Seminar on carcinoma penis
•Download as PPTX, PDF•
4 likes•388 views
This seminar discusses carcinoma penis. Dr. A.I. Mazumder is the moderator and Dr. Biswajit Deka is the presenter. Carcinoma penis is uncommon but psychologically devastating when diagnosed. It is important to differentiate between benign, premalignant, and malignant conditions. Metastasis often occurs if diagnosis or treatment is delayed and can be lethal. The cancer typically spreads slowly at first and may not cause symptoms, allowing it to progress before being found.
Report
Share
Report
Share
Recommended
CARCINOMA PENIS
1) Cancers of the penis are rare but devastating, accounting for 0.4-0.6% of cancers in men in the US and Europe but up to 10% in some other regions.
2) Risk factors include poor hygiene, phimosis, HPV infection, and lack of circumcision. Over 95% are squamous cell carcinoma.
3) Staging involves physical exam, biopsy, and imaging of lymph nodes and distant organs. Treatment may include organ-sparing surgery or penile amputation depending on size, grade, and extent of invasion.
Carcinoma penis
This document summarizes carcinoma of the penis, including its risk factors, presentation, diagnosis, staging, treatment, and prognosis. It originates most commonly from the inner foreskin or glans in men around age 58. Over 90% of cases are squamous cell carcinoma (SCC). Risk factors include phimosis, HPV infection, smoking, and lack of circumcision. Diagnosis involves examination and biopsy. Staging uses the TNM system, with higher T and N stages associated with worse prognosis. Treatment aims to balance cancer control with quality of life impacts like sexual and urinary dysfunction. Prevention focuses on education, circumcision, HPV vaccination, and smoking cessation.
Prostate Cancer and Gleason Score
Understanding how the Gleason pattern score and grade group impact the outcome and treatment of prostate cancer
Carcinoma penis
It is a complete presentation on carcinoma penis, covering all aspects starting from premalignant lesions to details of squamous cell carcinoma penis including recent NCCN guidelines and steps of penectomy and lymph node dissection
Management of Non Muscle Invasive Bladder Cancer
Approach to non- muscle invasive bladder cancer and management .Details about Risk Stratification , TURBT & Intravesical Therapy.
Pathology of Endometrial cancer 2022.pptx
This is a concise presentation on the pathology of endometrial cancer based on the latest WHO female genital tumors latest edition, 5th edition
prepared on April 2022
Prostate carcinoma- pathology and staging
This document discusses the pathology and staging of prostatic neoplasia. It begins by classifying different types of prostate tumors, including adenocarcinoma, prostatic intraepithelial neoplasia (PIN), and other rare subtypes. It then focuses on PIN and adenocarcinoma, discussing their histological features, risk of associated malignancy, and clinical implications. The document also covers tumor grading using the Gleason scoring system, methods of tumor spread, prognostic factors, and considerations for various prostate tumor subtypes and treatments.
Bladder Cancer
Bladder cancer is the fourth most common cancer in men and seventh most common in women. 90-95% of cases are transitional-cell carcinoma. Standard treatment for superficial bladder cancer is transurethral resection followed by adjuvant intravesical therapy to reduce relapse rates by 30-80%. For invasive bladder cancer, radical cystectomy provides 5-year survival rates ranging from 77% for stage I to 12% for stage IV disease. Combined modality therapy with chemotherapy and radiotherapy can yield 5-year survival rates of 50-69% and organ preservation rates of 38-45% for invasive bladder cancer.
Recommended
CARCINOMA PENIS
1) Cancers of the penis are rare but devastating, accounting for 0.4-0.6% of cancers in men in the US and Europe but up to 10% in some other regions.
2) Risk factors include poor hygiene, phimosis, HPV infection, and lack of circumcision. Over 95% are squamous cell carcinoma.
3) Staging involves physical exam, biopsy, and imaging of lymph nodes and distant organs. Treatment may include organ-sparing surgery or penile amputation depending on size, grade, and extent of invasion.
Carcinoma penis
This document summarizes carcinoma of the penis, including its risk factors, presentation, diagnosis, staging, treatment, and prognosis. It originates most commonly from the inner foreskin or glans in men around age 58. Over 90% of cases are squamous cell carcinoma (SCC). Risk factors include phimosis, HPV infection, smoking, and lack of circumcision. Diagnosis involves examination and biopsy. Staging uses the TNM system, with higher T and N stages associated with worse prognosis. Treatment aims to balance cancer control with quality of life impacts like sexual and urinary dysfunction. Prevention focuses on education, circumcision, HPV vaccination, and smoking cessation.
Prostate Cancer and Gleason Score
Understanding how the Gleason pattern score and grade group impact the outcome and treatment of prostate cancer
Carcinoma penis
It is a complete presentation on carcinoma penis, covering all aspects starting from premalignant lesions to details of squamous cell carcinoma penis including recent NCCN guidelines and steps of penectomy and lymph node dissection
Management of Non Muscle Invasive Bladder Cancer
Approach to non- muscle invasive bladder cancer and management .Details about Risk Stratification , TURBT & Intravesical Therapy.
Pathology of Endometrial cancer 2022.pptx
This is a concise presentation on the pathology of endometrial cancer based on the latest WHO female genital tumors latest edition, 5th edition
prepared on April 2022
Prostate carcinoma- pathology and staging
This document discusses the pathology and staging of prostatic neoplasia. It begins by classifying different types of prostate tumors, including adenocarcinoma, prostatic intraepithelial neoplasia (PIN), and other rare subtypes. It then focuses on PIN and adenocarcinoma, discussing their histological features, risk of associated malignancy, and clinical implications. The document also covers tumor grading using the Gleason scoring system, methods of tumor spread, prognostic factors, and considerations for various prostate tumor subtypes and treatments.
Bladder Cancer
Bladder cancer is the fourth most common cancer in men and seventh most common in women. 90-95% of cases are transitional-cell carcinoma. Standard treatment for superficial bladder cancer is transurethral resection followed by adjuvant intravesical therapy to reduce relapse rates by 30-80%. For invasive bladder cancer, radical cystectomy provides 5-year survival rates ranging from 77% for stage I to 12% for stage IV disease. Combined modality therapy with chemotherapy and radiotherapy can yield 5-year survival rates of 50-69% and organ preservation rates of 38-45% for invasive bladder cancer.
