Nutraceuticals & Cosmeceuticals
1
CONTENTS:
I. NUTRACEUTICALS (INTRODUCTION)
II. CLASSIFICATION OF NUTRACEUTICALS
III. HERBSAS FUNCTIONAL FOODS
2
 INTRODUCTION:
 The term “Nutraceutical” was coined from “Nutrition” &
“Pharmaceutical” in 1989 by
Stephen DeFelice,
Founder and Chairman of the
Foundation for Innovation in Medicine (FIM).
 Other words used in the context:
Dietary supplementation, Functional, Multi-functional Foods, etc.
3
 Nutraceutical can be defined as
“According to De Felice, nutraceutical can be defined as, "a
food (or part of a food) that provides medical or health
benefits, including the prevention and/or treatment of a
disease."
4
Classification of Nutraceuticals
Nutraceuticals can be classified based on:
 Natural source
 Pharmacological conditions
 Chemical constitution
5
CLASSIFICATION BASED ON CHEMICAL
GROUPS
1. Inorganic mineral supplements
2. Vitamin supplements
3. Digestive enzymes
4. Probiotics
5. Prebiotics
6. Dietary fibres
7. Cereal and grains
8. Health drinks
9. Antioxidants
6
10. Phytochemicals
a) Polysaccharides,
b) Isoprenoids
c) Flavanoids
d) Phenolics
e) Fattyacids
f) Lipids
g) Proteins
11. Herbs as a functional foods
7
1. Inorganic Mineral Supplements
 Large number of elements controls variety of physiological and
biochemical functions of human body. Most of these minerals are provided
through the diet but their deficiency in diet may develop variety of health
related problems and diseases. These Minerals are
 Calcium
 Magnesium
 Manganese
 Boron
 Copper
 Zinc
 Phosphorus
 Silicon
8
2. Vitamins Supplements
 Vitamins are the complex substances of organic origin which
in small quantity are necessary for the maintenance of human
and animal life. Some of the water soluble and water
insoluble vitamins are
HEALTH BENEFITS OFVITAMINS
9
10
3. Digestive Enzymes
 Variety of digestive enzymes can be used as digestive aid to
help and absorb digestive food material.These enzymes are
 Pepsin
 Pancreatin
 Pancrilipase
 Amylase
 Papain
 Bromelain
11
4. Probiotics
 Probiotics are Live microorganisms which, when
administered in adequate amounts, confer a health benefit on
the host.
 Species of Lactobacillus and Bifidobacterium are most
commonly used as probiotics.
12
5. Prebiotics
 Food components that escape digestion by normal human
digestive enzyme and safely in intact form reach the colon
after passage through the stomach and small intestine, where
they selectively promote the growth of probiotics.
13
6. Dietary fibers
 Dietary fibers plays crucial role in keeping good health in
human individuals and animals . Fibers are those parts of the
plant, leave, stem and fruits which can not be digested or
absorbed in the body which are necessary for our body to
function properly.
 Types
1.Water soluble fibres 2. Water insoluble fibres
Daily recommended intake is 30-40 gms
14
Sources
15
16
7. Health Drinks
 Fast developing era of functional foods
 Health drinks are fortified with vitamins A, C, E and herbal
extracts
 Drinks containing caffeine vitalize body and mind, increases
concentration and reaction speed
17
8. Antioxidants
 Antioxidants are nutraceuticals whose deficiency states are
associated with variety of disease conditions , such as cardiovascular
diseases, diabetes, cataracts, rheumatoid arthritis,Alzhiemher
disease and many others.
Naturally occurring antioxidants
 Vitamin C ( Citrus fruits)
 Lycopene(Tomatoes)
 β- carotenes(carrots,green vegetables)
 Catechins(green tea polyphenols)
 Liquiritin(Liquirice)
 Naringin( Citrus fruits)
18
9. Polyunsaturated fatty acids
 Human body is capable of synthesizing most of the fatty acids
it needs except the two major polyunsaturated fatty
acids(PUFA), i.e omega-3-fattyacid and omega-6-fattyacid.
These fattyacids are required to be supplemented from diet.
