepatoprotective responses.
• Tinosporia cordifolia has hepato protective
activity,And has antioxident activity.

21. POTENT HERBAL HEPATOPROTECTIVE DRUGS-
A REVIEW
SWERTIA CHIRATA
Amarogentin, Gentiopicrin ,Gentianine, Drug also
possesses digestive, hepatic (conditions pertaining to
the liver), tonic, astringent and appetizer properties
and used in cough, dropsy and skin diseases.
Eclipta Alba (Bhringaraj)- The hepatoprotective effect
of the ethanol/water (1:1) extract of Eclipta Alba
(Asteraceae) was studied at subcellular levels in rats
against (CCl4) -induced hepatotoxicity. The loss of
hepatic lysomal acid phosphatase and alkaline
phosphatase by (CCl4) was significantly restored by
Eclipta Alba.

22. • Picrorhiza kurroa (Kutki)
• The increased levels of serum glutamate
oxaloacetate transaminase (GOT), glutamate
pyruvate transaminase (GPT), alkaline
phosphatase, lipoprotein-X (LP-X) and bilirubin
in the infected animals were marked reduced
by different doses of picroliv.

23. DISPENSARY PACKAGING

24. Discussion and conclusion
• One of the important yoga acting as
Hepatoprotective action
• All ingredients have tikta rasa converted into
syrup base with added sugar to avoid patient
compliance and to make more palatable
• Majority of ingredients have antioxidant activity

25. Thank you……….