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SUDDEN INFANT DEATH
SYNDROME(SIDS): A PRECISE
INSIGHT
PRESENTED BY:
VISHNU.R.NAIR,
5TH YEAR PHARM.D,
NATIONAL COLLEGE OF PHARMACY(NCP).
INDEX/ CONTENTS OF THIS PPT:
 MEDIA GALLERY
 GENERAL INTRODUCTION
 WHAT CAUSES CRIB DEATHS?
 RISK FACTORS FOR SIDS
 PREVENTIVE MEASURES FOR CRIB DEATHS
 REFERENCE/BIBLIOGRAPHY
MEDIA GALLERY
SUMMARIZED FLOWCHART OF SIDS
OCCURRENCE:
PATHOPHYSIOLOGY OF SIDS:
GENERAL INTRODUCTION
 Refers to “Unexplained death, especially during sleep, of a seemingly
healthy baby, less than a year old.”
 Also known as “CRIB DEATH”, since the infants often die in their cribs
 Usually the cause is unknown
 It is presumed that SIDS may be associated with ABNORMALITIES IN
THE PORTION OF AN INFANT’S BRAIN, that CONTROLS
BREATHING & AROUSAL FROM SLEEP.
WHAT CAUSES CRIB
DEATH??
 Combination of PHYSICAL & SLEEP ENVIRONMENTAL FACTORS 
increase an infant’s vulnerability to SIDS
 Factors vary from child to child
 Factors include:
A. PHYSICAL FACTORS
B. SLEEP ENVIRONMENTAL FACTORS
A. PHYSICAL FACTORS:
Include:
1. Brain abnormalities
2. Low birth weight
3. Respiratory infections
1. BRAIN ABNORMALITIES:
- Some infants  born with problems, that make them likely to die from
SIDS
- In many of such babies  portion of brain, that controls breathing &
arousal from sleep doesn’t work properly.
2. LOW BIRTH WEIGHT:
- Premature birth/ being part of multiple births  increase risk of
immaturation of baby’s brain  child has less control over automatic
processes like breathing & heart rate.
3. RESPIRATORY INFECTIONS:
- Many infants, who died from SIDS  had a cold in recent past  might
have contributed to breathing problems.
B. SLEEP ENVIRONMENTAL FACTORS:
- Items in a baby’s crib + his/her sleeping position  in combination with
baby’s physical problems  increases SIDS risk.
- Examples of such factors include:
1. SLEEPING ON STOMACH/SIDE
2. SLEEPING ON A SOFT SURFACE
3. SLEEPING WITH PARENTS.
1. SLEEPING ON STOMACH/SIDE:
- Babies  placed on their stomach/side  have more difficulty in breathing,
compared to those PLACED ON THEIR BACKS.
2. SLEEPING ON A SOFT SURFACE:
- Babies  lying “face-down” on a “fluffy comforter”/ “waterbed”  can block
his/her airway
- Draping a blanket over a baby’s head is also risky.
3. SLEEPING WITH PARENTS:
- While SIDS risk is lowered if an infant sleeps in the same room as his/her
parents  risk increases, if baby sleeps in the SAME BED(Partly, since
there are more soft surfaces to impair breathing!!!)
RISK FACTORS FOR SIDS
Include:
1. SEX: Boys are more likely to die from SIDS, compared to girls
2. AGE: Infants are more vulnerable to SIDS during their 2nd & 3rd months of
life
3. RACE: BLACKS, AMERICAN INDIANS/ ESKIMO infants are more likely
to die from SIDS
4. FAMILY HISTORY: Babies  who have had their siblings/ cousins die
from SIDS  are at high risk of SIDS.
5. SECONDHAND SMOKE:
- Babies  who live with smokers  have high risk of developing SIDS.
6. BEING PREMATURE:
- The following conditions can predispose a baby to die from SIDS:
a. Being born early
b. Having low birth weight
c. Combination of above.
7. MATERNAL FACTORS:
- Include:
a. Mother’s age< 20 years
b. Mother smokes cigarettes
c. Mother uses drugs/ is alcoholic
d. Mother had insufficient pre-natal care.
HOW TO PREVENT TRAGIC
CRIB DEATHS???
