Latinos in LA County have been disproportionately impacted by COVID-19, accounting for 64% of cases and over half of deaths despite being 49% of the population. They have higher risks like living in crowded households and working essential jobs. Vaccine enthusiasm is rising among Latinos but access barriers like transportation and trust must be addressed. While most Latinos adopted safety behaviors, risks remain from gatherings and challenges maintaining distancing in multi-generational households pose ongoing risks until widespread vaccination is achieved.