The document outlines four teaching formats for educating learners about newborn screening:
1. Point of Care (~5 min) - Provides resources for learners to access at the time of patient care to advance their knowledge. Suggested resources include fact sheets and overviews available online.
2. Morning Report (~20 min) - Informal case-based discussion led by faculty that presents major points about newborn screening using online teaching cases.
3. Noon Conference (~1 hr) - Formal lecture-style presentation that could feature a speaker from the state's newborn screening program.
4. Self-Directed Learning - Material for independent study including a video on newborn screening and the
A risk indicator can be any metric used to identify your risk exposure over time. It becomes a KRI when it tracks an important risk, or does so especially well because of its predictive value.
Dr Andrianov, CEO Cyntegrity, discusses the importance of keeping KRIs simple, the link to specific risks, and the emerging common industry KRIs.
A full recording of this webinar is available to MCC members: https://metricschampion.org/
How Researchers Can Get Science Done Faster Using an R&D Services MarketplaceSC CTSI at USC and CHLA
Date: Feb 6, 2019
Topic: How Researchers Can Get Science Done Faster Using an R&D Services Marketplace
Speaker: Dr. Zev Wisotsky is a Senior Scientist and R&D Specialist at Science Exchange, where he assists researchers in connecting with the right R&D providers for their experiments and alerts his clients to newly available technologies. Dr. Wisotsky earned his PhD in neuroscience investigating taste detection using fruit fly and mosquito models at UC Riverside. He then completed postdoctoral research at Stanford studying the role of brain regions involved in fear memory and addiction through optogenetic silencing of different brain circuits.
Overview: Science Exchange is an open marketplace for scientific research that breaks down barriers to collaboration and innovation. The platform makes it easy for researchers to access more than 6,000 services from a network of over 2,500 qualified research providers. In this webinar, you will learn how researchers can use Science Exchange to access new technologies, get competitive quotes for specific projects, and order from any service provider under a single, pre-established contract. The presentation will also include examples of successful projects and collaborations, initiated on the Science Exchange platform, that have accelerated breakthrough
Basic Study Recruitment and Regulatory Issues: Which Methods are Appropriate?CTSI at UCSF
Presentation by Laurie Herraiz, RD, CCRP in May 2012 at CHR sponsored workshop on UCSF Campus. Topics include, basics of regulatory and recruitment, iMedrRIS application instructions, waivers of consent/authorization for recruitment purposes, examples of approved recruitment materials, and common challenges to recruitment.
A risk indicator can be any metric used to identify your risk exposure over time. It becomes a KRI when it tracks an important risk, or does so especially well because of its predictive value.
Dr Andrianov, CEO Cyntegrity, discusses the importance of keeping KRIs simple, the link to specific risks, and the emerging common industry KRIs.
A full recording of this webinar is available to MCC members: https://metricschampion.org/
How Researchers Can Get Science Done Faster Using an R&D Services MarketplaceSC CTSI at USC and CHLA
Date: Feb 6, 2019
Topic: How Researchers Can Get Science Done Faster Using an R&D Services Marketplace
Speaker: Dr. Zev Wisotsky is a Senior Scientist and R&D Specialist at Science Exchange, where he assists researchers in connecting with the right R&D providers for their experiments and alerts his clients to newly available technologies. Dr. Wisotsky earned his PhD in neuroscience investigating taste detection using fruit fly and mosquito models at UC Riverside. He then completed postdoctoral research at Stanford studying the role of brain regions involved in fear memory and addiction through optogenetic silencing of different brain circuits.
Overview: Science Exchange is an open marketplace for scientific research that breaks down barriers to collaboration and innovation. The platform makes it easy for researchers to access more than 6,000 services from a network of over 2,500 qualified research providers. In this webinar, you will learn how researchers can use Science Exchange to access new technologies, get competitive quotes for specific projects, and order from any service provider under a single, pre-established contract. The presentation will also include examples of successful projects and collaborations, initiated on the Science Exchange platform, that have accelerated breakthrough
Basic Study Recruitment and Regulatory Issues: Which Methods are Appropriate?CTSI at UCSF
Presentation by Laurie Herraiz, RD, CCRP in May 2012 at CHR sponsored workshop on UCSF Campus. Topics include, basics of regulatory and recruitment, iMedrRIS application instructions, waivers of consent/authorization for recruitment purposes, examples of approved recruitment materials, and common challenges to recruitment.
