SlideShare a Scribd company logo
Research: thoughts on a personal experience. Dany Morisset [email_address] http://www.nib.si/en/
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Where is Slovenia? Shanghai Slovenia
Slovenia
Italy Germany Venezzia (Venice)
Slovenia (Slovenija) GENERAL INFORMATION Area: ............. ............. 20,273 km2  (80km x 260 km) 7,037km2 for Shanghai (city) Forest: .......... ............. 10,124 km2  (49.9%)   Vineyards: ......... ......... 216 km2  Length of coast:..........46.6 km  Capital: ........... ........... Ljubljana Population: ........ ... .....2 ,023,000 (2008) 18,450,000 in Shanghai (2007) Language: ........ ........ .Slovene  Currency: ....... ....... ....Euro, 1 January 2007 Education: ........... ...... Universities in Ljubljana , Nova Gorica  and Maribor  cca 90,000  students
Triglav, the highest Slovenian mountain  Bled, jewel of the Julian Alps  Ljubljana, the capital city  Rafting on the Soča River
Piran, Tartini’s coastal town  Piran bay Julian Alps
Postojna Cave  Lipica horses  Proteus anguinus  or human fish Karstic land in Škocjan park
Vineyard from Štajerska Region  Slovenian specialities  Slovenian wine producing
National Institute of Biology   at the Biological Centre  in  Ljubljana Italy Germany Venezzia (Venice)
NIB is the leading institution for basic and applied research in biological sciences in Slovenia… and… the third largest institution in the field of natural sciences in Slovenia!
Mission   NIB is a public research institute, established by the  Republic of Slovenia with the mission: - to create new (basic) knowledge on the field of  biology and related natural sciences; - to transfer new knowledge into use for improvement  of the quality of life (to enrich the life on Earth).
Staff
 
 
National Institute of Biology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Department of Biotechnology and Systems Biology ,[object Object],[object Object],[object Object],[object Object],Pr. Dr Maja Ravnikar
- Horizontal project organisation: - OMICS (Kristina Gruden) - MICROBIOLOGY (Maja Ravnikar) - GENETICALY MODIFIED ORGANISMS (Jana Žel) - Infrastructure (Maruša Pompe Novak) - Quality Assurance and lab safety issues (Marjana Camloh) - Human resources and pedagogical activities (Maja Kovač, Marina Dermastia) - Bio-security (Mojca Milavec) Activities
Projects ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
International cooperation  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
OMICS: Systems biology approaches Methodologies ,[object Object],[object Object],[object Object],[object Object],[object Object]
OMICS: Systems biology approaches ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Biological   problems :
MICROBIOLOGY ,[object Object],[object Object],[object Object]
Real time RT- PCR: PVY NTN  - distinction of strains  CSNV, TSWV, INSV ToMV (CIM), CaMV (CIM), PePMV - distinction of strains,  Rotaviruses – water samples Xylophyllus ampelinus , Eam, Phytoplasmas Microarray technology, ring  trial New Methods: Development of sensitive methods for plant pathogen  detection
Concentration and purification of plant viruses ,[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],Genetically Modified Organisms (GMOs):
[object Object],[object Object],Transgenic plants
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Research and development, projects
GMOs diagnostics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
National Reference laboratory ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Studies, PhD
Studies, PhD ,[object Object],[object Object],[object Object],[object Object],[object Object],Poitiers University, France
[object Object],[object Object],[object Object],[object Object]
First postdoc
First postdoc Postdoctoral studies in University Laval and Hospital Laval, Quebec city, Qc, Canada ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Neutrophil inhibitors PDE4 inhibitors Alveolar repair Mucoregulators Immunosuppressants? Protease inhibitors  AAT, SLPI, pre-elafin, TIMPs Mediator antagonists LTB 4 inhibitors Chemokine antagonists Quit smoking Emphysema Mucus hypersecretion PROTEASES Neutrophil elastase Cathepsins MMPs Neutrophil Alveolar macrophage CD8 + lymphocyte Chemotactic mediators (IL-8, LTB 4 ) MCP-1 ?
Actual work ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Traceability issues  ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Actual work
Relation with authorities ,[object Object],[object Object],[object Object],[object Object],NATIONAL INSTITUTE OF  BIOLOGY Ministry of Health Ministry of Environment  and Spatial Planning Ministry of Agriculture, Forestry and Food Inspectorate for  Agriculture, Forestry and  Food Inspectorate for the  Environment and Spatial  Planning Health Inspectorate Ministry of Defence and  Slovenian Research Agency
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Actual work
National Reference laboratory ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Shanghai University

  • 1. Research: thoughts on a personal experience. Dany Morisset [email_address] http://www.nib.si/en/
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  • 3. Where is Slovenia? Shanghai Slovenia
  • 6. Slovenia (Slovenija) GENERAL INFORMATION Area: ............. ............. 20,273 km2 (80km x 260 km) 7,037km2 for Shanghai (city) Forest: .......... ............. 10,124 km2 (49.9%) Vineyards: ......... ......... 216 km2 Length of coast:..........46.6 km Capital: ........... ........... Ljubljana Population: ........ ... .....2 ,023,000 (2008) 18,450,000 in Shanghai (2007) Language: ........ ........ .Slovene Currency: ....... ....... ....Euro, 1 January 2007 Education: ........... ...... Universities in Ljubljana , Nova Gorica and Maribor cca 90,000 students
  • 7. Triglav, the highest Slovenian mountain Bled, jewel of the Julian Alps Ljubljana, the capital city Rafting on the Soča River
  • 8. Piran, Tartini’s coastal town Piran bay Julian Alps
  • 9. Postojna Cave Lipica horses Proteus anguinus or human fish Karstic land in Škocjan park
  • 10. Vineyard from Štajerska Region Slovenian specialities Slovenian wine producing
  • 11. National Institute of Biology at the Biological Centre in Ljubljana Italy Germany Venezzia (Venice)
  • 12. NIB is the leading institution for basic and applied research in biological sciences in Slovenia… and… the third largest institution in the field of natural sciences in Slovenia!
  • 13. Mission NIB is a public research institute, established by the Republic of Slovenia with the mission: - to create new (basic) knowledge on the field of biology and related natural sciences; - to transfer new knowledge into use for improvement of the quality of life (to enrich the life on Earth).
  • 14. Staff
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  • 19. - Horizontal project organisation: - OMICS (Kristina Gruden) - MICROBIOLOGY (Maja Ravnikar) - GENETICALY MODIFIED ORGANISMS (Jana Žel) - Infrastructure (Maruša Pompe Novak) - Quality Assurance and lab safety issues (Marjana Camloh) - Human resources and pedagogical activities (Maja Kovač, Marina Dermastia) - Bio-security (Mojca Milavec) Activities
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  • 25. Real time RT- PCR: PVY NTN - distinction of strains CSNV, TSWV, INSV ToMV (CIM), CaMV (CIM), PePMV - distinction of strains, Rotaviruses – water samples Xylophyllus ampelinus , Eam, Phytoplasmas Microarray technology, ring trial New Methods: Development of sensitive methods for plant pathogen detection
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