The document provides revised guidelines for home isolation of very mild or pre-symptomatic COVID-19 cases in India. It outlines the eligibility criteria for home isolation, including having the facilities for self-isolation and a caregiver available full-time. It describes the instructions that must be followed by both the caregiver and patient regarding hygiene, use of protective equipment, monitoring for worsening symptoms, and criteria for ending isolation. Home isolation is permitted for 17 days after symptom onset if no fever is present for 10 days.