Management of prostate cancer
Management of prostate cancer involves assessing risk levels based on PSA, Gleason score, and percentage of positive biopsy cores. Treatment options include active surveillance for low risk prostate cancer with potential delayed treatment if cancer progresses. Radical prostatectomy is the gold standard for localized prostate cancer and provides the possibility of cure with minimal side effects when performed by an experienced surgeon. While providing excellent cancer control, radical prostatectomy carries risks of erectile dysfunction and urinary incontinence.
TESTICULAR TUMOURS
Testicular tumours are divided into three main groups: germ cell tumours, sex cord-stromal tumours, and mixed forms. Germ cell tumours account for 95% of cases and are further classified as seminomas and non-seminomas. Seminomas and non-seminomas have distinct characteristics and prognoses. Common germ cell tumour subtypes include embryonal carcinoma, yolk sac tumour, choriocarcinoma, and teratoma. Tumour markers such as HCG and AFP help diagnose and monitor germ cell tumours. Mixed germ cell tumours contain more than one histologic type and typically have a worse prognosis.
Testicular tumours by dr abrar
This document discusses testicular tumours and their anatomy, etiology, classification, clinical features, diagnosis, staging, and treatment. Some key points:
- Testicular tumours most commonly occur in men ages 20-35 and risk factors include cryptorchidism, Klinefelter syndrome, and history of mumps orchitis.
- Germ cell tumours make up 90-95% of cases and include seminomas, teratomas, embryonal carcinomas, and others. Staging involves clinical exam, imaging, and tumour markers.
- Diagnosis involves ultrasound and biopsy of solid intratesticular masses. Treatment depends on tumour type, stage, and involves surgery, radiation,
Carcinoma penis
This document discusses carcinomas and precancerous conditions of the penis. It describes several precancerous conditions that have potential to develop into penile cancer, including penile intraepithelial neoplasia, balanitis xerotica obliterans, and Buschke-Lowenstein tumour. Squamous cell carcinoma is the most common type of penile cancer. Risk factors include age, pre-existing lesions, lack of circumcision, HPV infection, and smoking. Treatment involves surgery for the primary tumor as well as lymphadenectomy for lymph node involvement.
Ca penis
The document discusses carcinoma penis, including its epidemiology, risk factors, pathology, staging, investigations, and treatment options. Premalignant lesions like erythroplasia of Queyrat and balanitis xerotica obliterans are described. Treatment depends on the stage and includes circumcision for small tumors, local excision, glansectomy, Mohs micrographic surgery, and laser surgery to preserve the organ while wide local excision or penectomy may be needed for more advanced cases.
Testicular tumors-Cassification, Biomarkers and Staging by Dr Rajesh
This document discusses testicular tumors, including:
- Germ cell tumors are the most common type, comprising 95% of cases. Seminomas and non-seminomatous germ cell tumors are the main subtypes.
- Important biomarkers for testicular cancer include AFP, HCG, LDH, and PLAP. Elevated levels can indicate the presence of a non-seminoma.
- Staging is important and is based on whether the cancer is confined to the testis or has spread to lymph nodes or other organs. Spread beyond the retroperitoneum is considered stage III.
- Diagnostic workup involves imaging like ultrasound, CT, MRI and PET scans
Pathology of Prostate - Cancer
Prostate cancer is the most common cancer in men. While some prostate cancers are small and clinically insignificant, others can be rapidly fatal. The percentage of free PSA to total PSA is lower in men with prostate cancer. Microscopically, prostate cancer shows pleomorphic cells in single layer glands without secretions, unlike the normal double layer glands. Gleason scoring is used to grade prostate cancers from 1 to 10 based on their appearance under microscopy. Staging helps determine prognosis, with stage 1 having a 90% 5-year survival rate compared to 10% for stage 4 cancers.
Carcinoma penis
Ca penis - Introduction with incidence, risk factors, pre malignant conditions, staging, investigation, and management.
CARCINOMA PROSTATE- Dr Manoj Kumar B, PGI
The document discusses carcinoma of the prostate, including its anatomy, epidemiology, etiology, natural history, clinical manifestations, diagnostic workup, imaging, and management. It provides detailed information on prostate anatomy, risk factors for prostate cancer, methods of evaluation including PSA levels, biopsy, and various imaging modalities like ultrasound, CT, and MRI.
CA Prostate
The document discusses the anatomy and diagnostic evaluation of prostate cancer. It describes the prostate as a walnut-sized gland located below the bladder and surrounding the urethra. The primary function is to produce seminal fluid. Diagnostic workup involves PSA levels, digital rectal exam, prostate biopsy and various imaging modalities like CT, MRI, bone scan and PSMA PET/CT to stage disease extent and metastasis. Gleason scoring is used to grade prostate cancer based on architectural patterns seen on biopsy.
Testicular tumours
Testicular tumors are rare.
1 – 2 % of all malignant tumors.
Most common malignancy in men in the 15 to 35 year age group.
Benign lesions represent a greater percentage of cases in children than in adults.
Most curable solid neoplasm
Ovarian tumors by mahmoud kareem
This document discusses ovarian tumors. It notes that ovarian tumors can be cystic or solid, functional, benign or malignant. In reproductive-aged women, most ovarian enlargements are functional cysts, while 25% prove to be nonfunctional neoplasms of which 90% are benign. Ovarian masses in postmenopausal patients or those unresponsive to birth control present a higher risk of malignancy. Evaluation involves examination and imaging like ultrasound. Common benign ovarian tumors include serous cystadenomas, mucinous cystadenomas, dermoid cysts, and granulosa cell tumors. Complications can include torsion, rupture, hemorrhage, and infection. Ovarian cancer is the fifth most common cancer in
Sumit testicular tumors
This document provides an overview of testicular cancer, including:
1. Testicular cancer most commonly affects men aged 20-40 and is the most common cancer in that age group. It has very good survival rates due to effective diagnostic techniques, tumor markers, and multimodal treatments.
2. Risk factors include cryptorchidism, Klinefelter syndrome, trauma, and genetic factors. Cryptorchidism increases risk by 14-48 times.
3. Types include seminomas, embryonal carcinomas, teratomas, and others. Seminomas and non-seminomas are treated differently.
4. Diagnosis involves physical exam, ultrasound, tumor markers like AFP and H
Testicular tumors
This document provides information on testicular tumors, including:
1. It describes the two major categories of testicular tumors - germ cell tumors (95% of cases) and sex cord-stromal tumors. Germ cell tumors are aggressive cancers capable of rapid dissemination but most can now be cured.
