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Classification of Enzymes

 Enzymes are classified into six groups according to the type of reaction
 they catalyse:

                             Oxidoreductases
                              Transferases
                               Hydrolases
                                 Lyases
                               Isomerases
                                 Ligases


  Enzyme                   Type of Reaction
Class/Group                   Catalysed                      Examples
Oxidoreductases       Transfer of electrons or           Dehydrogenases,
                      Transfer of H and O atoms          oxidases,
                      between substances.                reductases
 Transferases         Transfer of specific/ function     Transaminases,
                      group from one molecule to         transmethylases.
                      another
  Hydrolases          Hydrolytic Cleavage                Phosphatases,
                      (Hydrolysis).                      Esterases,
                                                         peptidases,
                                                         glycosidases


 • Each enzyme is given two names
 • A systematic name based on one of the six groups above
 • A trivial name which is shorter and easier to use. It is derived as
   follows:
   • Start with the name of the substrate upon which the enzyme acts
       e.g. succinate
   • Add the name of the type of reaction which it catalyses e.g.
       dehydrogenation
   • Convert the end of the last word to an -ase suffix e.g
       dehydrogenase

 End result - Succinic dehydrogenase

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  • 1. Classification of Enzymes Enzymes are classified into six groups according to the type of reaction they catalyse: Oxidoreductases Transferases Hydrolases Lyases Isomerases Ligases Enzyme Type of Reaction Class/Group Catalysed Examples Oxidoreductases Transfer of electrons or Dehydrogenases, Transfer of H and O atoms oxidases, between substances. reductases Transferases Transfer of specific/ function Transaminases, group from one molecule to transmethylases. another Hydrolases Hydrolytic Cleavage Phosphatases, (Hydrolysis). Esterases, peptidases, glycosidases • Each enzyme is given two names • A systematic name based on one of the six groups above • A trivial name which is shorter and easier to use. It is derived as follows: • Start with the name of the substrate upon which the enzyme acts e.g. succinate • Add the name of the type of reaction which it catalyses e.g. dehydrogenation • Convert the end of the last word to an -ase suffix e.g dehydrogenase End result - Succinic dehydrogenase