Functions:
 Regulate blood pressure
 Regulate heart rate
 Blood clotting and immune system
Sources: Cold water fishes,dark green leafy vegetables,
Flaxseed oils and in certain vegetables.
19
Herbs as Functional Foods
20
 1. FLAX SEEDS (Alsi)
B.O:Linum usitatissimum
Family: Linaceae
Medicinal Importance
 Prevents mammary, colon and rectal cancers. Reduces BP in
hypertensive patients.
 Reduces diabetes and coronary heart diseases.
21
 2. Ginko
B.O: Ginko biloba
Family:Ginkoaceae
Medicinal Importance
 a. In treating asthma, impairment of memory.
 b. Leaves are able to alleviate the
22
 3. Spirulina
 Blue green Algae obtained from
Spindina platensis
Family: Oscillatoriacae
Medicinal Importance
 Immuno-stimulant activity
 Management of HIV and other viral infections such as herpes, influenza,
mumps
 To treat arthritis
 Atherosclerosis
 Anti-diabetic activity
 Anti aging agent
23
 4. Karela
B.O: Momordica charantia
Family: Cucurbitaceae
Medicinal Importance
i) Hypoglycemic effect
Extract of karela increases rate of glycogen synthesis by 4-5 fold
in liver.
24
 5.Turmeric (Haldi)
 B.O: Curcuma longa
Family: Zingiberaceae
Medicinal Importance
 Hepatoprotective activity
 Inhibitor of Integrase enzyme of HIV virus
25
 6. Fenugreek (Maithi dana)
 B.O: Trigonella foenum-graceum
 Family: Leguminosae
 Medicinal Importance:
 In treatment of anorexia
 Gastritis.
 Laxative
 Expectorant,
 Demulcent properties.
 Shows hypoglycemic properties
 Hypocholesterolemic
26
 7. Ginseng
B.O: Panax ginseng
Family:Araliaceae
Medicinal Importance
27
8. Black cohosh
 B.O: Cimicifuge racemosa
 Family: Ranunculaceae
 Part used: Root and rhizome
Medicinal Importance:
• Antirheumatic
• Anti-tussive
• Sedative
• Emmenagogue
28
COSMECEUTICALS
29
DEFINITION
“ Cosmeceuticals are topical cosmetic-pharmaceutical
hybrids intended to enhance the beauty through ingredients
that provide additional health related functions or benefits.”
They are applied topically as as cosmetics but contains
ingredients that influence the skin biological functions.
30
A. Skin Cosmeceuticals
 Cosmetics and skin care products are the part of everybody
grooming.
 Protecting and preserving the skin is good to health
 Cosmeceuticals being cosmetic products having medicinal or
drug like benefits are able to affect the biological functioning
of skin owing to type of functional ingredients they contain
 Skin cosmeceuticals improves the texture of the skin by
encouraging collagen growth by combating harmful effects of
free radicals, maintain keratin structure in good condition
and making the skin healthier.
31
l
 Some of the important pharmaceutical contents are
1.Vitamins:
Action:Antioxidant
VitA, C and E
2. α-Hydroxy acids( AHAs):
Action: Exfoliates and improves circulation
Friut acids( Lactic acid, citric acid, tartaric acid, maleic acid)
32
3. β-Hydroxy acid( BHAs)
Action:Antibacterial
Salicylic acid
4. Essential fatty acids
Action: Smoothen, moisturizes and protects
Linoleic, Linolenic and Arachidonic acids
5.Aloe vera
Action: Soften skin
Aloe vera
33
6.Arnica
Action:Astringent and soothes
Arnica montana
7.Calendula
Action: Soothes, soften and promotes skin cell formation
Calendula officinalis
8. β-Bisabolol
Action:Anti-inflammatory,Anti-bacterial and calms skin
irritation
Chamomile flower
34
9. Green tea extract
Action:Antioxidant
Green tae
10. Licorice extract
Action:Skin whitening properties, antioxidant, antimicrobial, and anti-
inflammatory
Glycyrrhiza glabra
11.Dry extract fromYarrow:
Action:Traetment of oily hairs
Achillea mellifolium
12. Pycnogenol
Action: Antiaging effect
Grape seed extract
35
1. SUNSCREENS
Sunscreens are used to protect the skin from the harmful effects
of the sun.They help to prevent sunburn and premature aging
(e.g., wrinkles , leathery skin). Sunscreens also help to decrease
the risk of skin cancer and also of sunburn-like skin reactions
(sun sensitivity) caused by some medications (e.g.,
tetracyclines, sulfa drugs, phenothiazines such
as chlorpromazine ).
