Common laboratory animals, Classification of Experimental Animals, Handling and application of different species and strains of animals,Different strains of laboratory animals, application and common diseases.
Anesthesia and euthanasia of experimental animal by vivek and naveenAnimatedWorld
Anesthesia and euthanasia of experimental animal by vivek and naveen
Anesthesia
It is a state of controlled temporary loss of sensation or awareness that or awareness that is induced for medical purpose.
Anesthetic agents
The anesthetic agents are great and choosing the correct one for particular suggestion.
In laboratory animal field , the anesthetic surgeon and post operative are often one and the same person.
This will help to chose correct drug for anaesthesia.
Sometime the wise anesthetic agents also cause undesirable responses. so, its responsibility of experimenters to document this advance in exprimental protocol
Euthanasia
The term euthanasia is derived from the Greek terms eu mean good and thanatos mean death.
Euthanasia is the act of including humane death in an animal. sacrificing the experimental animal after use by gentle procedure causing minimum of physical and mental suffering is called euthanasia.
Common laboratory animals, Classification of Experimental Animals, Handling and application of different species and strains of animals,Different strains of laboratory animals, application and common diseases.
Anesthesia and euthanasia of experimental animal by vivek and naveenAnimatedWorld
Anesthesia and euthanasia of experimental animal by vivek and naveen
Anesthesia
It is a state of controlled temporary loss of sensation or awareness that or awareness that is induced for medical purpose.
Anesthetic agents
The anesthetic agents are great and choosing the correct one for particular suggestion.
In laboratory animal field , the anesthetic surgeon and post operative are often one and the same person.
This will help to chose correct drug for anaesthesia.
Sometime the wise anesthetic agents also cause undesirable responses. so, its responsibility of experimenters to document this advance in exprimental protocol
Euthanasia
The term euthanasia is derived from the Greek terms eu mean good and thanatos mean death.
Euthanasia is the act of including humane death in an animal. sacrificing the experimental animal after use by gentle procedure causing minimum of physical and mental suffering is called euthanasia.
This slide is a result of colaboration of my group in our practicum during the semester break.....
its include a lot of simple basic things in physiology...
-animal handling
-blood grouping
-vaginal swab in female rats
-breathing n ECG
hope this will contribute something!
“A restraint is any manual method, physical or mechanical device, material or equipment that immobilizes or reduces the ability of a patient to move his/her arms, legs, body or head freely” (e.g. -Safe keeper bed, Posey bed, safety mitt, soft limb restraint), or a restraint is a drug or medication when it is used as a restriction to manage the patient's behavior or restrict the patient's freedom of movement and is not standard treatment or dosage for the patient's condition A restraint does not include devices, such as orthopedically prescribed devices, surgical dressings or bandages, protective helmets, or other methods that involve the physical holding of a patient for the purpose of conducting routine physical examinations or tests, or to protect the patient from falling out of bed, or to permit the patient to participate in activities without the risk of physical harm., side rails, airways, trapeze etc.
General anesthesia & obstetrics part IISandro Zorzi
→ Discuss indications of general anesthesia for operative delivery
→ Explain aspiration risk for general anesthesia in pregnancy and prevention strategy
Outline anaesthesia plan of care for induction, maintenance and emergency
Describe effect of volatile anaesthetics on uterine blood flow and tone
Discuss intraoperative strategies to prevent postoperative nausea and vomiting
Discuss other complications of general anaesthesia and clinical management
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
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- Link to NephroTube website: www.NephroTube.com
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Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
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In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
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Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Maxilla, Mandible & Hyoid Bone & Clinical Correlations by Dr. RIG.pptx
Restraining and blood withdrawal methods
1. Experimental Techniques in Pre-clinical Studies 10-3-2015 Pharmacology Dept PESCP Page 1
Restraining techniques, routes of drug administration and blood withdrawal techniques
Purpose: The purpose of this event of this workshop is to inform and instruct personnel on the
safe and the least stressful way for restraining, injecting and blood withdrawal techniques on
experimental animals.
Restraining techniques
Restraint: Restraint is defined as the immobilization of a conscious animal in a fixed position
for a significant period of time while an examination or procedure is going on.
Proper restraint is one of the main factors in administering drug or blood withdrawal techniques
limiting the amount of stress and/or discomfort to the animal or the handler.