Patients Recruitment Forecast in Clinical TrialsCognizant
Inaccurate patient recruitment forecasts for clinical trials cost pharmaceuticals and medical device manufacturers a huge amount of resources each year. We offer descriptions and examples of applying stochastic and non-stochastic approaches to increase accuracy in this crucial stage of drug testing.
Digital Scholar Webinar: Clinicaltrials.gov Registration and Reporting DocumentsSC CTSI at USC and CHLA
This 60-minute webinar covers the basic requirements for registration and results reporting requirements in Clinicaltrials.gov. Tips and tricks will be provided, as well as the most common issues to avoid to ensure a smooth and efficient process for public posting and updates to clinical studies. Learning Objectives At the conclusion of this webinar, participants will be able to identify internal contacts and resources available to assist with their Clinicaltrials.gov registration or results reporting.
Mosio's Clinical Trial Patient Recruitment and Retention Ebook (First Edition)Mosio
The first edition of Mosio's patient recruitment and retention ebook contains 68 tips and examples from clinical research industry professionals on ways to improve efforts to recruit, retain and engage clinical trial patients.
To get access to a free download of the 2nd Edition, visit http://www.mosio.com/prebook
For more information on how you can improve patient engagement while increasing workflow efficiencies in communicating with study participants using two-way text messaging, please visit us at http://www.mosio.com
Sustain and Build a Quality Culture in Today's RealitiesAjaz Hussain
What is quality, what is culture? Culture, quality, and assurance are just a few of the many abstract words in our lexicon. The meaning we make evolves with our development and maturity. Our education and training are necessary but insufficient for our development and maturity. Learning from experience is essential, and experiential learning is highly variable. Some continue to develop, but at different rates; others do not. In this presentation, I share why and how a connect-the-dots framework was developed and what it offers to individuals and organizations. Building refers to a process by which a source code guides software coding programs for a stand-alone computer or an enterprise-wide system. The context of this presentation is experiential. The content is derived from experiencing the real world via an intentional journey beginning in 2015 across the globe; since 2020, this journey has been searching for the source code to what is good. In my imagination and thought experiments, the building is a process, as in the context of software development. Coding for a stand-alone computer is similar but not interchangeable or automatically substitutable for writing and executing a personal or individualized continuous professional development plan. I speak about quality culture to ease the process of continuous learning, development, and maturity in professionals and management systems. To improve feedback and encourage backpropagation of errors of omission and commission to learn how to prevent mistakes and improve continually, I remind that it is increasingly relevant today to begin asking - how might we assess suitability, capability, and comparability of humans and AI in the context of CGMP compliance and maturity of a pQMS. I implicitly use the lexicon of biosimilars, interchangeable biosimilar products, and automatic generic substitution for brand products to help us make sense of our suitability and capability to know the difference in the maturity stages we call professional and good practitioners to appreciate the differences in the regulatory and social expectation of validation and assurance broadly and specifically as in the validation of computer and pharmaceutical systems.
Using alternative scholarly metrics to showcase the impact of your research: ...SC CTSI at USC and CHLA
Date: Feb 7, 2018
Speaker: Caroline Muglia, Co-Associate Dean for Collections and Technical Services; and Head, Resource Sharing and Collection Assessment, USC Libraries
Overview: Scholarship is increasingly being created, disseminated, and measured on digital and social platforms. If Twitter exchanges, Facebook “saves,” and YouTube hits are the new metrics for tracking scholarship, how are we measuring societal and educational impact and outreach? How can researchers display their research impact using social media on promotion and tenure dossiers? This webinar will discuss altmetrics, alternative scholarly metrics that measure the impact and use of scholarship. We will focus on PlumX, the tool used at USC, which combines traditional and new metrics to paint a comprehensive portrait of your scholarly output and its reach in various communities and with different stakeholders.
