Sclerosing agents are injected into unwanted veins to immediately shrink them and cause the veins to dissolve over weeks as the body absorbs them. Sclerosants include detergents, osmotic agents, and chemical irritants that disrupt or damage the vein's cellular membrane. Sclerosing agents are used to treat vascular malformations in children, as well as spider veins, smaller varicose veins, and hemorrhoids in adults.

1. SCLEROSING AGENT
By: Sahaya Asirvatham

2. Injecting the unwanted veins with a sclerosing
solution causes the target vein to immediately shrink,
and then dissolve over a period of weeks as the body
naturally absorbs the veins.

3. VARICOSE VEINS

5. SCLEROSING AGENT
Sclerosants include the following:
● Detergents ­ Disrupt vein cellular membrane (protein theft
denaturation)
Sodium tetradecyl sulfate (Sotradecol)
Ethanolamine Oleate (Ethamolin)
● Osmotic agents ­ Damage the cell by shifting the water balance through
cellular gradient (osmotic) dehydration and cell membrane denaturation
Hypertonic sodium chloride solution
Sodium chloride solution with dextrose (Sclerodex)
● Chemical irritants ­ Damage the cell wall by direct caustic destruction
of endothelium
Chromated glycerin (Sclermo)
Polyiodinated iodine

6. USES
● It is used for children and young adults
with vascular or lymphatic malformations.
● In adults, sclerotherapy is often used to
treat spider veins, smaller varicose veins,
and hemorrhoids.