2. It covers the various types of germ cell tumors - seminoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, and teratoma - discussing their characteristics, risk factors, pathogenesis, morphology, and microscopy.
3. Seminoma is the most common germ cell tumor, occurring most often in the third decade. Embryonal carcinoma is more
Non melanoma skin cancers
Squamous cell carcinoma and basal cell carcinoma are the two most common types of non-melanoma skin cancer. Squamous cell carcinoma occurs more often in sun-exposed areas and affects men more than women. Larger lesions, deeper invasion and higher grades are associated with greater recurrence risk. Treatment options include excision, cryotherapy and radiation therapy. Basal cell carcinoma is more common and occurs predominantly in light-skinned individuals on sun-exposed areas. The nodular type is most common. Treatment involves wide local excision, Mohs surgery, or radiation therapy depending on size and location.
Testicular Cancer
This document provides information on testicular cancer, including its incidence, histology, lymph node drainage patterns, staging classifications, workup, and management guidelines. Some key points:
- Testicular cancers constitute 1% of all cancers and germ cell tumors are the most common solid tumors in men aged 15-35.
- Lymph node drainage patterns differ for right and left testes, with retroperitoneal lymph nodes being the most common site of spread.
- Germ cell tumors are the most common type and are classified based on their histologic components.
- Staging involves the TNM classification and serum tumor marker levels. Workup includes imaging, tumor marker tests, and radical orchi
Germ cell tumors of ovary
Presentation about the the second most common type of ovarian tumors which have a very unique property of being similar to the testicular germ cell tumors.
Pathology ca bladder
FOLLOW THE YOU TUBE CHANNEL FOR FUTURE UROLOGY VIDEO
https://www.youtube.com/channel/UCINcUe475Y3c3BvXHvZ8wEw
Renal cell carcinoma
Three doctors presented on renal cell carcinoma. Some key points:
- Renal cell carcinoma arises from renal tubular cells and is the most common type of kidney cancer.
- Presentation may include hematuria, loin pain, and palpable abdominal mass. Metastasis can cause cough or bone pain.
- Diagnosis involves imaging like CT scan and lab tests. Surgery is the main treatment but immunotherapy and targeted drugs are also used.
- Prognosis depends on stage - early stage has good prognosis but late stage with metastasis has poorer outlook.
pranaya ppt Management of nsgct
This document discusses testicular cancer, including:
- Risk factors include history of undescended testes, contralateral testicular tumor, or Klinefelter syndrome.
- Tumors are classified as germ cell tumors (most common), interstitial cell tumors, lymphoma, or other rare tumors.
- Seminoma and non-seminomatous germ cell tumors (NSGCT) are the main types of germ cell tumors.
- Diagnostic workup includes scrotal ultrasound, serum tumor markers, chest imaging and lymph node assessment to determine clinical stage according to the TNM system.
Testicular tumors
This document provides information about testicular tumors including presentation, risk factors, classification, staging, and treatment. It begins with an introduction stating that testicular cancer is the most common malignancy in males aged 15-35. It then discusses signs and symptoms, risk factors such as cryptorchidism and family history, tumor markers, patterns of spread, staging classifications, and treatment options based on stage for both seminomas and non-seminomas. Treatment may involve surgery, radiation therapy, chemotherapy, lymph node dissection, and surveillance depending on tumor type and stage. Prognosis has improved significantly over time with overall 5-year survival rates now over 95% due to advances in diagnosis and treatment.
Mediastinal Mass dr dharma poonia
1) Mediastinal masses can occur in the three compartments of the mediastinum and are diverse in pathology. 2) CT is usually the initial imaging modality of choice to determine the location and characteristics of the mass. 3) Tissue biopsy is often required before treatment planning to determine the specific diagnosis, as the approach depends on factors such as location, imaging features, and patient age.
More Related Content
What's hot
Management of prostate cancer
Management of prostate cancer involves assessing risk levels based on PSA, Gleason score, and percentage of positive biopsy cores. Treatment options include active surveillance for low risk prostate cancer with potential delayed treatment if cancer progresses. Radical prostatectomy is the gold standard for localized prostate cancer and provides the possibility of cure with minimal side effects when performed by an experienced surgeon. While providing excellent cancer control, radical prostatectomy carries risks of erectile dysfunction and urinary incontinence.
TESTICULAR TUMOURS
Testicular tumours are divided into three main groups: germ cell tumours, sex cord-stromal tumours, and mixed forms. Germ cell tumours account for 95% of cases and are further classified as seminomas and non-seminomas. Seminomas and non-seminomas have distinct characteristics and prognoses. Common germ cell tumour subtypes include embryonal carcinoma, yolk sac tumour, choriocarcinoma, and teratoma. Tumour markers such as HCG and AFP help diagnose and monitor germ cell tumours. Mixed germ cell tumours contain more than one histologic type and typically have a worse prognosis.
Testicular tumours by dr abrar
This document discusses testicular tumours and their anatomy, etiology, classification, clinical features, diagnosis, staging, and treatment. Some key points:
- Testicular tumours most commonly occur in men ages 20-35 and risk factors include cryptorchidism, Klinefelter syndrome, and history of mumps orchitis.
- Germ cell tumours make up 90-95% of cases and include seminomas, teratomas, embryonal carcinomas, and others. Staging involves clinical exam, imaging, and tumour markers.
- Diagnosis involves ultrasound and biopsy of solid intratesticular masses. Treatment depends on tumour type, stage, and involves surgery, radiation,
Carcinoma penis
This document discusses carcinomas and precancerous conditions of the penis. It describes several precancerous conditions that have potential to develop into penile cancer, including penile intraepithelial neoplasia, balanitis xerotica obliterans, and Buschke-Lowenstein tumour. Squamous cell carcinoma is the most common type of penile cancer. Risk factors include age, pre-existing lesions, lack of circumcision, HPV infection, and smoking. Treatment involves surgery for the primary tumor as well as lymphadenectomy for lymph node involvement.
Ca penis
The document discusses carcinoma penis, including its epidemiology, risk factors, pathology, staging, investigations, and treatment options. Premalignant lesions like erythroplasia of Queyrat and balanitis xerotica obliterans are described. Treatment depends on the stage and includes circumcision for small tumors, local excision, glansectomy, Mohs micrographic surgery, and laser surgery to preserve the organ while wide local excision or penectomy may be needed for more advanced cases.