Tricks of the Trade: Patient Recruitment & Retention for Different Study TypesImperial CRS
In efforts to raise the bar for medical advancement, clinical trials are growing increasingly complex. This complexity, more often than not, leads to costly delays in enrollment. In this ebook, we'll take a look at 4 case studies for different study types, and examine the unique factors to consider during planning.
Best strategies for successful recruitment and retentionTrialJoin
Best strategies for successful recruitment and retention for clinical research studies
Contact info@trialjoin.com for more information about patient recruitment help, obtaining new studies or help with site management.
Patients Recruitment Forecast in Clinical TrialsCognizant
Inaccurate patient recruitment forecasts for clinical trials cost pharmaceuticals and medical device manufacturers a huge amount of resources each year. We offer descriptions and examples of applying stochastic and non-stochastic approaches to increase accuracy in this crucial stage of drug testing.
Digital Scholar Webinar: Clinicaltrials.gov Registration and Reporting DocumentsSC CTSI at USC and CHLA
This 60-minute webinar covers the basic requirements for registration and results reporting requirements in Clinicaltrials.gov. Tips and tricks will be provided, as well as the most common issues to avoid to ensure a smooth and efficient process for public posting and updates to clinical studies. Learning Objectives At the conclusion of this webinar, participants will be able to identify internal contacts and resources available to assist with their Clinicaltrials.gov registration or results reporting.
Mosio's Clinical Trial Patient Recruitment and Retention Ebook (First Edition)Mosio
The first edition of Mosio's patient recruitment and retention ebook contains 68 tips and examples from clinical research industry professionals on ways to improve efforts to recruit, retain and engage clinical trial patients.
To get access to a free download of the 2nd Edition, visit http://www.mosio.com/prebook
For more information on how you can improve patient engagement while increasing workflow efficiencies in communicating with study participants using two-way text messaging, please visit us at http://www.mosio.com
Sustain and Build a Quality Culture in Today's RealitiesAjaz Hussain
What is quality, what is culture? Culture, quality, and assurance are just a few of the many abstract words in our lexicon. The meaning we make evolves with our development and maturity. Our education and training are necessary but insufficient for our development and maturity. Learning from experience is essential, and experiential learning is highly variable. Some continue to develop, but at different rates; others do not. In this presentation, I share why and how a connect-the-dots framework was developed and what it offers to individuals and organizations. Building refers to a process by which a source code guides software coding programs for a stand-alone computer or an enterprise-wide system. The context of this presentation is experiential. The content is derived from experiencing the real world via an intentional journey beginning in 2015 across the globe; since 2020, this journey has been searching for the source code to what is good. In my imagination and thought experiments, the building is a process, as in the context of software development. Coding for a stand-alone computer is similar but not interchangeable or automatically substitutable for writing and executing a personal or individualized continuous professional development plan. I speak about quality culture to ease the process of continuous learning, development, and maturity in professionals and management systems. To improve feedback and encourage backpropagation of errors of omission and commission to learn how to prevent mistakes and improve continually, I remind that it is increasingly relevant today to begin asking - how might we assess suitability, capability, and comparability of humans and AI in the context of CGMP compliance and maturity of a pQMS. I implicitly use the lexicon of biosimilars, interchangeable biosimilar products, and automatic generic substitution for brand products to help us make sense of our suitability and capability to know the difference in the maturity stages we call professional and good practitioners to appreciate the differences in the regulatory and social expectation of validation and assurance broadly and specifically as in the validation of computer and pharmaceutical systems.
Using alternative scholarly metrics to showcase the impact of your research: ...SC CTSI at USC and CHLA
Date: Feb 7, 2018
Speaker: Caroline Muglia, Co-Associate Dean for Collections and Technical Services; and Head, Resource Sharing and Collection Assessment, USC Libraries
Overview: Scholarship is increasingly being created, disseminated, and measured on digital and social platforms. If Twitter exchanges, Facebook “saves,” and YouTube hits are the new metrics for tracking scholarship, how are we measuring societal and educational impact and outreach? How can researchers display their research impact using social media on promotion and tenure dossiers? This webinar will discuss altmetrics, alternative scholarly metrics that measure the impact and use of scholarship. We will focus on PlumX, the tool used at USC, which combines traditional and new metrics to paint a comprehensive portrait of your scholarly output and its reach in various communities and with different stakeholders.
