Spondylolisthesis is the forward displacement of a vertebra, most commonly the fifth lumbar vertebra. It occurs when a vertebra slips out of proper position due to a fracture, birth defect, injury, or arthritis which causes abnormal wear on bones and cartilage. Spondylolisthesis is classified based on its cause as isthmic, degenerative, traumatic, or dysplastic and is graded based on the percentage of vertebral slippage. Symptoms include lower back pain, muscle tightness, and pain or numbness in the thighs and buttocks. Treatment options involve conservative measures like physical therapy or surgery.