Testicular tumors-Cassification, Biomarkers and Staging by Dr Rajesh
This document discusses testicular tumors, including:
- Germ cell tumors are the most common type, comprising 95% of cases. Seminomas and non-seminomatous germ cell tumors are the main subtypes.
- Important biomarkers for testicular cancer include AFP, HCG, LDH, and PLAP. Elevated levels can indicate the presence of a non-seminoma.
- Staging is important and is based on whether the cancer is confined to the testis or has spread to lymph nodes or other organs. Spread beyond the retroperitoneum is considered stage III.
- Diagnostic workup involves imaging like ultrasound, CT, MRI and PET scans
Pathology of Prostate - Cancer
Prostate cancer is the most common cancer in men. While some prostate cancers are small and clinically insignificant, others can be rapidly fatal. The percentage of free PSA to total PSA is lower in men with prostate cancer. Microscopically, prostate cancer shows pleomorphic cells in single layer glands without secretions, unlike the normal double layer glands. Gleason scoring is used to grade prostate cancers from 1 to 10 based on their appearance under microscopy. Staging helps determine prognosis, with stage 1 having a 90% 5-year survival rate compared to 10% for stage 4 cancers.
Carcinoma penis
Ca penis - Introduction with incidence, risk factors, pre malignant conditions, staging, investigation, and management.
CARCINOMA PROSTATE- Dr Manoj Kumar B, PGI
The document discusses carcinoma of the prostate, including its anatomy, epidemiology, etiology, natural history, clinical manifestations, diagnostic workup, imaging, and management. It provides detailed information on prostate anatomy, risk factors for prostate cancer, methods of evaluation including PSA levels, biopsy, and various imaging modalities like ultrasound, CT, and MRI.
CA Prostate
The document discusses the anatomy and diagnostic evaluation of prostate cancer. It describes the prostate as a walnut-sized gland located below the bladder and surrounding the urethra. The primary function is to produce seminal fluid. Diagnostic workup involves PSA levels, digital rectal exam, prostate biopsy and various imaging modalities like CT, MRI, bone scan and PSMA PET/CT to stage disease extent and metastasis. Gleason scoring is used to grade prostate cancer based on architectural patterns seen on biopsy.
Testicular tumours
Testicular tumors are rare.
1 – 2 % of all malignant tumors.
Most common malignancy in men in the 15 to 35 year age group.
Benign lesions represent a greater percentage of cases in children than in adults.
Most curable solid neoplasm
Ovarian tumors by mahmoud kareem
This document discusses ovarian tumors. It notes that ovarian tumors can be cystic or solid, functional, benign or malignant. In reproductive-aged women, most ovarian enlargements are functional cysts, while 25% prove to be nonfunctional neoplasms of which 90% are benign. Ovarian masses in postmenopausal patients or those unresponsive to birth control present a higher risk of malignancy. Evaluation involves examination and imaging like ultrasound. Common benign ovarian tumors include serous cystadenomas, mucinous cystadenomas, dermoid cysts, and granulosa cell tumors. Complications can include torsion, rupture, hemorrhage, and infection. Ovarian cancer is the fifth most common cancer in
Sumit testicular tumors
This document provides an overview of testicular cancer, including:
1. Testicular cancer most commonly affects men aged 20-40 and is the most common cancer in that age group. It has very good survival rates due to effective diagnostic techniques, tumor markers, and multimodal treatments.
2. Risk factors include cryptorchidism, Klinefelter syndrome, trauma, and genetic factors. Cryptorchidism increases risk by 14-48 times.
3. Types include seminomas, embryonal carcinomas, teratomas, and others. Seminomas and non-seminomas are treated differently.
4. Diagnosis involves physical exam, ultrasound, tumor markers like AFP and H
Testicular tumors
This document provides information on testicular tumors, including:
1. It describes the two major categories of testicular tumors - germ cell tumors (95% of cases) and sex cord-stromal tumors. Germ cell tumors are aggressive cancers capable of rapid dissemination but most can now be cured.
2. It covers the various types of germ cell tumors - seminoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, and teratoma - discussing their characteristics, risk factors, pathogenesis, morphology, and microscopy.
3. Seminoma is the most common germ cell tumor, occurring most often in the third decade. Embryonal carcinoma is more
Non melanoma skin cancers
Squamous cell carcinoma and basal cell carcinoma are the two most common types of non-melanoma skin cancer. Squamous cell carcinoma occurs more often in sun-exposed areas and affects men more than women. Larger lesions, deeper invasion and higher grades are associated with greater recurrence risk. Treatment options include excision, cryotherapy and radiation therapy. Basal cell carcinoma is more common and occurs predominantly in light-skinned individuals on sun-exposed areas. The nodular type is most common. Treatment involves wide local excision, Mohs surgery, or radiation therapy depending on size and location.
Testicular Cancer
This document provides information on testicular cancer, including its incidence, histology, lymph node drainage patterns, staging classifications, workup, and management guidelines. Some key points:
- Testicular cancers constitute 1% of all cancers and germ cell tumors are the most common solid tumors in men aged 15-35.
- Lymph node drainage patterns differ for right and left testes, with retroperitoneal lymph nodes being the most common site of spread.
- Germ cell tumors are the most common type and are classified based on their histologic components.
- Staging involves the TNM classification and serum tumor marker levels. Workup includes imaging, tumor marker tests, and radical orchi
Germ cell tumors of ovary
Presentation about the the second most common type of ovarian tumors which have a very unique property of being similar to the testicular germ cell tumors.
Pathology ca bladder
FOLLOW THE YOU TUBE CHANNEL FOR FUTURE UROLOGY VIDEO
https://www.youtube.com/channel/UCINcUe475Y3c3BvXHvZ8wEw
Renal cell carcinoma
Three doctors presented on renal cell carcinoma. Some key points:
- Renal cell carcinoma arises from renal tubular cells and is the most common type of kidney cancer.
- Presentation may include hematuria, loin pain, and palpable abdominal mass. Metastasis can cause cough or bone pain.
- Diagnosis involves imaging like CT scan and lab tests. Surgery is the main treatment but immunotherapy and targeted drugs are also used.
- Prognosis depends on stage - early stage has good prognosis but late stage with metastasis has poorer outlook.
pranaya ppt Management of nsgct
This document discusses testicular cancer, including:
- Risk factors include history of undescended testes, contralateral testicular tumor, or Klinefelter syndrome.
