The document discusses crew fatigue management in airline operations. It describes how Jeppesen Crew Solutions manages fatigue for 250,000 crew members daily through crew planning and day-of-operations solutions. It also discusses flight and duty time limits (FTLs), fatigue risk management systems (FRMSs), fatigue models, and a tool called CrewAlert that collects fatigue data and issues reports to help align rules and scheduling with fatigue science. The goal is to transition to next generation rules and scheduling that better account for human factors like fatigue.