36
37
 The active ingredients in sunscreens work either by
absorbing the sun's ultraviolet (UV) radiation,, preventing it
from reaching the deeper layers of the skin, or by reflecting
the radiation.
Some commercially available sunscreens are
Benzophenone 8 (Block UVB and short wave UVA)
Neo Heliopan MA (UVA absorber)
Parsol MCX (UVB absorber)
38
2. MOISTURIZERS
FUNCTION
 Smooth out the age lines
 Help brighten and tone the delicate skin
Healthy Remedies Balancing Lotions has been created for
menupaausal women containing ingredients which diminishes the
apperance of fine lines and wrinkles, and moisturize the dry skin.
Some of those ingredients includes:
Black cohosh
Soya extract
VitaminA and E
39
3. BLEACHING AGENTS
 Bleaching agents are used for bleaching/fading the various
marks and act to block the formation of skin pigment
melanin.
 HYDROQUINONE: Used for bleaching brown marks and
melasma
 KOJIC ACID: Extracted from mushrooms is less effective
agent and may be compounded with topical steroids.
40
B.Hair Cosmeceuticals
 One can modify the length; color and style of hair according to how
one wish to appear. Hair care, color, and style play an important
role in people'sphysical appearance and self-perception.
 Cosmetics for the treatment of hair are applied topically to the
scalp and hair
Hair cosmeceuticals are used for
 Treatment of dandruff
 Traetment of oily hairs (Achillea millefolium)
 ,Yarrow
 Alopecia (Minoxidil)
 To treat Fungal infections( ketoconazole)
41

Share Nutraceuticals & Cosmeceuticals.pptx

  • 1.
  • 2.
    CONTENTS: I. NUTRACEUTICALS (INTRODUCTION) II.CLASSIFICATION OF NUTRACEUTICALS III. HERBSAS FUNCTIONAL FOODS 2
  • 3.
     INTRODUCTION:  Theterm “Nutraceutical” was coined from “Nutrition” & “Pharmaceutical” in 1989 by Stephen DeFelice, Founder and Chairman of the Foundation for Innovation in Medicine (FIM).  Other words used in the context: Dietary supplementation, Functional, Multi-functional Foods, etc. 3
  • 4.
     Nutraceutical canbe defined as “According to De Felice, nutraceutical can be defined as, "a food (or part of a food) that provides medical or health benefits, including the prevention and/or treatment of a disease." 4
  • 5.
    Classification of Nutraceuticals Nutraceuticalscan be classified based on:  Natural source  Pharmacological conditions  Chemical constitution 5
  • 6.
    CLASSIFICATION BASED ONCHEMICAL GROUPS 1. Inorganic mineral supplements 2. Vitamin supplements 3. Digestive enzymes 4. Probiotics 5. Prebiotics 6. Dietary fibres 7. Cereal and grains 8. Health drinks 9. Antioxidants 6
  • 7.
    10. Phytochemicals a) Polysaccharides, b)Isoprenoids c) Flavanoids d) Phenolics e) Fattyacids f) Lipids g) Proteins 11. Herbs as a functional foods 7
  • 8.
    1. Inorganic MineralSupplements  Large number of elements controls variety of physiological and biochemical functions of human body. Most of these minerals are provided through the diet but their deficiency in diet may develop variety of health related problems and diseases. These Minerals are  Calcium  Magnesium  Manganese  Boron  Copper  Zinc  Phosphorus  Silicon 8
  • 9.
    2. Vitamins Supplements Vitamins are the complex substances of organic origin which in small quantity are necessary for the maintenance of human and animal life. Some of the water soluble and water insoluble vitamins are HEALTH BENEFITS OFVITAMINS 9
  • 10.