When working with lab animals the two types of restraint that are utilized most often are
physical and chemical
Chemical restraint:
Chemical restraint is recommended if there will be great distress or discomfort to the animal.
This can be achieved by using a gas anesthesia such as isoflurane or by a type of injectable
sedation such as Ketamine/Xylazine mix.
Physical restraint:
Basic/Four finger hold: Head between index and third/ring finger, thumb and knuckles along
body to support chest. Support tail and body with other hand.
One Hand Restraint Technique:
With the non-dominant hand, grab the base of the tail with the thumb and index finger to keep
the rat from running away, leaving the dormant hand free for use.
With the same hand, place the palm of the hand on the rat’s back. With the thumb and fingers
gather the loose skin along the dorsum including that along the dorsal neck. The thumb and
index finger are utilized to stabilize the head while the other three fingers stabilize the trunk.
2. Experimental Techniques in Pre-clinical Studies 10-3-2015 Pharmacology Dept PESCP Page 2
Be careful not to grasp too tight as this may compromised breathing.
Two Hand Restraint Techniques
With the non-dominant hand, grab the base of the tail with the thumb and index finger to keep
the rat from running away.
Next, with the other hand quickly and firmly grasp the rat/mice by the scruff of the neck.
With the tail in one hand and the scruff in the other, lift the animal between the palm and
the fingers.
Route of administration
Numerous routes have been documented in literature, as every route has both advantages as well
as disadvantages for instance, the absorption, bioavailability and metabolism of the substance.
The disposition and fate of the administered substance helps the scientists to choose the most
suitable route for administration.
a. Intra muscular route (IM)
Insert the needle into the large muscle mass posterior the femur. Requirements-Disposable
gloves, 1ml syringe, hypodermic needle- 22-30G. Max- 0.3 ml can be administered.
b. Subcutaneous injection (SC)
SQ injections are usually given in the scruff (access skin) of the neck or using the scruff back in
the hind quarters by tenting the skin. Requirements- syringe, hypodermic needle- 22-30G. Max -
5ml can be administered.
c. Intradermal injection (ID)
Given into the thick dermal skin layer. Needle directed at 20 to 30 degree angle into skin.
Requirements- 1ml syringe, hypodermic needle- 25-30G. Only small quantity of fluid 0.1 to 0.2
ml can be injected.
d.Intraperitoneal injection(IP)
3. Experimental Techniques in Pre-clinical Studies 10-3-2015 Pharmacology Dept PESCP Page 3
Insert needle into lower left/right quadrant of abdomen at a 30-degree angle to avoid hitting such
organs as liver, bladder, and cecum. Requirements- 1-3 ml syringe, hypodermic needle- 22-30G.
Max- 5ml can be administered.
e. Intravenous injection (IV)
Injection site- lateral vein, Insert the needle at 30 degree angle to skin. Requirements-
Restrainer, syringe, hypodermic needle- 25-30G. Max- 0.5ml. Dipping the tail in warm water
(45ºC) will dilate the vessels and facilitate injections.
f. Oral gavage route
Measure the distance from the tip of nose to the first rib. This is the length of needle that should
be used. Restrain the shoulders of the rat by your thumb and index finger, then support the lower
limbs with your right hand. Restrain the tail of the rat in between your ring finger and little
finger. Let the rat lying on your left palm and introduce the ball-tipped feeding needle from the
pharynx in to the esophagus when the rat is in the act of swallowing.
4. Experimental Techniques in Pre-clinical Studies 10-3-2015 Pharmacology Dept PESCP Page 4
Blood withdrawal techniques in rats
Blood volume- 6% of the body weight. For eg 200g rat-12ml. Weekly 1% of the body weight
blood can be collected. For eg 200g rat- 2ml blood can be withdrawn.
a. Blood collection by retro orbital sinus
This method may be used to collect large volumes of blood. This should be performed under
anesthesia. Requirement- Cotton, capillary tube and capillary tubes, eppendorff tubes.
b. Blood collection from saphenous vein
The saphenous Vein is located along the lower portion of the hind leg. This technique is used for
collecting small volumes of blood. Multiple samples collected in same day. Needle- 23G
c. Blood collection by lateral tail vein
Used to collect a small to medium volume of blood. Using a sterile scalpel blade, nick the lateral
tail vein as shown in this picture. After collection of blood, apply gentle pressure to stop
bleeding.