Energy Absorption in Radiobiology
Ionization vs. Excitation
Ionizing Versus Non-ionizing Radiation
Absorption Mechanisms
Ionization by alpha particle, Xray & neutron
Energy Absorption in Radiobiology
Ionization vs. Excitation
Ionizing Versus Non-ionizing Radiation
Absorption Mechanisms
Ionization by alpha particle, Xray & neutron
A particle accelerator
Sends charged particles, which constantly accelerate through a ‘Dee’, through a circular path until they are (most likely) directed towards a designated target for a specific purpose
A particle accelerator
Sends charged particles, which constantly accelerate through a ‘Dee’, through a circular path until they are (most likely) directed towards a designated target for a specific purpose
FLESCH INDEX AND SYS AND OS MODULE IN PYTHON PROGRAMMING LANGUAGEJustin George
FLESCH INDEX AND SYS AND OS MODULE IN PYTHON PROGRAMMING LANGUAGE. Details with explanation of sys and os module. Also with Flesch index program and execution result.
21st CENTURY SKILLS BASED ON OUR CURRENT SOCIAL LIFE Justin George
21st CENTURY SKILLS BASED ON OUR CURRENT SOCIAL LIFE. Life Skill is needed in our day-to-day life. Such as effective communication in our team or workplace, Critical thinking and creativity for our work firm and field of expertise, Lateral Thinking and Myths of Creativity, Collaboration, Intuition, Imagination, Experience in our Social life. By the effort of a small group of Engineering Students from Kerala, India.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
3. SCINTILLATION DETECTORS
• Detects the light emitted by a crystal
subjected to ionizing radiation
a) Organic scintillation detector.
b) Inorganic scintillation detector.
• It can be used for counting as well as for
energy analysis.
4. Gamma ray Spectrometer
• Sodium iodide scintillation spectrometer is the
most successful and popular method in
gamma ray spectroscopy.
• Thallium activated sodium iodide crystals are
used as scintillators.
• The scintillation detector is coupled to nuclear
electronic system.
7. Single Channel Analyser
• It is a pulse-height analyser.
• Analysis is made by taking the readings for
one channel at a time.
• There are two discriminators.
9. • The observed spectrum is complex in nature.
• The various absorption processes involved are
a) Photoelectric absorption.
b) Compton effect absorption.
c) Absorption by pair production.
10. • The widening of line into a Gaussian shaped
profile is due to the statistical fluctuations in
the various processes which convert gamma
rays into an output pulse.
• The processes contribute to statistical
fluctuations are
11. • Conversion of incident gamma rays into
luminescence photons
• Light transmission and collection by
photocathode
• Conversion of light into photoelectrons
• Focussing of photoelectrons on dynodes
• Multiplication of electrons
12. Gamma ray detector should
have
• High efficiency of detection.
• Good energy resolution power.
• Linear response to electron.
• Good mechanical and electrical
stability.
13. Characteristics of energy spectrometer
• Linearity :The amplitude of the output
pulse must be directly proportional to
the original number of scintillation and
thus in turn to the energy deposited
• Stability :Gain of each dynode stage
depends on the voltage difference ,any
change in high voltage will cause a
variation in the output pulse.
14. Calibration of gamma ray
spectrometer
• We calibrate the spectrometer to 2 Mev using
the standard source 137
𝐶𝑠.
• The gain is set such that the peak count will
appear on the scale.
• The count is noted for such channel and is
checked for the peak.
• If there is any deviation we repeat the above
steps so that peak is obtained at 33 𝑟𝑑
channel.
15. • The channel around photopeak are set and
counts are noted.
• This is repeated for different sources.
• Resolution for each photopeak is determined.
• A plot of resolution versus energy is made
which should yield a straight line.
16. • Here we have two potentiometers with 10
turns each.
• One acts as ULD and other as LLD.
• ULD : 0 to 1V.
• LLD : 0 to 10V.
• For LLD-1 channel=20 keV
17. AIM
• To study the linearity of gamma ray
spectrometer using SCA and determination of
energy of unknown source.
19. Isotop Energy in keV
137
𝐶𝑠 662
133
𝐵𝑎 365
60
𝐶𝑜 1170
57
𝐶𝑜 122
22
𝑁𝑎 511
20. PROCEDURE
• The energies of various gamma sources are
provided.
• Calibration of gamma ray spectrometer to
2 MeV has been done.
• 137
𝐶𝑠 is treated as the standard source the
counts per 30 second for the entire spectrum
is noted down.
• Photopeak is obtained at channel no.33.
21. • Similarly photopeak for all other known
sources are noted down.
• Then counts per 30 second for the entire
spectrum for the unknown source is recorded.
• For all these sources a graph is plotted
between counts per 30 second and channel
number.
• Thus we obtain the photopeaks.
22. • Now a plot of energy versus peak channel
number is made which will yield a straight
line.
• From this plot we can determine the energy of
the given unknown source.