Tricks of the Trade: Patient Recruitment & Retention for Different Study TypesImperial CRS
In efforts to raise the bar for medical advancement, clinical trials are growing increasingly complex. This complexity, more often than not, leads to costly delays in enrollment. In this ebook, we'll take a look at 4 case studies for different study types, and examine the unique factors to consider during planning.
Best strategies for successful recruitment and retentionTrialJoin
Best strategies for successful recruitment and retention for clinical research studies
Contact info@trialjoin.com for more information about patient recruitment help, obtaining new studies or help with site management.
Strategic IT Planning Your 3-Step ProcessIntroductionStrateg.docxrjoseph5
Strategic IT Planning: Your 3-Step Process
Introduction
Strategic IT Planning is required to ensure your resources and assets continue providing the results and the support your organization needs.
What is a Strategic Plan?
It is a roadmap to achieving a goal. It may cover your entire department or responsibility or it may focus on a specific issue or element of your role. It can be long and involved or a simply one-page document that provides guidance and steps you need to implement to achieve a goal.
Making it Happen
There are a few things that are important to your success. While it may seem that developing the Strategic Plan is the hardest part, most plans fail because of the implementation. The key is to keep it small and be successful, then build on that success for the next initiative. Don’t bite off too much or try to be too ambitious.
• Take your time and keep it manageable
• Link your plan to your company’s strategy
• Justify your initiative and get buy-in and support
• Don’t re-invent, rebuild
• Go slow, manage change
• Set aside time from your operational responsibilities to make it happen
Without a Strategic Plan, you and your team won’t be effective and you won’t be able to get results, get attention and get ahead.
Why you need an IT Strategy:
Redirect from tasks to opportunities and result
· Switch from fighting fires to preventing fires
· Reduce risk with planning and a longer view
Most Strategic Plans never get written or they fail because they are too involved and complex. Keep them simple and use these three basic steps as your core approach. Ask yourself these questions:
1. Why do you need to do it? What is your goal?
2. What are the things you need to get done to achieve your goal?
3. How can you make those things happen?
By following the 3 steps above and writing them down, you will have the outline of your Strategic IT Plan. Then, you establish the tactical things that will help you implement your plan.
Implementation Plan
Once you have established your strategic plan using the 3-step process, you need to develop your implementation plan. This includes getting approval and resources as well as the steps you need to take to achieve your strategic objective.
1. Set the objective for each step
2. Analyze internal/external factors
3. Develop solutions
4. Identify and eliminate barriers
5. Allocate resources (people, time, money)
6. Develop detailed tasks
7. Implement your plan!
Step Implementation
What Are The Roadblocks?
How Can You Overcome The Roadblocks?
What Resources Do You Need?
What Are The Timelines?
What Are The Main Steps To Implement Your Plan?
Parental Acceptance of a Mandatory Human
Papillomavirus (HPV) Vaccination Program
Daron Ferris, MD, Leslie Horn, BS, and Jennifer L. Waller, PhD
Objectives: The objective of this study was to determine factors that influence parent’s acceptance of a
mandatory school-based human papillomavirus (HPV) vaccination program.
Methods: A convenience sample of 325.
Ques-1 Prenatal diagnosis has both positive and potentially negativ.pdfapleathers
Ques-1: Prenatal diagnosis has both positive and potentially negative consequences. While it is
most often used to detect serious problems with the fetus, the technology can also be used
potentially to select embryos based on sex, appearance, Where do you think we should draw the
line in allowing parents to use prenatal diagnosis
Answer:
Genetic testing is performed for prenatal diagnosis to know any chromosomal or genetical -
inherited abnormalities of implanted human embryo. It has positive consequence, as some
couples would like to avoid getting a baby with genetic abnormalities. However, there are
negative consequences such as various \"ethical and moral issues of prenatal diagnosis as
explained below. Therefore, it is crucial to draw a line when conducting prenatal diagnosis
finally a couple musty get legal permissions to undergo prenatal diagnosis.