Include:
1. “BACK TO SLEEP”
2. KEEPING A CRIB AS BARE AS POSSIBLE
3. DON’T OVERHEAT BABY
4. BABY SHOULD SLEEP ALONE
5. BREAST-FEEDING OF BABY
6. AVOID BABY MONITORS & OTHER COMMERCIAL DEVICES
7. OFFERING A PACIFIER
1. “BACK TO SLEEP”:
- Place baby back to sleep, by resting on HIS/HER BACK, rather than that
on the STOMACH/SIDE.
- The above move is unnecessary when the baby is awake/ able to roll over
both ways without help
- DON’T ASSUME THAT OTHERS WILL PLACE YOUR BABY TO SLEEP
IN THE CORRECT POSITION  thus, insist on the same
- Advise baby-sitters & child-care personnel to NOT USE THE STOMACH
POSITION TO CALM AN UPSET BABY.
2. KEEPING CRIB AS BARE AS POSSIBLE:
- Use FIRM MATTRESS
- Avoid placing baby on a thick, fluffy padding(lambskin/ thick quilt)
- Avoid leaving the following inside the crib, which may interfere with
breathing, if baby’s face presses against them:
a. Pillows
b. Fluffy toys
c. Stuffed animals.
3. DON’T OVERHEAT BABY:
- To keep baby warm  use SLEEP SACK/ other sleep clothing, that does not
require additional covers
- Use LIGHT-WEIGHT BLANKETS
- Tuck blanket securely into foot of mattress, with sufficient length to cover
baby’s shoulders  then place baby inside the crib near the foot, covered
loosely with the blanket
- Avoid covering baby’s head.
4. BABY SHOULD SLEEP ALONE:
- Baby  sleeping in the same room as that of parents is a good move
- Adult beds  unsafe for infants!!!
- Baby  can become trapped & suffocate between headboard slats, the
space between mattress & bed frame, OR in the space between mattress &
wall.
- If baby sleeps in same bed as that of parents  there are chances that a
sleeping parent may accidentally roll over & cover baby’s nose & mouth 
can lead to suffocation.
5. BREAST-FEEDING OF BABY : A MUST!!!! :
- Breastfeeding for atleast 6 months  reduces SIDS risk.
6. AVOID BABY MONITORS & OTHER COMMERCIAL DEVICES :
- Usage of baby monitors & other commercial devices that claim to reduce
SIDS risk  should be avoided!
- The AMERICAN ACADEMY OF PEDIATRICS  discourage use of
monitors & other devices , citing their inefficacy & safety concerns.
7. OFFER A PACIFIER:
- Sucking on a pacifier at naptime & bedtime  reduces SIDS risk
- If mother is breastfeeding  wait to offer a pacifier, till her child is 3-4
weeks old
- If baby is not interested in the pacifier  don’t force it  try again another
day
- If pacifier falls out of baby’s mouth while he/she is sleeping  AVOID
POPPING IT BACK IN!!
REFERENCE/ BIBLIOGRAPHY:
1. https://www.mayoclinic.org/diseases-conditions/sudden-infant-death-
syndrome/symptoms-causes/syc-20352800
2. https://www.webmd.com/parenting/baby/what-is-sids#1
3. http://kidshealth.org/en/parents/sids.html
4. https://www.nhs.uk/conditions/sudden-infant-death-syndrome-sids/
5. https://www.emedicinehealth.com/sudden_infant_death_syndrome_sids/a
rticle_em.htm
6. Hymel KP. Distinguishing sudden infant death syndrome from child
abuse fatalities. Pediatrics. 2006 Jul. 118(1):421-7. [Medline].
7. Krous HF, Beckwith JB, Byard RW, Rognum TO, Bajanowski T, Corey T, et al.
Sudden infant death syndrome and unclassified sudden infant deaths: a definitional
and diagnostic approach. Pediatrics. 2004 Jul. 114(1):234-8. [Medline].
8. Paterson DS, Trachtenberg FL, Thompson EG, Belliveau RA, Beggs AH, Darnall R,
et al. Multiple serotonergic brainstem abnormalities in sudden infant death
syndrome. JAMA. 2006 Nov 1. 296(17):2124-32. [Medline].
9. Leiter JC, Böhm I. Mechanisms of pathogenesis in the Sudden Infant Death
Syndrome. Respir Physiol Neurobiol. 2007 Nov 15. 159(2):127-38. [Medline].
10. Ostfeld BM, Esposito L, Perl H, Hegyi T. Concurrent risks in sudden infant death
syndrome. Pediatrics. 2010 Mar. 125(3):447-53. [Medline].