- Tumors are classified as germ cell tumors (most common), interstitial cell tumors, lymphoma, or other rare tumors.
- Seminoma and non-seminomatous germ cell tumors (NSGCT) are the main types of germ cell tumors.
- Diagnostic workup includes scrotal ultrasound, serum tumor markers, chest imaging and lymph node assessment to determine clinical stage according to the TNM system.
What's hot (20)
Testicular tumors-Cassification, Biomarkers and Staging by Dr Rajesh
Testicular tumors-Cassification, Biomarkers and Staging by Dr Rajesh
Similar to Seminar on carcinoma penis
Testicular tumors
This document provides information about testicular tumors including presentation, risk factors, classification, staging, and treatment. It begins with an introduction stating that testicular cancer is the most common malignancy in males aged 15-35. It then discusses signs and symptoms, risk factors such as cryptorchidism and family history, tumor markers, patterns of spread, staging classifications, and treatment options based on stage for both seminomas and non-seminomas. Treatment may involve surgery, radiation therapy, chemotherapy, lymph node dissection, and surveillance depending on tumor type and stage. Prognosis has improved significantly over time with overall 5-year survival rates now over 95% due to advances in diagnosis and treatment.
Mediastinal Mass dr dharma poonia
1) Mediastinal masses can occur in the three compartments of the mediastinum and are diverse in pathology. 2) CT is usually the initial imaging modality of choice to determine the location and characteristics of the mass. 3) Tissue biopsy is often required before treatment planning to determine the specific diagnosis, as the approach depends on factors such as location, imaging features, and patient age.
Ca thyroid
Thyroid cancers can affect the follicular or parafollicular cells of the thyroid gland. The most common types are papillary carcinoma, follicular carcinoma, and medullary carcinoma. Risk factors include genetics, family history, radiation exposure, and iodine deficiency. Symptoms may include thyroid nodules, neck lymphadenopathy, or changes in voice. Diagnosis involves blood tests, ultrasound, biopsy, and imaging. Treatment depends on cancer type and severity but commonly includes surgery followed by radiation or other therapies. Prognosis depends on factors like cancer stage, size, and spread.
Urologic malignancy
UROLOGY RENAL CANCER PENIS TESTICULAR CANCER PENILE CANCER BLADDER CANCER KIDNEY CANCER PROSTATE CANCER
Thyroid ca
1) Thyroid cancer is the most common endocrine malignancy, with papillary carcinoma being the most prevalent histological type.
2) Differentiated thyroid cancers originate from follicular epithelial cells and include papillary, follicular, and Hurthle cell carcinomas.
3) Risk factors include prior radiation exposure, family history of thyroid cancer, and certain genetic mutations. Evaluation involves ultrasound, biopsy, and staging.
4) Prognosis is generally good, though it varies by cancer type, stage, and other factors. Treatment involves surgery, radioiodine ablation, and other therapies.
Pancreatic tumours.ppt.pptx
The document discusses pancreatic neoplasms, including mucinous cystic neoplasm of the pancreas with liver and lymph node metastases. Key details include that mucinous cystic neoplasms are premalignant tumors exclusively seen in women, typically located in the pancreas tail or body. Imaging findings on CT and MRI are described. The document also discusses pancreatic adenocarcinoma, neuroendocrine tumors, cystic neoplasms such as IPMN and SCN, and considerations for determining resectability of pancreatic tumors based on vascular involvement.
Hepatocellular carcinoma
Hepatocellular carcinoma is the most common primary liver tumor. Risk factors include hepatitis B and C infections, alcohol use, and exposure to aflatoxins. It typically presents with nonspecific symptoms in patients with underlying liver disease or cirrhosis. Diagnosis involves blood tests like alpha-fetoprotein along with imaging modalities. Treatment options depend on tumor stage and liver function, and may include surgical resection, liver transplantation, ablation, or chemoembolization. Prevention focuses on hepatitis B vaccination and screening high-risk groups to detect cancer early.
Seminar ca penis
1) Carcinoma of the penis has a higher incidence in South America, East Africa, and South East Asia. Risk factors include HPV infection, phimosis, smoking, and lack of circumcision.
2) Early stage lesions include erythroplasia of Queyrat, Bowen's disease, balanitis xerotica obliterans, and giant condyloma acuminatum. Advanced lesions are staged using the TNM system.
3) Treatment depends on the stage but may include local excision, circumcision, partial or total penectomy. Sentinel lymph node biopsy helps determine if inguinal lymphadenectomy is needed.
Thyroid carcinoma
This document provides information on lymph node levels and classification of thyroid neoplasms. It describes the six levels of cervical lymph nodes and discusses papillary carcinoma and follicular carcinoma of the thyroid in detail. For papillary carcinoma, it covers presentation, histology, prognosis, treatment including surgery and radioactive iodine therapy. For follicular carcinoma, it discusses presentation, spread, histology and treatment. It also briefly summarizes other malignant thyroid tumors including medullary carcinoma, anaplastic carcinoma and thyroid lymphoma.
Soft tissue sarcomas
This document summarizes soft tissue sarcomas (STS), a rare type of cancer. It discusses that STS can occur anywhere in the body and there are over 100 subtypes. Surgery is the main treatment but chemotherapy and radiation therapy may also be used. Prognosis depends on factors like tumor size, grade, and whether it has metastasized. Recurrence is common and occurs in up to 50% of cases. Specific types discussed include gastrointestinal stromal tumor (GIST) and retroperitoneal sarcomas, which have poorer outcomes compared to extremity STS. Liposarcoma and leiomyosarcoma are two of the most common STS subtypes.
Diagnosis & treatment for salivary gland tumours
1. Salivary gland neoplasms are relatively rare, accounting for 6% of head and neck tumors, with parotid gland tumors making up 80% of cases.
2. Clinical presentation depends on whether the tumor is benign or malignant. Benign tumors usually present as asymptomatic swellings while malignant tumors can present with pain, nerve palsies, or nodal metastases.
3. Diagnosis involves investigations like ultrasound, CT, MRI and biopsy to determine the nature and extent of the tumor. However, differentiating between benign and malignant, and identifying the exact histology can still be challenging.