Screening tests for genetic issues can be performed in the first trimester, second trimester or both
trimesters. Carrier testing is also an option performed prior to or during pregnancy. Carrier
testing provides information as to whether one or both parents are carriers for certain inherited
disorders. The results of these tests are used to determine an appropriate plan of care for the
patient. Genetic testing of the fetus and the parents offers both opportunities and ethical
challenges. As a Registered Nurse, you need to be aware of your own feelings in order to provide
non-biased professional support.
Implications of genetic testing:
Genetic testing is the pre-implantation technology is now currently using in detecting and
screening embryo in order to assess whether the resultant embryos from fertilization are normal
or abnormal genotypically. A registered nurse must advice & support to a couple seeking
guidance about the genetic testing because genetic screening has various ethical and moral
aspects. The major rising ethical challenge is the connection between the pre-selection of
embryos based on meticulous genetic analysis followed by rising discrimination of disabled
people. This ethical problem is associated with selection of future children based on their low
levels of disabilities and abnormalities.
Ethical challenges with preimplantation of genetic testing or diagnosis (PGD):
1. PGD allows embryo selection after pregnancy or even before initiation of pregnancy.
However, this procedure is very controversial and faces a variety of moral ethics that are
completely relies upon moral status of embryo and prenatal diagnosis in selecting progeny
without the use of abortion (medical issue).
2. The major rising ethical challenge is the connection between the pre-selection of embryos
based on meticulous genetic analysis followed by rising discrimination of disabled people, a
psychological moral issue. This ethical problem is associated with selection of future children
based on their low levels of disabilities and abnormalities. A clinic should have license primarily
to perform preimplantatio.
Newborn Screening | Infant Care | Health Care | Baby's First Testjohndemello7
Baby's First Test is the nation's newborn screening education center for parents, health professionals, and the public on the newborn screening system.
Visit http://www.babysfirsttest.org/
Global Medical Cures™ | Genetic Testing Handbook
DISCLAIMER-
Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Versão em português da apresentação de Jane Squires, uma das autoras do ASQ-3 (sigla para Ages and Stages Questionnaires), método de avaliação infantil desenvolvido nos Estados Unidos e utilizado em mais de 18 países, apresentado pela Secretaria de Assuntos Estratégicos (SAE) promoveu no dia 05 de dezembro de 2011.
0103 Final Exam Readings 1 Final Examination Readings .docxmercysuttle
0103 Final Exam Readings 1
Final Examination Readings
WRC 0103
Fall 2013
Please write your name on the packet of readings you have downloaded from The
Writing Program website.
o Bring this packet to the final exam.
o You may underline, highlight, and annotate the readings.
o You may not bring thesis statements, outlines, prewriting, or drafts in any form to
the exam.
As you read, be aware that you will be writing a persuasive essay for your final.
You may bring a Standard English dictionary, in print form, not electronic form, to the
final. No translation dictionaries or translators will be allowed.
Be sure to bring this Works Cited page to the final.
No class time will be allotted for discussion of the readings
o You may, if you wish, discuss the readings outside of class with your classmates.
o You may not discuss them with your instructor.
If you haven’t done so already, turn in 2 blank blue books to your instructor.
o You will write your final essay in these blue books.
o Your instructor will return them to you on the day of the final.
Remember to write on only one side of each page.
Write “Final Draft” on the cover of the blue book(s) you want your instructor to read and
evaluate.
After completing the final essay, turn in to your instructor
o the reading packet
o used blue books
o the prompt
Your final exam will be in the same room as your semester class has been held.
Be sure to confirm the day and time of your final. You can
o Check your syllabus
o Check postings around campus
o Check ASAP
o Ask your instructor
o Check outside The Writing Program office, NPB
o Check on The Writing Program website: http://www.utsa.edu/twp/FinalExam.htm
http://www.utsa.edu/twp/FinalExam.htm
0103 Final Exam Readings 2
Reproductive Technology
Encyclopedia of Contemporary American Social Issues
Ed. Michael Shally-Jensen. Vol. 4: Environment, Science, and Technology. Santa Barbara, CA:
ABC-CLIO, 2011. p1602-1607. COPYRIGHT 2011 ABC-CLIO, LLC Anne Kingsley
In 1978 Louise Brown became the first “test tube” baby to be born using in vitro fertilization
(IVF). Her birth marked the advent of a rapidly advancing reproductive science, and it also
became a testament to a changing concept of creation. Her birth was not only a moment of
celebration but also one of controversy. For some, IVF opposed traditional or religious beliefs
about family and reproduction. Conception took place outside the body and outside the family
and was altered through medical intervention. Many of the practices used in IVF and other
assisted reproduction technologies (ART) challenged what was commonly thought of as the
standard or normal family: one mother, one father, and children. A process such as egg or sperm
donation, both of which take a third-party donor to create a fertilized embryo that will then be
introduced into the female body using IVF, was therefor ...