THANK
YOU!!!

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Sudden infant death syndrome(SIDS)- By RxVichu!! ;) ;)

  • 1. SUDDEN INFANT DEATH SYNDROME(SIDS): A PRECISE INSIGHT PRESENTED BY: VISHNU.R.NAIR, 5TH YEAR PHARM.D, NATIONAL COLLEGE OF PHARMACY(NCP).
  • 2. INDEX/ CONTENTS OF THIS PPT:  MEDIA GALLERY  GENERAL INTRODUCTION  WHAT CAUSES CRIB DEATHS?  RISK FACTORS FOR SIDS  PREVENTIVE MEASURES FOR CRIB DEATHS  REFERENCE/BIBLIOGRAPHY
  • 4.
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  • 6. SUMMARIZED FLOWCHART OF SIDS OCCURRENCE:
  • 8.
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  • 14.  Refers to “Unexplained death, especially during sleep, of a seemingly healthy baby, less than a year old.”  Also known as “CRIB DEATH”, since the infants often die in their cribs  Usually the cause is unknown  It is presumed that SIDS may be associated with ABNORMALITIES IN THE PORTION OF AN INFANT’S BRAIN, that CONTROLS BREATHING & AROUSAL FROM SLEEP.
  • 16.  Combination of PHYSICAL & SLEEP ENVIRONMENTAL FACTORS  increase an infant’s vulnerability to SIDS  Factors vary from child to child  Factors include: A. PHYSICAL FACTORS B. SLEEP ENVIRONMENTAL FACTORS
  • 17. A. PHYSICAL FACTORS: Include: 1. Brain abnormalities 2. Low birth weight 3. Respiratory infections
  • 18. 1. BRAIN ABNORMALITIES: - Some infants  born with problems, that make them likely to die from SIDS - In many of such babies  portion of brain, that controls breathing & arousal from sleep doesn’t work properly. 2. LOW BIRTH WEIGHT: - Premature birth/ being part of multiple births  increase risk of immaturation of baby’s brain  child has less control over automatic processes like breathing & heart rate.
  • 19. 3. RESPIRATORY INFECTIONS: - Many infants, who died from SIDS  had a cold in recent past  might have contributed to breathing problems.
  • 20. B. SLEEP ENVIRONMENTAL FACTORS: - Items in a baby’s crib + his/her sleeping position  in combination with baby’s physical problems  increases SIDS risk. - Examples of such factors include: 1. SLEEPING ON STOMACH/SIDE 2. SLEEPING ON A SOFT SURFACE 3. SLEEPING WITH PARENTS.
  • 21. 1. SLEEPING ON STOMACH/SIDE: - Babies  placed on their stomach/side  have more difficulty in breathing, compared to those PLACED ON THEIR BACKS. 2. SLEEPING ON A SOFT SURFACE: - Babies  lying “face-down” on a “fluffy comforter”/ “waterbed”  can block his/her airway - Draping a blanket over a baby’s head is also risky.
  • 22. 3. SLEEPING WITH PARENTS: - While SIDS risk is lowered if an infant sleeps in the same room as his/her parents  risk increases, if baby sleeps in the SAME BED(Partly, since there are more soft surfaces to impair breathing!!!)
  • 24. Include: 1. SEX: Boys are more likely to die from SIDS, compared to girls 2. AGE: Infants are more vulnerable to SIDS during their 2nd & 3rd months of life 3. RACE: BLACKS, AMERICAN INDIANS/ ESKIMO infants are more likely to die from SIDS 4. FAMILY HISTORY: Babies  who have had their siblings/ cousins die from SIDS  are at high risk of SIDS.
  • 25. 5. SECONDHAND SMOKE: - Babies  who live with smokers  have high risk of developing SIDS. 6. BEING PREMATURE: - The following conditions can predispose a baby to die from SIDS: a. Being born early b. Having low birth weight c. Combination of above.
  • 26. 7. MATERNAL FACTORS: - Include: a. Mother’s age< 20 years b. Mother smokes cigarettes c. Mother uses drugs/ is alcoholic d. Mother had insufficient pre-natal care.
  • 27. HOW TO PREVENT TRAGIC CRIB DEATHS???