(MALIGNANT) MELANOMA- PPT
This document discusses melanoma, a type of skin cancer that arises from pigment cells. It begins with an introduction and case presentation of a 51-year-old male diagnosed with melanoma on his foot. It then covers the history, epidemiology, risk factors, pathogenesis, classification, diagnosis, staging, differential diagnosis, treatment, complications, prognosis, prevention, and follow-up of melanoma. Local experience at the author's hospital is also discussed. The conclusion emphasizes the importance of early diagnosis and treatment for a good prognosis with this type of cancer.
Cancer of PENIS by KUTOSI Joseph.pptx
This document summarizes penile cancer, including its anatomy, functions, risk factors, diagnosis, staging, and treatment options. It begins with an overview of the penis' anatomy and functions in the male reproductive and urinary systems. It then discusses risk factors for penile cancer like phimosis and HPV infection. Diagnosis involves biopsy and imaging to stage the cancer. Treatment depends on cancer stage but may include surgery, radiation, chemotherapy, or a combination in order to cure the cancer while preserving penis function and appearance. Prognosis depends on presence of lymph node metastases, with survival rates over 80% if few nodes are involved.
Ca esophagus 12th
This document provides information on carcinoma of the esophagus, including:
- Esophageal cancer is the 8th most common cancer worldwide, with high incidence rates in parts of Africa and Asia. Squamous cell carcinoma and adenocarcinoma account for most cases.
- The esophagus has three layers - mucosa, submucosa, and muscularis propria. It lacks a serosa, allowing early extraesophageal spread.
- Staging uses AJCC TNM and other systems to assess tumor size, lymph node involvement, and metastasis.
- Risk factors include smoking, alcohol, hot foods/liquids, micronutrient deficiencies, GERD, and Barrett's
solitarythyroidnodule-1904200227 by professor Dr Ahmed Al Abbasi52 [Autosaved...
- Solitary thyroid nodules are more common in women than men and occur in about 4-19% of the population depending on the method of detection. Fine-needle aspiration cytology (FNAC) is the most important diagnostic tool for evaluating thyroid nodules and can differentiate between benign and malignant nodules with over 90% accuracy. Ultrasonography is also useful for evaluating nodule characteristics that may indicate malignancy such as hypoechogenicity, microcalcifications, and irregular shapes. A combination of FNAC, ultrasound, and sometimes thyroid scans can accurately evaluate thyroid nodules in most cases.
Testicular tumor
This document provides information about testicular tumor (pure seminoma). It discusses that germ cell tumors account for 95% of malignant testicular tumors. Seminomas make up 40% of germ cell tumors and include classical, anaplastic, and spermatocytic subtypes. Staging and treatment options are provided for different stages of seminoma, including surveillance, radiotherapy, or chemotherapy. Follow up protocols depend on the initial treatment and involve tumor marker monitoring and imaging. Outcomes for stage I seminoma with standard treatment are over 99% disease-specific survival.
Carcinoma of esophagus
This document discusses esophageal cancer, including:
- It remains the 6th most common malignancy and rates vary globally. Squamous cell carcinoma is most common.
- Risk factors include smoking, alcohol, hot liquids and micronutrient deficiencies. Barrett's esophagus increases adenocarcinoma risk.
- Symptoms depend on location and stage but include dysphagia, weight loss, pain and cough.
- Diagnostic tools include endoscopy, CT, PET, MRI and EUS to determine stage.
- Treatment involves chemotherapy, radiation, and surgery depending on location and stage. Surgical techniques include transhiatal, Ivor Lewis and minimally invasive approaches.
Thyroid cancers
Thyroid cancers are infrequent but benign thyroid diseases are common. Papillary carcinoma is the most common type at 80% of cases. Women are three times more likely to be affected than men, with peak incidence between 30-40 years of age. Risk factors include radiation exposure and Hashimoto's thyroiditis. Fine needle aspiration cytology is the initial test to differentiate malignant from benign nodules. Total thyroidectomy with lymph node dissection is the main treatment for differentiated thyroid cancers. Long term thyroid hormone suppression therapy and monitoring of thyroglobulin levels and scans are important after surgery.
Testicular carcinoma
This document provides a summary of testicular carcinoma and germ cell tumors. It discusses the classification, spread, clinical features, investigations, and staging of testicular tumors. The majority are germ cell tumors, with seminomas and non-seminomatous germ cell tumors being the most common. Metastatic sites vary between seminomas and non-seminomas. Prognostic factors are important for determining treatment. Screening is recommended for high risk groups to detect tumors early.
Testicular tumour/ case history
1. Testicular neoplasm is a rare malignancy that affects men aged 20-40 years old. It presents most commonly as a painless testicular mass.
2. Diagnostic workup includes physical exam, tumor markers, imaging, and biopsy. Seminomas and nonseminomas are the two main types and have different characteristics and treatment approaches.
3. Treatment depends on stage but may include surgery, chemotherapy, and radiation. The prognosis is generally good even for advanced or relapsed disease.
Similar to Seminar on carcinoma penis (20)
Diagnosis & treatment for salivary gland tumours
Diagnosis & treatment for salivary gland tumours
solitarythyroidnodule-1904200227 by professor Dr Ahmed Al Abbasi52 [Autosaved...
solitarythyroidnodule-1904200227 by professor Dr Ahmed Al Abbasi52 [Autosaved...
More from Biswajit Deka
Endoluminal therapy in GERD
Dr. Biswajit Deka presented on endoluminal treatments for GERD. He discussed the pathophysiology of GERD and how endoluminal procedures aim to increase LES tone and length to prevent reflux. The main endoluminal procedures covered were EsophyX which creates an incisionless fundoplication, Stretta which uses RF to remodel the LES, MUSE which creates a partial fundoplication with staples, and injections or mucosal excision techniques. Complications were generally minor but include bleeding, perforation, and pain. Endoluminal GERD treatments are promising but still developing compared to anti-reflux
operations of Carcinoma rectum
The document discusses various surgical procedures for treating cancer of the rectum, including:
1. Abdomino-Perineal Resection (APR), the classic operation pioneered by Miles, which removes the rectum and anus through an abdominal and perineal approach.
2. Anterior Resection, which removes the rectum and part of the sigmoid colon and performs a colorectal or coloanal anastomosis.