@EARLI19 paper on Professional Learning in the health sector in developing countries by Koula Charitonos (Open University, UK) and Allison Littlejohn (University of Glasgow, UK)
Similar to Suggested Teaching Approaches For Nbs 4 24 06 Ks (20)
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
1. Suggested Teaching Approaches for
Newborn Screening
Format 1: Point of Care (~ 5 min)
Overview Resources available at time of patient contact, to help learner care for patient and advance own knowledge of the topic.
Suggested GeneticTools “At-A-Glance” on newborn screening, www.genetictools.org/[link here]
educational material
GeneticTools overview of newborn screening and public health, http://www.genetests.org/servlet/access?
id=8888892&key=t0jmQ19e2e1jp&fcn=y&fw=pqY8&filename=/tools/concepts/screening.html
GeneTests overview of newborn screening, http://genetests.org/servlet/access?
id=8888891&key=rQfGzSggrmqxI&fcn=y&fw=3MwK&filename=/concepts/primer/primerusesof.html#newborn
o Click on the “Clinical Example” links for short cases
Next steps after a positive newborn screening test – Fact Sheets on specific conditions - American Academy of Pediatrics [4-22-06 -
should be posted on the AAP web site, http://www.aap.org within a month].
Fact sheets for professionals and parents about metabolic conditions detected using tandem mass spectrometry –
http://www.newbornscreening.info
Mini- topics [Case requiring immendiate follow-up]
Addressing common [Clinical suspician of condition detected by NBS in a bay or child who had NBS]
questions in clinical
precepting.
Suggested approach Have connection to Internet available. Choose a condition detectable by newborn screening. Use resources above to identify an information
source about that condition that can be read or skimmed in 5 minutes or less. unified access point with direct links to web-based resources
available in the clinic precepting environment.
ACGME/RRC Do these apply to topics covered in precepting?
requirements
Format 2: Morning Report (~ 20 min.)
Overview Brief informal discussion of case-based materials presenting major points regarding newborn screening. Could be led by faculty or chief/senior
resident. Would a program ever bring in a CGC or a medical geneticist to do this?
Suggested GeneticTools (www.genetictools.org) teaching cases. Each case includes key points, learning objectives, red flags, and descriptions of clinical care
educational material issues; risk assessment; genetic counseling and testing; interventions; ethical, legal, social, and cultural issues; and resources.
Cases about responding to positive newborn screening results:
o Case 10: Not passing a newborn hearing screen, http://www.genetests.org/servlet/access?
id=8888892&key=ZDwdXBfuvv8tu&fcn=y&fw=2XNz&filename=/tools/cases/hearingLoss-10/index.html
o Case 34: Sickle cell disease detected by newborn screening, http://www.genetests.org/servlet/access?
id=8888892&key=ZDwdXBfuvv8tu&fcn=y&fw=X9TK&filename=/tools/cases/sickle-34/index.html
o Case 35: Sickle cell trait detected by newborn screening. http://www.genetests.org/servlet/access?
id=8888892&key=ZDwdXBfuvv8tu&fcn=y&fw=hDo-&filename=/tools/cases/sickle-35/index.html
Revised 3/31/20064/24/2006 Page 1 of 4
Kerry Silvey, MA, CGC
Children’s Development & Rehabilitation Center, OHSU
2. Suggested Teaching Approaches for
Newborn Screening
Cases about other newborn screening issues:
o Case 11: Older sibling of a baby diagnosed with hearing loss by newborn screening subsequently diagnosed with hearing loss,
http://www.genetests.org/servlet/access?