  • 11.
    3. Digestive Enzymes Variety of digestive enzymes can be used as digestive aid to help and absorb digestive food material.These enzymes are  Pepsin  Pancreatin  Pancrilipase  Amylase  Papain  Bromelain 11
  • 12.
    4. Probiotics  Probioticsare Live microorganisms which, when administered in adequate amounts, confer a health benefit on the host.  Species of Lactobacillus and Bifidobacterium are most commonly used as probiotics. 12
  • 13.
    5. Prebiotics  Foodcomponents that escape digestion by normal human digestive enzyme and safely in intact form reach the colon after passage through the stomach and small intestine, where they selectively promote the growth of probiotics. 13
  • 14.
    6. Dietary fibers Dietary fibers plays crucial role in keeping good health in human individuals and animals . Fibers are those parts of the plant, leave, stem and fruits which can not be digested or absorbed in the body which are necessary for our body to function properly.  Types 1.Water soluble fibres 2. Water insoluble fibres Daily recommended intake is 30-40 gms 14
  • 15.
  • 16.
  • 17.
    7. Health Drinks Fast developing era of functional foods  Health drinks are fortified with vitamins A, C, E and herbal extracts  Drinks containing caffeine vitalize body and mind, increases concentration and reaction speed 17
  • 18.
    8. Antioxidants  Antioxidantsare nutraceuticals whose deficiency states are associated with variety of disease conditions , such as cardiovascular diseases, diabetes, cataracts, rheumatoid arthritis,Alzhiemher disease and many others. Naturally occurring antioxidants  Vitamin C ( Citrus fruits)  Lycopene(Tomatoes)  β- carotenes(carrots,green vegetables)  Catechins(green tea polyphenols)  Liquiritin(Liquirice)  Naringin( Citrus fruits) 18
  • 19.
    9. Polyunsaturated fattyacids  Human body is capable of synthesizing most of the fatty acids it needs except the two major polyunsaturated fatty acids(PUFA), i.e omega-3-fattyacid and omega-6-fattyacid. These fattyacids are required to be supplemented from diet. Functions:  Regulate blood pressure  Regulate heart rate  Blood clotting and immune system Sources: Cold water fishes,dark green leafy vegetables, Flaxseed oils and in certain vegetables. 19
  • 20.
  • 21.
     1. FLAXSEEDS (Alsi) B.O:Linum usitatissimum Family: Linaceae Medicinal Importance  Prevents mammary, colon and rectal cancers. Reduces BP in hypertensive patients.  Reduces diabetes and coronary heart diseases. 21
  • 22.
     2. Ginko B.O:Ginko biloba Family:Ginkoaceae Medicinal Importance  a. In treating asthma, impairment of memory.  b. Leaves are able to alleviate the 22
  • 23.
     3. Spirulina Blue green Algae obtained from Spindina platensis Family: Oscillatoriacae Medicinal Importance  Immuno-stimulant activity  Management of HIV and other viral infections such as herpes, influenza, mumps  To treat arthritis  Atherosclerosis  Anti-diabetic activity  Anti aging agent 23
  • 24.
     4. Karela B.O:Momordica charantia Family: Cucurbitaceae Medicinal Importance i) Hypoglycemic effect Extract of karela increases rate of glycogen synthesis by 4-5 fold in liver. 24
  • 25.
     5.Turmeric (Haldi) B.O: Curcuma longa Family: Zingiberaceae Medicinal Importance  Hepatoprotective activity  Inhibitor of Integrase enzyme of HIV virus 25
  • 26.
     6. Fenugreek(Maithi dana)  B.O: Trigonella foenum-graceum  Family: Leguminosae  Medicinal Importance:  In treatment of anorexia  Gastritis.  Laxative  Expectorant,  Demulcent properties.  Shows hypoglycemic properties  Hypocholesterolemic 26
  • 27.
     7. Ginseng B.O:Panax ginseng Family:Araliaceae Medicinal Importance 27
  • 28.