3. Local excision techniques like Transanal Endoscopic Microsurgery (TEM) for early-stage or palliative cases.
4. Other procedures mentioned include Hartman's operation (resection with end colostomy), pelvic exenter
seminar on new technologies of cell and molecular biology
This document discusses new technologies in cell and molecular biology. It provides an overview of molecular biology and its history. Current applications include understanding disease pathophysiology, diagnosis, transplantation, gene therapy, and drug design. Molecular imaging techniques like PET, SPECT, MRI, ultrasound, and optical imaging allow non-invasive characterization of key biomolecules and events in vivo. These techniques can be used for diagnostic, therapeutic, and surgical applications by targeting specific molecules with molecular probes. Advances in targeted contrast agents are improving detection and visualization of diseases at the molecular level.
Seminar on choledochal cyst
This document summarizes a seminar on choledochal cysts. It discusses the presentation, incidence, classification, investigations, complications and management of choledochal cysts. The key points are:
1. Choledochal cysts are bile duct abnormalities that can occur anywhere in the biliary tree. Complete excision of extrahepatic cysts is the standard treatment.
2. They are most common in children but can sometimes be diagnosed in adults. Complications include biliary stones, pancreatitis and malignancy.
3. Investigations include ultrasound, CT, MRCP and ERCP to characterize the cyst type and rule out complications. Surgical excision and Roux-en
Seminar surgical oncology
1. The seminar discussed the basics of surgical oncology including the features of malignant transformation and the roles of surgery in cancer treatment such as prevention, diagnosis and staging, removing cancer, and relieving symptoms.
2. Different types of surgeries were covered like curative surgery, palliative surgery, debulking surgery, and preventive surgery. Tumor ablation techniques using energy such as radiofrequency and laser ablation were also summarized.
3. Newer surgical techniques in cancer treatment including laparoscopic surgery, robotics, cryosurgery, electrocautery, and microscopically controlled surgery were presented.
seminar Median nerve injury
This document summarizes a seminar on median nerve injury. It begins with an anatomy overview of peripheral nerves, brachial plexus, and the median nerve. It then discusses causes of median nerve injury including trauma, leprosy, poliomyelitis, and carpal tunnel syndrome. Symptoms and examination findings of median nerve injury and carpal tunnel syndrome are provided. The document concludes with an overview of nerve repair techniques including epineural repair, interfascicular repair, and nerve grafting.
Seminar on Hydrocephalus
This document summarizes a seminar presentation on hydrocephalus. It defines hydrocephalus as an increase in CSF volume with ventricular enlargement. It describes the physiology of CSF circulation and different types of hydrocephalus including obstructive, communicating, congenital and acquired. Clinical presentations and investigations are discussed. Treatment options include temporary external ventricular drainage, VP shunt placement, and endoscopic third ventriculostomy. Complications of shunt surgery and new treatment modalities are also summarized.
Seminar on stamm, janeway & PE gastrostomy
This document summarizes different techniques for gastrostomy tube placement: Stamm gastrostomy is a temporary procedure where a purse string suture is used to create a gastric opening for a catheter. Janeway gastrostomy is permanent, creating a gastric flap that is brought through the abdominal wall. Percutaneous endoscopic gastrostomy (PEG) involves passing a catheter through the stomach and abdominal wall under endoscopic guidance using a gastroscope, needle, snare, and suture.
seminar on Physiologic study
The document summarizes various physiologic tests that can be used to assess pelvic floor and anorectal disorders. It describes tests such as manometry, defecography, anal ultrasound, and tests of transit time. For each test, it provides details on the technique, indications for use, preparation, interpretation of results, and how the tests can help diagnose conditions like incontinence, constipation, and pain. The tests provide objective measures that can confirm diagnoses and evaluate treatments. When used together, the tests provide complementary information to fully assess pelvic floor and bowel function.
seminar on Leg swelling & its causes
This document summarizes leg swelling (edema) and its various causes. It begins by defining edema and mechanisms that can cause it like increased capillary permeability or pressure. It then categorizes causes of edema as either central (bilateral) or local (unilateral). Specific conditions that can lead to edema like cardiac failure, nephrotic syndrome, filariasis, and deep vein thrombosis are described. The document provides details on clinical presentations and risk factors for different types of edema.
seminar on Blood transfusion
The document summarizes a seminar on blood transfusion presented by Dr. Biswajit Deka. It discusses the history of blood transfusion and developments like blood grouping. It describes different blood components like packed red cells, platelets, fresh frozen plasma, and cryoprecipitate. The key steps for safe transfusion are donor selection, recipient blood grouping, cross-matching, and screening blood for infections. Common infections that can be transmitted through transfusion include HIV, hepatitis B, hepatitis C, syphilis, and parasites. Laboratory tests for detection of these infections are also outlined.
Physiologic study
This seminar discusses various physiologic tests used to assess pelvic floor and anorectal disorders, including manometry, defecography, anal ultrasound, MRI, and EMG. Manometry measures anorectal pressures and reflexes and can diagnose sphincter defects, constipation, and pain syndromes. Defecography evaluates anorectal anatomy and function during defecation. Anal ultrasound and MRI identify anatomical abnormalities of the anal sphincters. EMG assesses the integrity of the anal sphincter muscle and its nerve supply. These tests provide objective data to diagnose disorders and monitor treatments like biofeedback or surgery.
Median nerve injury
This document summarizes a seminar on median nerve injury. It begins with an anatomy overview of peripheral nerves, brachial plexus, and the median nerve. It then discusses causes of median nerve injury including trauma, leprosy, poliomyelitis, and carpal tunnel syndrome. Symptoms and examination findings of median nerve injury and carpal tunnel syndrome are provided. The document concludes with an overview of nerve repair techniques including epineural repair, interfascicular repair, and nerve grafting.
Surgical anatomy of hepatobiliary system by biswajit deka
This document summarizes a seminar on the surgical anatomy of the hepatobiliary system. It begins with an introduction to the liver, gallbladder, and biliary tree. It then discusses the historical background and some key figures. It provides facts about the liver and discusses its embryology and potential congenital anomalies. The remainder of the document details the gross anatomy of the liver including its lobes, ligaments, surfaces, and vascular structures. It then discusses the gallbladder, cystic duct, common bile duct, and variations. It concludes with the functions of the liver and biliary tree.
ZES
- Zollinger-Ellison Syndrome (ZES) is caused by gastrin-secreting tumors called gastrinomas that result in excessive stomach acid production.
- Gastrinomas most commonly occur in the pancreas or duodenum. ZES presents with severe peptic ulcers or acid-induced diarrhea and is diagnosed through blood tests showing high gastrin levels and low stomach pH.