id=8888892&key=ZDwdXBfuvv8tu&fcn=y&fw=6lvI&filename=/tools/cases/hearingLoss-11/index.html
o Case 20: Family asked to participate in a research study about detecting Type 1 diabetes mellitus by newborn screening, http://
www.genetests.org/servlet/access?
id=8888892&key=ZDwdXBfuvv8tu&fcn=y&fw=LRCv&filename=/tools/cases/diabetesType2-20/index.html
Fact sheets on next steps after a positive newborn screening test - American Academy of Pediatrics [4-22-06 - should be posted on the
AAP web site, http://www.aap.org within a month].
Fact sheets for professionals and parents about metabolic conditions detected using tandem mass spectrometry –
http://www.newbornscreening.info
Suggested pre- All attendees: Review your state’s newborn screening and Early Hearing Loss Detected and Intervention (EHDI) websites. Familiarize yourself with
reading your state’s resources for health care providers, parents, and who you can contact with questions about a patient’s newborn screening results.
Links to each states’ NBS program are on http://genes-r-us.uthscsa.edu.
Discussion leader: Same as for participants.
Suggested approach Informal discussion of case-based materials presenting major points regarding newborn screening. Could be led by faculty, chief/senior resident,
or in-house metabolic geneticist, pediatric endocrinologist, or pediatric hematologist. Some of the 5-minute mini-topics suggested for Point of Care
teaching (above) can be expanded, modified, or combined to work in a 20-minute teaching discussion. Add a 1 or 2-sentence case at the start to
introduce the topic, and spend more time asking questions and discussing each point. Examples below:
ACMG/RRC ??
requirements
Evaluation ??
Format 3: Noon Conference (~ 1 hour)
Overview Formal lecture-style presentation of information on newborn screening.
Suggested educational material [Still looking for the perfect resource]
Suggested pre- reading ?? Review your state’s newborn screening website. Familiarize yourself with your state’s resources for health care providers,
parents, and who you can contact with questions about a patient’s newborn screening results. Links to each states’ NBS program
are on http://genes-r-us.uthscsa.edu.
Suggested approach Formal lecture-style presentation of information on newborn screening. Your state’s newborn screening program follow-up
contact should be able to connect you with metabolic geneticists, pediatric endocrinologists, pediatric hematologists, and/or
Revised 3/31/20064/24/2006 Page 2 of 4
Kerry Silvey, MA, CGC
Children’s Development & Rehabilitation Center, OHSU
3. Suggested Teaching Approaches for
Newborn Screening
genetic counselors to speaker at a noon conference. Links to each states’ NBS programs are on http://genes-r-us.uthscsa.edu.
ACGME/RRC requirements ??
Evaluation ??
Revised 3/31/20064/24/2006 Page 3 of 4
Kerry Silvey, MA, CGC
Children’s Development & Rehabilitation Center, OHSU
4. Suggested Teaching Approaches for
Newborn Screening
Format 4: Self- Directed Learning
Overview Material available for learner self-study, via the Internet.
Suggested educational material AAFP 2005 Annual Clinical Focus: Genomics—video on newborn screening, http://www.aafp.org/x37667.xml
o CME series produced by the American Academy of Family Physicians
o 45-minute video viewed directly from the Internet (NB: requires high-speed Internet access)
o Uses a case example of a newborn diagnosed with cystic fibrosis through newborn screening.
o Discusses implications of using tandem mass spectrometry for newborn screening.
March of Dimes Website, www.marchofdimes.com
o Website has a separate section for Professionals & Researchers; also patient education pages
o Use Search function to find content of interest
o Includes pages on “What Providers Can Do,” links to each state’s newborn screening program
Suggested pre- reading ??
Suggested approach ??Material available for learner self-study, via the Internet.
ACGME/RRC requirements ??
Evaluation ??
Other Resources (more detail)
National Newborn Screening & Genetics Resource Center, http://genes- r-us.uthscsa.edu/index.htm
Revised 3/31/20064/24/2006 Page 4 of 4
Kerry Silvey, MA, CGC
Children’s Development & Rehabilitation Center, OHSU