    8. Black cohosh B.O: Cimicifuge racemosa  Family: Ranunculaceae  Part used: Root and rhizome Medicinal Importance: • Antirheumatic • Anti-tussive • Sedative • Emmenagogue 28
  • 29.
  • 30.
    DEFINITION “ Cosmeceuticals aretopical cosmetic-pharmaceutical hybrids intended to enhance the beauty through ingredients that provide additional health related functions or benefits.” They are applied topically as as cosmetics but contains ingredients that influence the skin biological functions. 30
  • 31.
    A. Skin Cosmeceuticals Cosmetics and skin care products are the part of everybody grooming.  Protecting and preserving the skin is good to health  Cosmeceuticals being cosmetic products having medicinal or drug like benefits are able to affect the biological functioning of skin owing to type of functional ingredients they contain  Skin cosmeceuticals improves the texture of the skin by encouraging collagen growth by combating harmful effects of free radicals, maintain keratin structure in good condition and making the skin healthier. 31
  • 32.
    l  Some ofthe important pharmaceutical contents are 1.Vitamins: Action:Antioxidant VitA, C and E 2. α-Hydroxy acids( AHAs): Action: Exfoliates and improves circulation Friut acids( Lactic acid, citric acid, tartaric acid, maleic acid) 32
  • 33.
    3. β-Hydroxy acid(BHAs) Action:Antibacterial Salicylic acid 4. Essential fatty acids Action: Smoothen, moisturizes and protects Linoleic, Linolenic and Arachidonic acids 5.Aloe vera Action: Soften skin Aloe vera 33
  • 34.
    6.Arnica Action:Astringent and soothes Arnicamontana 7.Calendula Action: Soothes, soften and promotes skin cell formation Calendula officinalis 8. β-Bisabolol Action:Anti-inflammatory,Anti-bacterial and calms skin irritation Chamomile flower 34
  • 35.
    9. Green teaextract Action:Antioxidant Green tae 10. Licorice extract Action:Skin whitening properties, antioxidant, antimicrobial, and anti- inflammatory Glycyrrhiza glabra 11.Dry extract fromYarrow: Action:Traetment of oily hairs Achillea mellifolium 12. Pycnogenol Action: Antiaging effect Grape seed extract 35
  • 36.
    1. SUNSCREENS Sunscreens areused to protect the skin from the harmful effects of the sun.They help to prevent sunburn and premature aging (e.g., wrinkles , leathery skin). Sunscreens also help to decrease the risk of skin cancer and also of sunburn-like skin reactions (sun sensitivity) caused by some medications (e.g., tetracyclines, sulfa drugs, phenothiazines such as chlorpromazine ). 36
  • 37.
  • 38.
     The activeingredients in sunscreens work either by absorbing the sun's ultraviolet (UV) radiation,, preventing it from reaching the deeper layers of the skin, or by reflecting the radiation. Some commercially available sunscreens are Benzophenone 8 (Block UVB and short wave UVA) Neo Heliopan MA (UVA absorber) Parsol MCX (UVB absorber) 38
  • 39.
    2. MOISTURIZERS FUNCTION  Smoothout the age lines  Help brighten and tone the delicate skin Healthy Remedies Balancing Lotions has been created for menupaausal women containing ingredients which diminishes the apperance of fine lines and wrinkles, and moisturize the dry skin. Some of those ingredients includes: Black cohosh Soya extract VitaminA and E 39
  • 40.
    3. BLEACHING AGENTS Bleaching agents are used for bleaching/fading the various marks and act to block the formation of skin pigment melanin.  HYDROQUINONE: Used for bleaching brown marks and melasma  KOJIC ACID: Extracted from mushrooms is less effective agent and may be compounded with topical steroids. 40
  • 41.
    B.Hair Cosmeceuticals  Onecan modify the length; color and style of hair according to how one wish to appear. Hair care, color, and style play an important role in people'sphysical appearance and self-perception.  Cosmetics for the treatment of hair are applied topically to the scalp and hair Hair cosmeceuticals are used for  Treatment of dandruff  Traetment of oily hairs (Achillea millefolium)  ,Yarrow  Alopecia (Minoxidil)  To treat Fungal infections( ketoconazole) 41