- Treatment involves high-dose proton pump inhibitors, surgery to remove the gastrinoma, or highly selective vagotomy. Surgical removal of gastrinomas aims to cure ZES but can be challenging as tumors are sometimes small and multiple.
Hydrocephalus
seminar on hydrocephalus
reference : Bailey & love's short practice of surgery and Sabiston textbook of surgery
Seminar on basic principles of endovascular surgery
- Endovascular surgery uses catheter-guided devices to restore blood flow in occluded vessels by delivering thrombolytic agents directly to clots or removing clots mechanically.
- The technique was pioneered in the 1950s-1980s through developments like the Seldinger technique for arterial access using guidewires, methods for extracting thrombus using balloon catheters, and introducing balloon angioplasty and stents.
- Key devices used in endovascular procedures include guidewires, catheters, balloons, stents, and stent grafts, each with characteristics suited to their purpose like accessing vessels, delivering thrombolytic agents, dilating stenoses, scaffolding vessels, and excluding aneurys
More from Biswajit Deka (17)
seminar on new technologies of cell and molecular biology
seminar on new technologies of cell and molecular biology
Surgical anatomy of hepatobiliary system by biswajit deka
Surgical anatomy of hepatobiliary system by biswajit deka
Seminar on basic principles of endovascular surgery
Seminar on basic principles of endovascular surgery
Recently uploaded
Role of Mukta Pishti in the Management of Hyperthyroidism
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.Histololgy of Female Reproductive System.pptx
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Adhd Medication Shortage Uk - trinexpharmacy.com
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...rightmanforbloodline
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.The Best Ayurvedic Antacid Tablets in India
Treat the symptoms of indigestion, heartburn and stomach reflux with the 10 Best Ayurvedic Antacid Tablets in India.
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
Do you have abnormal smell after periods? It may be vaginitis. Do not worry, herbal medicine Fuyan Pill can help you get a cure.
Best Ayurvedic medicine for Gas and Indigestion
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...rightmanforbloodline
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest Versio
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest Version
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest VersionLocal Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Recently uploaded (20)
Role of Mukta Pishti in the Management of Hyperthyroidism
Role of Mukta Pishti in the Management of Hyperthyroidism
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Seminar on carcinoma penis
- 1. Seminar on carcinoma penis moderator • Dr A I Mazumder Asstt. Professor Deptt of surgery SMCH Presenter • Dr Biswajit Deka 2nd yr PGT Deptt of surgery SMCH
- 2. Anatomy
- 7. Introduction • Penile cancer is uncommon, but, when it is diagnosed, it is psychologically devastating to the patient • . Benign, premalignant, and malignant conditions must be differentiated. • Metastasis, which occurs when the diagnosis or treatment is delayed, is usually lethal. • This is a slow-growing cancer in its early stages, and because it seldom interferes with voiding or erectile function, patients do not complain until pain or a discharge from the cancer occurs. By this time, the cancer has usually progressed from being superficial to invasive.
- 8. Epidemiology • 0.5% of all malignancies in western world (decreasing) • Higher incidence- south America , east Africa & south east asia • In urban India- 0.7-2.3 cases per 100,000 men. • In rural India, 3 cases per 100,000 men, accounting for more than 6% of all malignancies in this population • Overall incidence is decreasing
- 9. Natural history • Begins as small lesion: papillary & exophytic or flat & ulcerative • Flat & ulcerative lesions >5cm & extending >75% of the shaft– higher incidence of metastasis & poor survival • Lymphatic spread • Metastatic nodes cause erosion into vessels , skin necrosis & chronic infection • Distant mets uncommon : 1-10% • Most untreated cases : death within 2 yrs
- 11. Presentation •Delayed presentation – embarrassment , anxiety , fear ( 5.8months ) •Lump 47% •Ulcer 35% •Erythematous lesion 17% •Bleeding & discharge from lesion •Usually sharply demarcated lesion
- 12. Location • Glans 48% • Prepuce 21% • Glans & prepuce 9% • Coronal sulcus 6 % • Shaft <2%
- 17. TNM classification : Primary tumour • Tx – primary tumour cannot be assessed • To- no evidence of primary tumour • Tis – ca in situ • Ta – non invasive verrucous ca • T1a – tumour invades subepithelial connective tissue without lymphovascular invasion & is not poorly differentiated • T1b - tumour invades subepithelial connective tissue without lymphovascular invasion & is poorly differentiated • T2- tumour invades corpus cavernosum or spongiosum • T3- tumour invades urethra • T4- tumour invades other adjacent structures
- 18. Lymph nodes • Nx - regional nodes cannot be assessed • No- no palpable or visibly enlarged inguinal LN • pNo- no regional LN metastasis • N1 – palpable, mobile , unilateral inguinal LN • pN1- metastasis in a single inguinal LN • N2-- palpable mobile multiple or B/L inguinal LN • pN2– metastasis in multiple or B/L inguinal LN • N3- palpable fixed inguinal nodal mass or pelvic LN U/L or B/L • pN3- extranodal extension of LN metastasis or pelvic LN U/L or B/L
- 19. Metastasis • Mo – no distant mets • M1 – distant mets
- 23. Broder’s grading • Very well differentiated (75% epithelial pearls) • Well differentiated (50-75%) • Moderately differentiated (25-50%) • Undifferentiated (<25%)
- 24. Grading of penile SSC Features Grade 1 Grade 2 Grade 3 Sarcomatoid ( grade 4 ) Cytological atypia Mild Moderate Anaplasia Sarcomatoid keratinisation Usually abundant Less prominent May be absent Absent Inter cellular bridges Prominent Occasional Few or more Absent Mitotic activity Rare Increased Abundant Abundant Tumour margin Pushing/ well defined Increased Infiltrative/ ill defined Abundant
- 25. Investigation • Routine inv • Edge biopsy • FNAC • USG abdomen – look for external iliac nodes • SLNB- CABANA node
- 46. Radiotherapy • Indication : early lesion , palliation , LN involvement • EBRT : widely available , delivers homogenous dose , less expertise • Brachytherapy : RADIUM-226 , IRIDIUM-192, CESIUM-137 • Dose: 60 cGy for 3 weeks (high dose) • Prophylactic – not recommended
- 50. Follow up • Most relapses in first 2 yrs • 0-7% chances of relapse after partial / total penectomy
- 55. Thank you