Screwworm infestation is caused by fly larvae that feed on living flesh of mammals and sometimes birds. The larvae are laid by screwworm flies near wounds and proceed to burrow and feed on tissue, creating large lesions. The flies prefer warm humid environments and have a life cycle that can be completed in under 20 weeks. Signs of infestation include wounds with visible maggots, licking, fever, and infected areas around common sites like heads, briskets, and navels. Diagnosis involves identifying the larvae in wounds. Treatment requires removing the larvae and cleaning the wound repeatedly with antiseptic solutions until it heals. Prevention strategies include wound cleaning and use of insecticide sprays and powders