  • 28. Include: 1. “BACK TO SLEEP” 2. KEEPING A CRIB AS BARE AS POSSIBLE 3. DON’T OVERHEAT BABY 4. BABY SHOULD SLEEP ALONE 5. BREAST-FEEDING OF BABY 6. AVOID BABY MONITORS & OTHER COMMERCIAL DEVICES 7. OFFERING A PACIFIER
  • 29. 1. “BACK TO SLEEP”: - Place baby back to sleep, by resting on HIS/HER BACK, rather than that on the STOMACH/SIDE. - The above move is unnecessary when the baby is awake/ able to roll over both ways without help - DON’T ASSUME THAT OTHERS WILL PLACE YOUR BABY TO SLEEP IN THE CORRECT POSITION  thus, insist on the same - Advise baby-sitters & child-care personnel to NOT USE THE STOMACH POSITION TO CALM AN UPSET BABY.
  • 30. 2. KEEPING CRIB AS BARE AS POSSIBLE: - Use FIRM MATTRESS - Avoid placing baby on a thick, fluffy padding(lambskin/ thick quilt) - Avoid leaving the following inside the crib, which may interfere with breathing, if baby’s face presses against them: a. Pillows b. Fluffy toys c. Stuffed animals.
  • 31. 3. DON’T OVERHEAT BABY: - To keep baby warm  use SLEEP SACK/ other sleep clothing, that does not require additional covers - Use LIGHT-WEIGHT BLANKETS - Tuck blanket securely into foot of mattress, with sufficient length to cover baby’s shoulders  then place baby inside the crib near the foot, covered loosely with the blanket - Avoid covering baby’s head.
  • 32. 4. BABY SHOULD SLEEP ALONE: - Baby  sleeping in the same room as that of parents is a good move - Adult beds  unsafe for infants!!! - Baby  can become trapped & suffocate between headboard slats, the space between mattress & bed frame, OR in the space between mattress & wall. - If baby sleeps in same bed as that of parents  there are chances that a sleeping parent may accidentally roll over & cover baby’s nose & mouth  can lead to suffocation.
  • 33. 5. BREAST-FEEDING OF BABY : A MUST!!!! : - Breastfeeding for atleast 6 months  reduces SIDS risk. 6. AVOID BABY MONITORS & OTHER COMMERCIAL DEVICES : - Usage of baby monitors & other commercial devices that claim to reduce SIDS risk  should be avoided! - The AMERICAN ACADEMY OF PEDIATRICS  discourage use of monitors & other devices , citing their inefficacy & safety concerns.
  • 34. 7. OFFER A PACIFIER: - Sucking on a pacifier at naptime & bedtime  reduces SIDS risk - If mother is breastfeeding  wait to offer a pacifier, till her child is 3-4 weeks old - If baby is not interested in the pacifier  don’t force it  try again another day - If pacifier falls out of baby’s mouth while he/she is sleeping  AVOID POPPING IT BACK IN!!
  • 35. REFERENCE/ BIBLIOGRAPHY: 1. https://www.mayoclinic.org/diseases-conditions/sudden-infant-death- syndrome/symptoms-causes/syc-20352800 2. https://www.webmd.com/parenting/baby/what-is-sids#1 3. http://kidshealth.org/en/parents/sids.html 4. https://www.nhs.uk/conditions/sudden-infant-death-syndrome-sids/ 5. https://www.emedicinehealth.com/sudden_infant_death_syndrome_sids/a rticle_em.htm 6. Hymel KP. Distinguishing sudden infant death syndrome from child abuse fatalities. Pediatrics. 2006 Jul. 118(1):421-7. [Medline].
  • 36. 7. Krous HF, Beckwith JB, Byard RW, Rognum TO, Bajanowski T, Corey T, et al. Sudden infant death syndrome and unclassified sudden infant deaths: a definitional and diagnostic approach. Pediatrics. 2004 Jul. 114(1):234-8. [Medline]. 8. Paterson DS, Trachtenberg FL, Thompson EG, Belliveau RA, Beggs AH, Darnall R, et al. Multiple serotonergic brainstem abnormalities in sudden infant death syndrome. JAMA. 2006 Nov 1. 296(17):2124-32. [Medline]. 9. Leiter JC, Böhm I. Mechanisms of pathogenesis in the Sudden Infant Death Syndrome. Respir Physiol Neurobiol. 2007 Nov 15. 159(2):127-38. [Medline]. 10. Ostfeld BM, Esposito L, Perl H, Hegyi T. Concurrent risks in sudden infant death syndrome. Pediatrics. 2010 Mar. 125(3):447-53. [Medline].